Research News and Research

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Deeper grief correlates with an overarching decline in quality of life, shows study

How will you cope with the death of your mother or spouse? Their death may disturb your concentration, causing accidents or lowering your productivity. Some bereaved cannot sleep, and others cannot get out of bed.

6 Oct 2020

Research indicates increased breast cancer mortality in African American and Black survivors

Although breast cancer does not discriminate between race or gender, research suggests that there is increased breast cancer mortality and poorer health-related quality of life in female African American and Black survivors of the disease.

6 Oct 2020

New algorithm can fast forward quantum simulations to solve problems

A new algorithm that fast forwards simulations could bring greater use ability to current and near-term quantum computers, opening the way for applications to run past strict time limits that hamper many quantum calculations.

6 Oct 2020

Study provides new solution to offset the cost of medical scribes

Requirements for electronic health records are greater now than ever, and that burden is exacerbating the problem of physician burnout. However, there might be a solution: the medical scribe.

6 Oct 2020

HPV vaccination mandates did not improve rates of HPV vaccine series completion, shows study

A postdoctoral researcher at the University of California, Riverside, has discovered human papillomavirus, or HPV, vaccination mandates fall short of ensuring both higher levels of uptake and equal uptake of the vaccine across socioeconomic and racial-ethnic groups.

6 Oct 2020

IL-21 protein is a major part of immune response to chronic infections in the central nervous system

Researchers at Penn State College of Medicine now better understand the role of a protein, interleukin-21 (IL-21), in the immune system response to infections in the nervous system.

6 Oct 2020

CODA trial shows antibiotics may be a good choice for certain patients with appendicitis

Antibiotics may be a good choice for some, but not all, patients with appendicitis, according to results from the Comparing Outcomes of antibiotic Drugs and Appendectomy (CODA) Trial reported today in the New England Journal of Medicine.

6 Oct 2020

Higher vitamin D levels in pregnancy may protect children from developing high blood pressure

Children appear to be at greater risk of having high blood pressure when their mothers had the high blood pressure condition called preeclampsia during pregnancy--but this adverse association may be reduced or even eliminated for children who were exposed to higher levels of vitamin D in the womb, according to a study from researchers at Johns Hopkins Bloomberg School of Public Health.

6 Oct 2020

Programs known to reverse the negative effects of poverty are being widely neglected, shows report

The coronavirus (COVID-19) pandemic has caused widespread harm to the health and well-being of already vulnerable children and adolescents in the U.S., particularly those in low-income households and children of color.

6 Oct 2020

Antibiotic treatment is as good as appendectomy for a majority of adults with appendicitis

Seven of 10 adults with appendicitis can safely avoid surgical removal of their appendix (appendectomy) for at least several months by receiving a course of antibiotics, according to early results of a U.S. study that is the largest to compare use of these drugs alone versus an operation for appendicitis treatment.

6 Oct 2020

Study shows why antiretroviral therapy does not work in certain HIV patients

Increasingly, UPMC's chief of infectious diseases - a well-regarded expert in HIV/AIDS - is contacted by a perplexed physician describing a patient with HIV who insists they are adhering to the daily medication regimen meant to keep the virus in check, but testing says otherwise.

6 Oct 2020

Chronic illnesses promote active SARS-CoV-2 infection via suppressed mucosal immunity

A recent paper published in the preprint server medRxiv in September 2020 discusses the “clinically relevant variation in the expression of COVID-19-related genes”, which is associated with the host and environmental factors, as well as host genetic factors.

6 Oct 2020

Production of six monoclonal antibodies against SARS-CoV-2 spike protein

Youjia Guo et al. in a recent bioRxiv preprint paper demonstrate the robust performance of mouse anti-SARS-CoV-2 spike monoclonal antibodies in immunoassays, including western blotting, ELISA, immunofluorescence, and immunoprecipitation and also neutralizing activity in vitro against SARS-CoV-2 infection.

5 Oct 2020

Eli Lilly's LY-CoV555 antibody shows potential as COVID-19 treatment

Researchers in the United States and Canada have discovered a monoclonal antibody that potently neutralizes severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent responsible for the current coronavirus disease 2019 (COVID-19) pandemic.

5 Oct 2020

New findings could improve investigation of T cell response to COVID-19

Researchers in the United States have made an important discovery about the processing and presentation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral peptides that provides a better understanding of the immune response to coronavirus disease 2019 (COVID-19) and may help facilitate the design of improved vaccines.

5 Oct 2020

Study confirms SARS-CoV-2 spike glycoprotein promotes a hyper-inflammatory immune response

A group of researchers from Australia and China recently demonstrated how SARS-CoV-2 spike glycoprotein subunit 1 can induce a pro-inflammatory signaling pathway (leading to cytokines deployment and epithelial damage in human bronchial epithelial cells), but also highlighted the potential of peptide-based antivirals in tackling this novel coronavirus.

5 Oct 2020

Severe COVID-19 in pregnancy increases risk for adverse maternal and neonatal outcomes

A new study published in the American Journal of Obstetrics and Gynecology in September 2020 reports the impact of severe COVID-19 on pregnancy, making an important contribution to the management of the condition in this subgroup of patients.

5 Oct 2020

Macrophage subgroups may play pivotal role in COVID-19 lethality

Many researchers are attempting to identify risk factors for severe or critical COVID-19. A recent paper in the journal Medical Hypotheses in September 2020 suggests that macrophage class activation is one of the factors that determine the clinical phenotype of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

5 Oct 2020

Mental health of undocumented college students worst hit by COVID-19 pandemic

A new study by researchers at Delaware State University and published on the preprint server medRxiv in September 2020 reports that the impact on mental health is disproportionately felt among undocumented immigrants studying in US colleges.

5 Oct 2020

Individual and socioeconomic factors associated with COVID infection, hospitalization and death

The coronavirus disease (COVID-19) pandemic is actively spreading across nations, with millions of people affected. In the United States alone, more than 7.45 million people have been infected, and more than 210,000 have died.

5 Oct 2020

Research News and Research

Deeper grief correlates with an overarching decline in quality of life, shows study

Research indicates increased breast cancer mortality in African American and Black survivors

New algorithm can fast forward quantum simulations to solve problems

Study provides new solution to offset the cost of medical scribes

HPV vaccination mandates did not improve rates of HPV vaccine series completion, shows study

IL-21 protein is a major part of immune response to chronic infections in the central nervous system

CODA trial shows antibiotics may be a good choice for certain patients with appendicitis

Higher vitamin D levels in pregnancy may protect children from developing high blood pressure

Programs known to reverse the negative effects of poverty are being widely neglected, shows report

Antibiotic treatment is as good as appendectomy for a majority of adults with appendicitis

Study shows why antiretroviral therapy does not work in certain HIV patients

Chronic illnesses promote active SARS-CoV-2 infection via suppressed mucosal immunity

Production of six monoclonal antibodies against SARS-CoV-2 spike protein

Eli Lilly's LY-CoV555 antibody shows potential as COVID-19 treatment

New findings could improve investigation of T cell response to COVID-19

Study confirms SARS-CoV-2 spike glycoprotein promotes a hyper-inflammatory immune response

Severe COVID-19 in pregnancy increases risk for adverse maternal and neonatal outcomes

Macrophage subgroups may play pivotal role in COVID-19 lethality

Mental health of undocumented college students worst hit by COVID-19 pandemic

Individual and socioeconomic factors associated with COVID infection, hospitalization and death

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