Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

Novel nanomedicine prolongs survival of pancreatic tumor-bearing mice

A new Tel Aviv University study pinpoints the inverse correlation between a known oncogene -- a gene that promotes the development of cancer -- and the expression of an oncosuppressor microRNA as the reason for extended pancreatic cancer survival.

2 Jan 2018

Macrophages play major role in helping early breast cancer cells spread even before tumor develops

Mount Sinai researchers have discovered that normal immune cells called macrophages, which reside in healthy breast tissue surrounding milk ducts, play a major role in helping early breast cancer cells leave the breast for other parts of the body, potentially creating metastasis before a tumor has even developed, according to a study published in Nature Communications.

2 Jan 2018

Experts report new guidelines for clinical trial design in patients with brain metastases

Clinical trials of new anti-cancer therapies have often excluded patients whose disease has spread to the brain or central nervous system (CNS) or, if such patients were allowed on trial, trials have often failed to clearly capture information on the drug's effect in the brain.

30 Dec 2017

Blueberry extract can enhance effectiveness of cervical cancer treatment

According to the Centers for Disease Control and Prevention, approximately 12,000 women in the United States are diagnosed with cervical cancer each year.

29 Dec 2017

Proteasome inhibitor treatment can lead to cardiovascular problems in multiple myeloma patients

The proteasome inhibitor carfilzomib has taken on an increasing role in the treatment of multiple myeloma, but new research from the Abramson Cancer Center of the University of Pennsylvania shows the therapy comes with the risk of cardiovascular problems in a higher than expected percentage of patients.

28 Dec 2017

IQWiG experts contradict MINDACT study data on biomarker tests for breast cancer

The American Society of Clinical Oncology recently updated its guideline on biomarkers with regard to the MammaPrint test and published this update in the Journal of Clinical Oncology.

27 Dec 2017

Novel GammaPod system receives FDA clearance to treat early stage breast cancer

The GammaPod - a first-of-its kind stereotactic radiotherapy system to treat early stage breast cancer - has received 510(k) clearance from the U.S. Food and Drug Administration, paving the way for the manufacturer to bring the system to market for the treatment of breast cancer patients.

26 Dec 2017

Nanobiotix receives FDA approval for first immuno-oncology trial

NANOBIOTIX, a late clinical-stage nanomedicine company pioneering new approaches to the treatment of cancer, today announced the U.S. Food and Drug Administration has approved its Investigational New Drug Application for NBTXR3, a first-in-class nanoparticle designed for direct injection into cancerous tumors, activated by stereotactic ablative radiotherapy (SABR) and administered in combination with an anti-PD1 antibody (nivolumab or pembrolizumab).

26 Dec 2017

Novartis announces FDA approval of its first and only CML therapy with TFR data in product label

Novartis announced today that the US Food and Drug Administration (FDA) approved the inclusion of Treatment-free Remission (TFR) data in the Tasigna® (nilotinib) US product label.

26 Dec 2017

Novel radiotherapy system receives FDA clearance for treating early stage breast cancer

The GammaPod – a first-of-its kind stereotactic radiotherapy system to treat early stage breast cancer – has received 510(k) clearance from the U.S. Food and Drug Administration, paving the way for the manufacturer to bring the system to market for the treatment of breast cancer patients.

22 Dec 2017

Proton therapy center for treating cancer patients coming to Utah

A new cancer treatment technology is one step closer to Salt Lake City. Today Huntsman Cancer Institute at the University of Utah announced a plan to add a proton therapy center to its Cancer Hospital.

22 Dec 2017

UW study finds how tightly bound protein complexes are broken apart to become inactivated

A new study by University of Wisconsin-Madison researchers identified the structural basis for how tightly bound protein complexes are broken apart to become inactivated.

22 Dec 2017

Higher ‘mutational burden’ of tumors predicts success rate with cancer immunotherapies

The "mutational burden," or the number of mutations present in a tumor's DNA, is a good predictor of whether that cancer type will respond to a class of cancer immunotherapy drugs known as checkpoint inhibitors, a new study led by Johns Hopkins Kimmel Cancer Center researchers shows.

21 Dec 2017

Loss of specific protein makes breast cancers more aggressive, resistant to chemotherapy

Researchers in Italy have discovered how specific versions of a protein called Numb protect the key tumor suppressor p53 from destruction.

21 Dec 2017

Novel drug shows promise in treating metastatic kidney cancer

Metastatic kidney cancer remains largely incurable. Despite a dozen treatments and several immunotherapies, survival rates beyond 5 years remain around 10 percent.

21 Dec 2017

Study findings could lead to less expensive and more effective cancer treatments

The latest generation of cancer treatments spring from the discovery that the human immune system is able to beat the disease. Like Dorothy in "The Wizard of Oz," what research teams around the world have spent decades searching for was right in their own backyard all along.

20 Dec 2017

High out-of-pocket costs act as barrier to potentially life-saving cancer treatments

Sticker shock may be leading many insured Americans with cancer to forego treatment with a wide range of oral cancer drugs, suggests a study published online this week in the Journal of Clinical Oncology.

20 Dec 2017

Certain brain tumor patients more likely to receive short hospice services, study finds

While more than 60 percent of patients with the brain tumors called malignant gliomas enroll in hospice services, almost a quarter of them do so within a week of death, probably too late for patients and family members to benefit from hospice care.

20 Dec 2017

Smartphone app can detect worsening symptoms during cancer treatments

Cancer patients receiving chemotherapy can be remotely monitored using their smartphone sensors and an algorithm that detects worsening symptoms based on objective changes in patient behavior, according to a new study from the University of Pittsburgh and UPMC Hillman Cancer Center.

20 Dec 2017

Portable technique produces rapid blink measurements for assessing neurological function

The blink reflex has been shown to be sensitive to a number of neurological insults, including traumatic brain injury, Parkinson's disease and Huntington's disease, suggesting that it could be a useful tool for neurological assessment.

20 Dec 2017

Oncology News and Research

Further Reading

Novel nanomedicine prolongs survival of pancreatic tumor-bearing mice

Macrophages play major role in helping early breast cancer cells spread even before tumor develops

Experts report new guidelines for clinical trial design in patients with brain metastases

Blueberry extract can enhance effectiveness of cervical cancer treatment

Proteasome inhibitor treatment can lead to cardiovascular problems in multiple myeloma patients

IQWiG experts contradict MINDACT study data on biomarker tests for breast cancer

Novel GammaPod system receives FDA clearance to treat early stage breast cancer

Nanobiotix receives FDA approval for first immuno-oncology trial

Novartis announces FDA approval of its first and only CML therapy with TFR data in product label

Novel radiotherapy system receives FDA clearance for treating early stage breast cancer

Proton therapy center for treating cancer patients coming to Utah

UW study finds how tightly bound protein complexes are broken apart to become inactivated

Higher ‘mutational burden’ of tumors predicts success rate with cancer immunotherapies

Loss of specific protein makes breast cancers more aggressive, resistant to chemotherapy

Novel drug shows promise in treating metastatic kidney cancer

Study findings could lead to less expensive and more effective cancer treatments

High out-of-pocket costs act as barrier to potentially life-saving cancer treatments

Certain brain tumor patients more likely to receive short hospice services, study finds

Smartphone app can detect worsening symptoms during cancer treatments

Portable technique produces rapid blink measurements for assessing neurological function

Your guide to microplate readers for cancer research eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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