Clinical Trial News and Research

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Young male cancer survivors may benefit from testosterone replacement therapy

Young male cancer survivors may significantly benefit from testosterone replacement therapy - especially after testicular cancer - according to the first ever clinical trial of its kind.

12 Nov 2019

New study sounds a note of caution in using probiotics in ICU

It's become common for patients in the intensive care unit (ICU), both children and adults, to receive probiotics. Often, they are started at home to counteract diarrhea caused by antibiotics. There is also interest in using probiotics proactively in the ICU. A large multicenter clinical trial in Canada is testing whether probiotics would prevent ventilator-associated pneumonia in adult ICU patients.

12 Nov 2019

Scientists identify new mechanism for the development of Parkinson's disease

An international research team including scientists from the University of Cologne have identified a new mechanism for the development of Parkinson's disease, which could prove to be the starting point for the development of a more targeted therapy.

12 Nov 2019

Researchers uncover new and unexploited drug target for childhood cancer

An Australian-led international research effort has broken fresh ground in the race to find more effective treatments for the childhood cancer neuroblastoma, by uncovering a new and as-yet unexploited target in cancer cells that therapeutic drugs can be aimed at.

12 Nov 2019

Rutgers researcher receives $600,000 grant to study chronic lymphocytic leukemia

Rutgers Cancer Institute of New Jersey researcher Hossein Khiabanian, PhD, has received a $600,000 Translational Award from the V Foundation for Cancer Research to study chronic lymphocytic leukemia with the aim of developing research models that may help investigators better understand how CLL cells are influenced by new therapies.

11 Nov 2019

Regulating gut bacteria could calm chemo side effects, reduce cognitive problems

In a new study, scientists observed several simultaneous reactions in mice given a common chemotherapy drug: Their gut bacteria and tissue changed, their blood and brains showed signs of inflammation, and their behaviors suggested they were fatigued and cognitively impaired.

11 Nov 2019

'Family Connects' program can reduce the rate of early child abuse investigations

Family Connects, a program where nurses conduct home visits for newborns and their families, is linked to substantial reductions in child maltreatment investigations in children's earliest years, according to new research from Duke University.

11 Nov 2019

New textbook on mysterious and deadly cytokine storm syndrome

There's no telling where the call will come from, or when. But Randy Cron, M.D., Ph.D., professor of pediatrics and medicine at UAB, knows to expect them.

11 Nov 2019

Lupus flare-ups could be linked to environmental factors

Researchers have found that alteration in the environment and atomospheric factors could be associated with organ specific flare-ups of lupus among patients diagnosed with Systemic Lupus Erethematosus (SLE). The study results were presented at the 2019 ACR/ARP Annual Meeting. The abstract was titled, “Environmental and Atmospheric Factors in Systemic Lupus Erythematosus: A Regression Analysis.”

11 Nov 2019

Tocilizumab more effective than rituximab in achieving low disease activity in RA patients

New research discovered that tocilizumab is more effective than rituximab in achieving low disease activity in patients with rheumatoid arthritis whose synovial tissue show a low level of B cell infiltration and did not respond to conventional synthetic disease-modifying anti-rheumatic drugs (conventional synthetic DMARDs) or tumor necrosis factor inhibitors first.

11 Nov 2019

Dengue vaccine from Takeda shows promise

Officials have confirmed the initial success with trials of Dengue vaccine. Dengue, a viral disease borne by mosquitoes is considered to be one of the top ten health threats says the world Health Organization (WHO). Since the beginning of the outbreaks and the hundreds of deaths due to this infection, researchers have been on the lookout for vaccines to prevent this infection.

10 Nov 2019

Atmospheric and environmental changes linked to organ-specific lupus flares

New research findings presented at the 2019 ACR/ARP Annual Meeting found a strong association between changes in atmospheric and environmental variables 10 days before a clinic visit and organ-specific lupus flares in patients with systemic lupus erythematosus.

10 Nov 2019

PERL study: Reducing uric acid levels does not benefit type 1 diabetes patients with kidney disease

Diabetic kidney disease remains one of the most intractable complications of diabetes. Progress has been made using glycemic and blood pressure control, but the search continues for improved treatments for the estimated one in four adults with diabetes who has some level of nephropathy and continues at risk for eventual kidney failure.

10 Nov 2019

Preclinical data on new drug combination to treat neuroblastoma published

Neuroblastoma is the most common cancer outside of the brain in infants and young children and often fails to respond to therapy. Though it can appear in several areas of the body, it commonly develops as a solid tumor most frequently found in or adjacent to the adrenal glands, which sit atop the kidneys.

10 Nov 2019

Simulation-based approach to target epilepsy enters into clinical trial

In what represents a major milestone on the path to clinical application, a novel method to improve outcomes of Epilepsy surgery has now received approval for clinical testing in 13 French hospitals.

9 Nov 2019

Key risk factors, causes of mortality and disability underrepresented in NIH-supported prevention research

A study by National Institutes of Health scientists in the Office of Disease Prevention examined NIH grants and cooperative agreements during fiscal years 2012 through 2017 to determine the alignment of prevention research across NIH institutes and centers with leading risk factors and causes of death and disability in the United States.

8 Nov 2019

Kibow Biotech participates in ASN Kidney Week 2019

Kibow Biotech announces its 15th consecutive year of participation in the ASN Conferences after 22 years as a pioneer in the use of Pro/Prebiotics in people with failing kidneys.

From Kibow Biotech Inc. 8 Nov 2019

New stem cell technology gives new hope for high-risk leukemia patients

Few people get a second chance at life. And fewer still are forced to take it before their 25th birthday. Tyler Rabey is one of those people. He was diagnosed with an aggressive form of leukemia at the prime of his life; a cancer that defied all standard treatments.

8 Nov 2019

Cytel expands its advanced real-world analytics capabilities with acquisition of MTEK Sciences

Cytel Inc., the leading provider of innovative analytical software and consulting services to the biopharmaceutical sector, and a portfolio company of New Mountain Capital, today announced that it has acquired MTEK Sciences to further expand its advanced real-world analytics capabilities.

From Cytel 8 Nov 2019

First device-based, non-drug therapy for treating ADHD in children

Deciding how to treat attention deficit hyperactivity disorder in children can be a difficult decision for parents. Stimulants, such as Adderall and Ritalin, are the most commonly prescribed ADHD treatments - and are considered to be the most effective.

8 Nov 2019

Clinical Trial News and Research

Young male cancer survivors may benefit from testosterone replacement therapy

New study sounds a note of caution in using probiotics in ICU

Scientists identify new mechanism for the development of Parkinson's disease

Researchers uncover new and unexploited drug target for childhood cancer

Rutgers researcher receives $600,000 grant to study chronic lymphocytic leukemia

Regulating gut bacteria could calm chemo side effects, reduce cognitive problems

'Family Connects' program can reduce the rate of early child abuse investigations

New textbook on mysterious and deadly cytokine storm syndrome

Lupus flare-ups could be linked to environmental factors

Tocilizumab more effective than rituximab in achieving low disease activity in RA patients

Dengue vaccine from Takeda shows promise

Atmospheric and environmental changes linked to organ-specific lupus flares

PERL study: Reducing uric acid levels does not benefit type 1 diabetes patients with kidney disease

Preclinical data on new drug combination to treat neuroblastoma published

Simulation-based approach to target epilepsy enters into clinical trial

Key risk factors, causes of mortality and disability underrepresented in NIH-supported prevention research

Kibow Biotech participates in ASN Kidney Week 2019

New stem cell technology gives new hope for high-risk leukemia patients

Cytel expands its advanced real-world analytics capabilities with acquisition of MTEK Sciences

First device-based, non-drug therapy for treating ADHD in children

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