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Researchers lab-test molecule that may combat common cold virus

Researchers have lab-tested a molecule that can combat the common cold virus by preventing it from hijacking human cells.

15 May 2018

Researchers discover unique mechanism that regulates tumor growth in lung cancer

Lung cancer is the third most common type of cancer in Germany and the disease affects both men and women. However, immunotherapies are successful in only 20 percent of cases.

14 May 2018

Heart failure severity could vary based on the body's nitric oxide levels

The most common heart medications may get an assist from nitric oxide circulating in the body, according to a new study out of Case Western Reserve University School of Medicine.

14 May 2018

Phase 1/2 study evaluates safety, tolerability of multiple-ascending doses of ARO-HBV in hepatitis B patients

Arrowhead Pharmaceuticals Inc. today announced that it has dosed the first 3 hepatitis B virus patients in the multiple-ascending dose portion of its ongoing Phase 1/2 study of ARO-HBV, the company's third generation subcutaneously administered RNA interference therapeutic being developed as a potentially curative therapy for patients with chronic HBV infection.

14 May 2018

Researchers screen molecules that could be potential target for prostate cancer treatments

Cancer researchers at the University of Bath have measured systematically how efficient molecules are at suppressing the activity of a protein associated with prostate and other cancers. The molecules could eventually be developed into new anti-cancer drugs.

14 May 2018

Taurine deficiency in sperm linked to male infertility

Sperm are highly specialized cells adapted to achieve a single goal: fertilize an egg. Along the road to fertilization sperm must embark on a lengthy journey to the female oviduct, avoiding several fatal stresses that occur when they pass through different physiological environments.

11 May 2018

New study aims to mitigate risks associated with treatment of multiple myeloma

In a 10-patient cohort study led by Dr. Jean Roy that aims to understand how to mitigate the risks associated with the treatment of multiple myeloma, a malignant cancer, researchers have adopted an innovative approach based on the unique immunological properties of umbilical cord blood in an effort to improve the safety and efficiency of allografting, the preferred treatment for this disease

11 May 2018

Scientists discover a mechanism through which HIV determines the fate and function of cells

A stem cell is one with infinite possibilities. So, for decades, scientists have puzzled over how the cell chooses to keep being a stem cell and continue dividing, or specialize into a specific cell type, like a heart or brain cell.

11 May 2018

Aravive Biologics demonstrates proof-of-mechanism for AVB-S6-500 in ongoing phase 1 study

Aravive Biologics, Inc. announced today that the company has demonstrated clinical proof-of-mechanism for AVB-S6-500 in neutralizing GAS6, based on analysis of the single ascending dose portion of the ongoing Phase 1 study.

10 May 2018

Phase 2 study of dexpramipexole in hypereosinophilic syndromes meets its co-primary endpoints

Knopp Biosciences LLC today announced the publication of a report in the journal Blood that a Phase 2 study of dexpramipexole in hypereosinophilic syndromes met its co-primary endpoints.

10 May 2018

New model based on combination of GANs with reinforcement learning for drug discovery

Insilico Medicine, a Baltimore-based next-generation artificial intelligence company specializing in the application of deep learning for target identification, drug discovery and aging research announces the publication of a new research paper in Molecular Pharmaceutics journal titled "Adversarial Threshold Neural Computer for Molecular De Novo Design".

10 May 2018

New research may help elucidate racial differences in prostate cancer

New research published in Molecular Oncology may help explain why African American men are at a higher risk of being diagnosed with prostate cancer and a higher risk of dying from the disease compared with European American men.

9 May 2018

Johns Hopkins researchers identify protein clumps in diseased hearts

Similar to how protein clumps build up in the brain in people with some neurodegenerative diseases such as Alzheimer's and Parkinson's diseases, protein clumps appear to accumulate in the diseased hearts of mice and people with heart failure, according to a team led by Johns Hopkins University researchers.

9 May 2018

ONC201 disrupts mitochondrial function and kills breast cancer cells, reveals study

TRAIL, a member of the TNF family of ligands, causes caspase-dependent apoptosis through activation of its receptors, death receptor 4 and DR5.

9 May 2018

New MRI glove prototype shows promise in future diagnosis of repetitive strain injuries

A new kind of MRI component in the shape of a glove delivers the first clear images of bones, tendons and ligaments moving together, a new study finds.

9 May 2018

New findings point to potential therapeutic avenues for leukemia

Scientists have known for decades that the Hox family of transcription factors are key regulators in the formation of blood cells and the development of leukemia.

9 May 2018

Empa researchers reveal how steam causes severe burns

Whether working with steam pipes or in the kitchen: When boiling hot steam hits the skin, it will quickly cause burns. Firefighters are also at risk - due to their own sweat: If it evaporates under the heavy protective clothing in the heat of the fire and cannot escape, it condenses on the cooler skin and burns it.

9 May 2018

Scientists discover how potential new drug targets spinal muscular atrophy

Spinal muscular atrophy (SMA) is a genetic disease that can leave infants with weak muscles and trouble breathing. Many with the disease die before age two. To help these patients, doctors need therapies that target the genetic mutation and stop its progression.

8 May 2018

Researchers create a biomaterial that can be used to study the brain

Researchers have created a new type of biomaterial that can support the growth of nerve cells, potentially opening up new possibilities for patients who have experienced a stroke or traumatic brain injury.

8 May 2018

New chemical trap catches trace glycoproteins, shows promise for targeted cancer treatments

Cancer drops sparse chemical hints of its presence early on, but unfortunately, many of them are in a class of biochemicals that could not be detected thoroughly, until now.

8 May 2018

Molecule News and Research

Researchers lab-test molecule that may combat common cold virus

Researchers discover unique mechanism that regulates tumor growth in lung cancer

Heart failure severity could vary based on the body's nitric oxide levels

Phase 1/2 study evaluates safety, tolerability of multiple-ascending doses of ARO-HBV in hepatitis B patients

Researchers screen molecules that could be potential target for prostate cancer treatments

Taurine deficiency in sperm linked to male infertility

New study aims to mitigate risks associated with treatment of multiple myeloma

Scientists discover a mechanism through which HIV determines the fate and function of cells

Aravive Biologics demonstrates proof-of-mechanism for AVB-S6-500 in ongoing phase 1 study

Phase 2 study of dexpramipexole in hypereosinophilic syndromes meets its co-primary endpoints

New model based on combination of GANs with reinforcement learning for drug discovery

New research may help elucidate racial differences in prostate cancer

Johns Hopkins researchers identify protein clumps in diseased hearts

ONC201 disrupts mitochondrial function and kills breast cancer cells, reveals study

New MRI glove prototype shows promise in future diagnosis of repetitive strain injuries

New findings point to potential therapeutic avenues for leukemia

Empa researchers reveal how steam causes severe burns

Scientists discover how potential new drug targets spinal muscular atrophy

Researchers create a biomaterial that can be used to study the brain

New chemical trap catches trace glycoproteins, shows promise for targeted cancer treatments

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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