Inflammation News and Research

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The impact of PLEX on the survival of patients with severe COVID-19 and the effect on the cytokine release syndrome

Researchers evaluated the survival benefit conferred by PLEX in patients with severe COVID-19 and cytokine-storm syndrome.

14 Mar 2022

Exercise counters inflammation that leads to diabetes, depression after COVID-19

While no medically recognized treatment exists for Long COVID, exercise may break the vicious cycle of inflammation that can lead to developing diabetes and depression months after a person recovers from the virus.

11 Mar 2022

Mild SARS-CoV-2 infection leads to tissue damage and shrinkage in brain areas related to smell

Researchers from the University of Oxford have used data from UK Biobank participants to look at changes to the brain on average 4.5 months after mild SARS-CoV-2 infection.

11 Mar 2022

Mice study shows how to improve long-term effectiveness of TB vaccine

Briefly blocking a key molecule when administering the only approved vaccine for tuberculosis vastly improves long-term protection against the devastating disease in mice, researchers from Texas Biomedical Research Institute report this week in the Journal of Immunology.

11 Mar 2022

Novel genetic relationships with severe SARS-CoV-2

Researchers discovered multiple novel genetic processes underpinning severe COVID-19 using genome-wide association studies and meta-analyses.

11 Mar 2022

Researchers solve the structure of large signaling protein involved in emergence of blood cancers

Researchers led by Christopher Garcia of the Ludwig Center at Stanford University have solved the long-sought structure of a large signaling protein involved in responses to infection, inflammation, the generation of immune cells and when dysregulated by mutation - the emergence of blood cancers known as myeloproliferative neoplasms.

11 Mar 2022

Blood test shows promise to identify Alzheimer's changes in the brain before symptom onset

The University of Kentucky's Sanders-Brown Center on Aging has been around for nearly half a century. In that time, they have built an international reputation for best-in-class research into a disease that kills more people every year than breast and prostate cancer combined – Alzheimer's disease.

10 Mar 2022

Cellular therapy offers promise for patients with Duchenne muscular dystrophy, trial shows

A clinical trial at UC Davis Health and six other sites showed that a cellular therapy offers promise for patients with late-stage Duchenne muscular dystrophy (DMD), a rare genetic disorder causing muscle loss and physical impairments in young people.

10 Mar 2022

Long-lasting immune activity in the airways may be the cause of persistent post-COVID-19 breathlessness

Long-lasting immune activity in the airways might be the cause of persistent breathlessness following COVID-19.

10 Mar 2022

Causal links between severe COVID-19 and blood proteins identified via proteome-wide Mendelian randomization in new study

A recent study was based on Mendelian randomization analyses conducted between high levels of numerous blood proteins and COVID-19.

9 Mar 2022

Pain neuron-derived peptide protects mice from endotoxic death by enhancing brain ATP production

Sepsis is a high-mortality disease that arises when the body's immune reaction to pathogens causes multi-organ defects.

9 Mar 2022

Low SARS-CoV-2 diabetogenicity found in infected human pancreatic cells in vitro

Researchers assessed the diabetogenic potential of SARS-CoV-2 in a single cell in vitro analysis on the pancreatic islet cells.

9 Mar 2022

Mathematical model for evaluating factors driving SARS-CoV-2 transmission and pathogenesis

A new study provides an overview of the use of mathematical modeling to determine severe acute respiratory syndrome coronavirus 2 kinetics.

9 Mar 2022

Elevated P2X7 receptor levels in COVID-19 patients correlate with disease severity

In a recent study posted to the bioRxiv preprint server, researchers demonstrated that the soluble P2X7 receptor is increased in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients. They also showed that the elevated P2X7 receptors correlated with coronavirus disease 2019 (COVID-19) severity.

9 Mar 2022

Biomedical characterization of quantitative proteomics in a hospitalized cohort of COVID-19 patients

A recent study assessed neutrophil extracellular trap formation and antiviral host response in high-risk COVID-19 patients.

8 Mar 2022

Relationship between immunological responses in the acute phase of SARS-CoV-2 infection and long-term cognitive deficits

A recent study reported that monocytosis during the acute phase of coronavirus disease 2019 could forecast anosognosia in long COVID.

8 Mar 2022

Older adults under severe financial strain more likely to die within six months after heart attack

Older adults who report being under severe financial strain were substantially more likely to die within six months of having a heart attack compared to those with moderate or no financial strain, according to a new study led by University of Maryland School of Medicine researchers.

7 Mar 2022

Inflammation News and Research

The impact of PLEX on the survival of patients with severe COVID-19 and the effect on the cytokine release syndrome

Exercise counters inflammation that leads to diabetes, depression after COVID-19

Mild SARS-CoV-2 infection leads to tissue damage and shrinkage in brain areas related to smell

Mice study shows how to improve long-term effectiveness of TB vaccine

Novel genetic relationships with severe SARS-CoV-2

Researchers solve the structure of large signaling protein involved in emergence of blood cancers

Blood test shows promise to identify Alzheimer's changes in the brain before symptom onset

Cellular therapy offers promise for patients with Duchenne muscular dystrophy, trial shows

Long-lasting immune activity in the airways may be the cause of persistent post-COVID-19 breathlessness

Causal links between severe COVID-19 and blood proteins identified via proteome-wide Mendelian randomization in new study

Pain neuron-derived peptide protects mice from endotoxic death by enhancing brain ATP production

Low SARS-CoV-2 diabetogenicity found in infected human pancreatic cells in vitro

Mathematical model for evaluating factors driving SARS-CoV-2 transmission and pathogenesis

Elevated P2X7 receptor levels in COVID-19 patients correlate with disease severity

Biomedical characterization of quantitative proteomics in a hospitalized cohort of COVID-19 patients

Relationship between immunological responses in the acute phase of SARS-CoV-2 infection and long-term cognitive deficits

Older adults under severe financial strain more likely to die within six months after heart attack

Biodegradable nanoparticle used in medical sutures could help combat scleroderma

World's largest genetic study reveals fresh details about severe Covid-19

Some blood cells remain in tissues for years, research finds

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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