Genome News and Research

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Developing new approaches to fight against multi-resistant pathogens

Developing fundamentally new approaches against multi-resistant germs: This is the goal of the new Bavarian research network bayresq.net which started in January 2020.

9 Feb 2020

Understanding the genetic background of idiopathic ketotic hypoglycemia

Lisa is two years old. She often gets uneasy--shaking and sweating--especially in the morning. She vomits and refuses to eat. Her mother, Karoline, knows she has to act before Lisa starts to deteriorate.

9 Feb 2020

Genomic sequencing technique helps understand gut microbiota one cell at a time

A population of microorganisms living in our intestine, known as the gut microbiota, plays a crucial role in controlling our metabolism and reducing the risk of conditions such as obesity and diabetes.

9 Feb 2020

Researchers offer new hope for diagnosis, treatment of age-related macular degeneration

Researchers have identified a new protein linked to age-related macular degeneration (AMD) that could offer new hope for the diagnosis and treatment of the disease, which affects over 1.5 million people in the UK alone.

8 Feb 2020

New gene therapy improves vision in blind mice

Mice born blind have shown significant improvement in vision after undergoing a new gene therapy developed by a team of Japanese scientists.

7 Feb 2020

CDC diagnostic coronavirus test gets FDA emergency approval

In the light of the ongoing novel coronavirus epidemic in China, the US Food and Drug Administration has granted approval of a diagnostic test for use in emergency situations (emergency use authorization or EUA). The viral infection has spread to many different and distant parts of the world, involving over 25,000 people and causing nearly 600 deaths since it started in December 2019.

6 Feb 2020

Largest genome study sheds light on how genetic glitches trigger tumor formation

It is well-known that when a gene mutates, it triggers tumor formation by stimulating abnormal cell growth and proliferation. Cancer starts from a mutant gene that kickstarts a series of abnormal growth, forming a tumor. However, the exact mechanism of how this happens remains unclear.

6 Feb 2020

Genetic fingerprints could help identify cancer-causing culprits

Causes of cancer are being cataloged through an international study revealing the genetic fingerprints of DNA-damaging processes that drive cancer development.

6 Feb 2020

Researchers compile large catalog of cancer mutations

Mutations in 38 different types of cancer have been mapped by means of whole genome analysis by an international team of researchers from, amongst others, the University of Copenhagen, Aarhus University, Aarhus University Hospital, and Rigshospitalet.

6 Feb 2020

Study lays foundation for translating mitochondrial biology into clinical applications

A study led by The University of Texas MD Anderson Cancer Center furthered understanding about mitochondria, the cell components known as the "powerhouse of the cell." Knowing more about the genome is crucial given that mitochondria play important roles in tumorigenesis.

6 Feb 2020

Researchers discover new mutational phenomenon chromothripsis in cancer

Researchers at Harvard Medical School and EMBL-EBI have carried out the largest analysis across cancer types of the newly discovered mutational phenomenon chromothripsis.

6 Feb 2020

New insight into genomic alterations associated with telomere maintenance mechanisms in cancer

To gain an infinite lifespan, cancer cells need to maintain the ends of their chromosomes, known as telomeres. They achieve this in various different ways.

6 Feb 2020

Analyzing cancer-specific alterations found in tumor's RNA

Researchers at EMBL-EBI were among the leaders of a large international consortium that carried out a joint analysis of data from over 1000 donors of more than 25 cancer types, studying data on their whole genomes along with tumor transcriptome data, which indicates the genes that are active within a tumor.

6 Feb 2020

Researchers study how structural variations in the genome can lead to cancer

Structural variations in genomes can arise from deleting, amplifying, or reordering genomic segments ranging from a few thousand letters of the genetic code to whole chromosomes.

6 Feb 2020

First comprehensive survey of viruses found within different cancers

Researchers from the University of East Anglia have helped to carry out the first comprehensive survey of viruses found within different types of cancer.

5 Feb 2020

Cancer mutations may arise decades before diagnosis

Researchers at EMBL's European Bioinformatics Institute and the Francis Crick Institute have analyzed the whole genomes of over 2600 tumors from 38 different cancer types to determine the chronology of genomic changes during cancer development.

5 Feb 2020

Researchers discover new genetic drivers of cancer

The discovery of genetic drivers of cancer can have critical implications for the diagnosis and treatment of cancer patients, yet genome analysis has focused primarily on only 1-2% of the whole genome - the part that contains the code for making proteins.

5 Feb 2020