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FDA approves QIAGEN’s therascreen EGFR test as companion diagnostic for NSCLC patients

QIAGEN N.V. (NASDAQ: QGEN; Frankfurt Prime Standard: QIA) today announced it has received approval by the U.S. Food and Drug Administration (FDA) to market the therascreen EGFR test as a companion diagnostic to guide the use of Boehringer Ingelheim's new targeted therapy, GILOTRIF™ (afatinib), for treatment of metastatic NSCLC in patients whose tumors have certain EGFR gene mutations.

From QIAGEN Manchester Limited 15 Jul 2013

C2N Diagnostics, CIL sign collaborative research and global supplier agreement

C2N Diagnostics today announced that it has signed a collaborative research and a global, exclusive supplier agreement with Cambridge Isotope Laboratories, Inc. The partnership guarantees C2N's future access to mass quantities of highly enriched stable isotopes at predictable prices.

12 Jul 2013

PathoQuest closes new fundraising of EUR 3.8 million

PathoQuest, a new generation molecular diagnostics company that offers a new approach based on NGS (Next Generation Sequencing) in the field of infectious diseases, announces today the closing of a new fundraising of EUR 3.8 million.

12 Jul 2013

Study provides clear understanding of breast milk content and its effect on infants' health

Scientists are making strides toward unraveling the surprisingly complex chemistry underpinning that axiom of infant feeding "breast is best," according to an article in the current edition of Chemical & Engineering News.

12 Jul 2013

PrenaTest can be now performed for high risk pregnancies after ninth week

PrenaTest, Europe's first non-invasive molecular genetic blood test to determine fetal trisomies 13, 18 and 21 in the mother's blood can now be performed for high risk pregnancies after the ninth week (W 9 + D 0).

11 Jul 2013

Agreement expands national presence of Cleveland Clinic Laboratories

Cleveland Clinic Laboratories will now be the main provider of specialized testing and diagnostics services for ACL Laboratories, one of the largest hospital system laboratories in the United States.

10 Jul 2013

Infection control program and active surveillance can reduce incidence of impatient C. diff infections

A comprehensive infection control program combined with an active surveillance process significantly reduced the incidence of Clostridium difficile (C. diff) infections in a long-term acute care hospital, according to a study published in the Journal for Healthcare Quality, the peer reviewed publication of the National Association for Healthcare Quality (NAHQ).

10 Jul 2013

Researcher uncover biomarkers from stem cells derived from bone marrow of ALS patients

Amyotrophic Lateral Sclerosis (ALS) is a devastating motor neuron disease that rapidly atrophies the muscles, leading to complete paralysis. Despite its high profile - established when it afflicted the New York Yankees' Lou Gehrig - ALS remains a disease that scientists are unable to predict, prevent, or cure.

10 Jul 2013

FORMA Therapeutics, CRT partner to discover therapeutic drug candidates against DUBs

FORMA Therapeutics and Cancer Research Technology, Ltd., the commercialization company of Cancer Research UK, announced today a bold research initiative to discover innovative tools, technologies and therapeutic drug candidates against a variety of protein homeostasis regulators called, deubiquitinating enzymes.

9 Jul 2013

Atomo Diagnostics, BBI Solutions sign agreement for global rollout out of AtomoRapid test

Medical technology developer Atomo Diagnostics and market leading diagnostic company BBI Solutions have entered into an agreement to commercialise Atomo’s award winning, integrated rapid blood test platform, AtomoRapid.

9 Jul 2013

Leica Biosystems announces acquisition of Kreatech Diagnostics

Leica Biosystems announced that it has acquired Kreatech Diagnostics, a privately-held provider of DNA fluorescent in-situ hybridization probes and target labeling reagents for microarrays.

9 Jul 2013

Researchers discover potential biomarkers that track progression of neurodegenerative disease

A hallmark of neurodegenerative diseases such as Alzheimer's, Parkinson's and Huntington's is that by the time symptoms appear, significant brain damage has already occurred-and currently there are no treatments that can reverse it.

9 Jul 2013

Mouse study identifies new treatment options for bowel cancer

Researchers have discovered the genetic processes that cause specific types of bowel cancer. Using this knowledge, they identified cancer drugs that target these genes. Their findings offer the opportunity to develop personalised treatment based on a person's genetic profile.

9 Jul 2013

BioNano Genomics signs strategic partnership with New York Genome Center

BioNano Genomics and the New York Genome Center announced today a strategic partnership between the two institutions that includes the purchase of an Irys System by NYGC.

8 Jul 2013

Seattle researchers map critical molecules that regulate inflammation during flu infection

The influenza virus' ability to mutate quickly has produced new, emerging strains that make drug discovery more critical than ever. For the first time, researchers at Seattle BioMed, along with collaborators at the University of California, San Diego School of Medicine, St. Jude Children's Research Hospital and the University of Washington, have mapped how critical molecules regulate both the induction and resolution of inflammation during flu infection.

6 Jul 2013

Researchers fabricate nanotweezers that could be used to control and regulate enzymes

In new research, Hao Yan and his colleagues at Arizona State University's Biodesign Institute describe a pair of tweezers shrunk down to an astonishingly tiny scale. When the jaws of these tools are in the open position, the distance between the two arms is about 16 nanometers-over 30,000 times smaller than a single grain of sand.

5 Jul 2013

Collaborative research yields a wiring map on how TB responds to changes in environment

Despite decades of research on the bacterium that causes tuberculosis (TB), scientists have not had a comprehensive understanding of how the bacterium is wired to adapt to changing conditions in the host.

5 Jul 2013

GAPVAC aims to develop personalized therapeutic vaccines for cancer

A highly innovative project supported by a €6 million European Union Framework 7 (EU FP7) program grant to develop a novel class of therapeutic cancer vaccines is now under way.

4 Jul 2013

Study says screening heart with natriuretic peptide may reduce risk of dysfunction, heart failure

Among patients at risk of heart failure, collaborative care based on screening for certain levels of brain-type natriuretic peptide reduced the combined rates of left ventricular systolic dysfunction, diastolic dysfunction, and heart failure as well as emergency cardiovascular hospitalizations, according to a study in the July 3 issue of JAMA.

3 Jul 2013

Prosigna Breast Cancer Prognostic Gene Signature Assay study published in JCO

NanoString Technologies, Inc., a provider of life science tools for translational research and molecular diagnostic products, today announced that the TransATAC clinical validation study for its Prosigna Breast Cancer Prognostic Gene Signature Assay, which is based on the PAM50 gene signature, was published in the Journal of Clinical Oncology.

From NanoString Technologies 2 Jul 2013

Diagnostics News and Research

FDA approves QIAGEN’s therascreen EGFR test as companion diagnostic for NSCLC patients

C2N Diagnostics, CIL sign collaborative research and global supplier agreement

PathoQuest closes new fundraising of EUR 3.8 million

Study provides clear understanding of breast milk content and its effect on infants' health

PrenaTest can be now performed for high risk pregnancies after ninth week

Agreement expands national presence of Cleveland Clinic Laboratories

Infection control program and active surveillance can reduce incidence of impatient C. diff infections

Researcher uncover biomarkers from stem cells derived from bone marrow of ALS patients

FORMA Therapeutics, CRT partner to discover therapeutic drug candidates against DUBs

Atomo Diagnostics, BBI Solutions sign agreement for global rollout out of AtomoRapid test

Leica Biosystems announces acquisition of Kreatech Diagnostics

Researchers discover potential biomarkers that track progression of neurodegenerative disease

Mouse study identifies new treatment options for bowel cancer

BioNano Genomics signs strategic partnership with New York Genome Center

Seattle researchers map critical molecules that regulate inflammation during flu infection

Researchers fabricate nanotweezers that could be used to control and regulate enzymes

Collaborative research yields a wiring map on how TB responds to changes in environment

GAPVAC aims to develop personalized therapeutic vaccines for cancer

Study says screening heart with natriuretic peptide may reduce risk of dysfunction, heart failure

Prosigna Breast Cancer Prognostic Gene Signature Assay study published in JCO

Event guide: 16th Clinical Biomarkers & CDx Summit Europe eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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