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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

EKF secures COVID-19 novel sample collection kit manufacturing and supply contracts

EKF Diagnostics, the global in vitro diagnostics company, announces it has secured new contracts for the manufacture and supply of a novel, patented sample collection device which allows COVID-19 samples to be rapidly inactivated in the collection tube, avoiding contamination and preserving RNA without need for refrigeration.

From EKF Diagnostics 26 May 2020

New genomic method helps obtain high-resolution maps of DNA in the cell nucleus

Researchers at Karolinska Institutet in Sweden have developed a new sequencing method that makes it possible to map how DNA is spatially organised in the cell nucleus - revealing which genomic regions are at higher risk of mutation and DNA damage.

26 May 2020

The infection of lung stem cells may determine SARS-CoV-2 pathogenicity

A group of researchers from Russia and France has demonstrated how stem cells in the lungs can be readily infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), leading to significant defects in their regeneration capacity and more severe coronavirus disease (COVID-19). Their manuscript is currently available on the preprint server bioRxiv.

25 May 2020

Study shows cats can harbor SARS-CoV-2 without any symptoms

A recent paper from Spanish researchers at the Hospital Universitario San Pedro-CIBIR, available on the medRxiv* preprint server, suggests that cats may act as asymptomatic dispersers of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), even though viral transmission from animals to humans still seems highly unlikely.

24 May 2020

Virginia Tech researcher wins $661,216 grant to study Lyme arthritis

With a $661,216 grant from the Steven & Alexandra Cohen Foundation, Brandon Jutras, an assistant professor of biochemistry in the Virginia Tech College of Agriculture and Life Sciences, will study Lyme arthritis, including the cellular component that contributes to it.

22 May 2020

Changes in antibodies and RNA shedding during early SARS-CoV-2 infection

As the COVID-19 pandemic and its far-reaching implications continue to unfold globally and disrupt our normal way of life, scientists and researchers are racing to find an appropriate vaccine or therapeutic drug. This process involves understanding how the virus interacts with the host cell, the dynamics of the host immune response, and the eventual outcome.

22 May 2020

Study evaluates the effectiveness of interferon beta 1b in COVID-19 pneumonia

As the world struggles to overcome the current COVID-19 pandemic with non-pharmacological interventions, in the absence of an effective drug or vaccine, existing immunomodulators are being repurposed. A new study published on the preprint server medRxiv* in May 2020 shows no clinical benefit to the use of one such drug, called interferon beta 1b (IFN beta1b).

22 May 2020

Researchers analyze data on RNA structure of tick-borne encephalitis virus

Researchers from Sechenov University together with colleagues from several Russian institutes analyzed data on the RNA structure of tick-borne encephalitis virus.

22 May 2020

Prediction of incubation period for COVID-19 and other viruses

A new study published on the preprint server bioRxiv* in May 2020 provides a method to estimate the incubation period for any new pathogen, which could help to define the optimal quarantine period necessary to keep the spread of the causative agent in check.

22 May 2020

Novel tool helps translate complex communication between microbes and the body

A new tool developed by scientists at the Quadram Institute and Earlham Institute is helping to translate the complex communication between the microbiome and the body.

21 May 2020

Mutations in SARS-CoV-2 may explain its dominance and spread

Researchers at Dokuz Eylül University, Turkey, have identified mutations in the genome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that may have contributed to its dominance in Europe and elsewhere.

21 May 2020

COVID-19 in farmed Mink in the Netherlands

A new study published on the preprint server bioRxiv in May 2020 reports the development of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in farmed mink in two locations in the Netherlands.

21 May 2020

Research demonstrates self-synthesis and assembly of 30S subunit of ribosome

As the cell's protein factory, the ribosome is the only natural machine that manufactures its own parts. That is why understanding how the machine, itself, is made, could unlock the door to everything from understanding how life develops to designing new methods of drug production.

21 May 2020

Analysis: Get ready for the vaccine — they’re never simple

If there is a silver lining to the flawed U.S. response to the coronavirus pandemic, it is this: The relatively high number of new cases being diagnosed daily — upward of 20,000 — will make it easier to test new vaccines.

21 May 2020

Saliva testing allows quick, accurate and non-invasive SARS-CoV-2 detection

Saliva is one of the ways people can transmit the novel coronavirus to others, but it may also help combat coronavirus disease (COVID-19). Scientists are now looking into using saliva to test for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent for COVID-19 disease.

20 May 2020

Experts urge further improvements in COVID-19 testing to increase speed and availability

In an important, comprehensive, and timely review, an expert team from the University of California Berkeley details the methodologies used in nucleic acid-based tests for detecting the presence of SARS-CoV-2, the virus that causes COVID-19.

20 May 2020

Researchers highlight the need to revise the protocol for detecting ZIKV infection in placenta

Shortly after the explosion in microcephaly cases caused by Zika virus in Brazil in 2015-16, several scientific studies were published with evidence that the pathogen is capable of crossing the human placenta, the organ that keeps the fetus connected to the mother's body during pregnancy.

20 May 2020

Main receptors used by SARS-CoV-2 for cell entry are absent in the human placenta

Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is unlikely to infect human placenta through the canonical cell entry mediators, Wayne State University researchers showed that other interacting proteins may still play an important role during the viral infection. The study is currently available on the preprint server bioRxiv.

20 May 2020

'Senolytic' therapy blunts liver tumor progression in animal models

"Senotherapy," a treatment that uses small molecule drugs to target "senescent" cells, or those cells that no longer undergo cell division, blunts liver tumor progression in animal models according to new research from a team led by Celeste Simon, Ph.D., a professor of Cell and Developmental Biology in the Perelman School of Medicine at the University of Pennsylvania and scientific director of the Abramson Family Cancer Research Institute.

20 May 2020

Moderna’s coronavirus vaccine candidate shows promise in phase I trial

Moderna, who partnered with the National Institutes of Health, announced that its candidate vaccine appeared to be safe when administered to eight healthy volunteers. The vaccine also stimulated an immune response to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes the coronavirus disease (COVID-19).

20 May 2020