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Advanced pancreatic cancer model more accurately depicts PDAC tumor progression

Pancreatic ductal adenocarcinoma (PDAC), is highly aggressive and lethal. It is the most prevalent type of pancreatic cancer, making up 90% of cases; it also has a high rate of metastasis, with an average five-year survival rate of less than 10%.

29 Mar 2023

People with allergic diseases may be at heightened risk of osteoarthritis

People with atopic (allergic) diseases like asthma or eczema may be at heightened risk of the painful and often disabling joint condition, osteoarthritis, finds research published online in the Annals of the Rheumatic Diseases.

29 Mar 2023

Newly designed molecule disrupts the infection mechanism of SARS-CoV-2

A team of scientists led by the Department of Energy's Oak Ridge National Laboratory designed a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and other viral diseases.

28 Mar 2023

Study: Efforts to track HIV and HCV incidence among people who inject drugs need to be intensified

Countries must intensify efforts to track HIV and hepatitis C virus (HCV) incidence among people who inject drugs, and to prioritize this group in prevention and elimination work, according to new University of Bristol-led research, published online in The Lancet Gastroenterology & Hepatology.

28 Mar 2023

The rise of Candida auris: Understanding its origin and persistence

In a recent study published in the PLOS Pathogens journal, researchers from the University of Texas Health Science Center at San Antonio in the United States (US) explored the existing perspectives on the origination, resistance, and transmission of Candida auris, a human fungal pathogen.

28 Mar 2023

People with asthma or eczema more likely to develop osteoarthritis

Stanford Medicine scientists and their colleagues have found that having asthma or eczema increases the likelihood of developing osteoarthritis — signaling that there may be an allergic pathway that can be targeted with existing drugs.

28 Mar 2023

3D cell culture system tests how inhibiting fibroblast activities can help treat lung cancer

Fibroblasts build and maintain the extracellular matrix, or physical scaffolding for cells, in the connective tissues within the body.

28 Mar 2023

New combination therapy shows promising results in some patients with advanced head and neck cancer

A new combination drug treatment showed promising results in patients with pan-refractory, recurrent/metastatic head and neck cancer, according to a study published today in the Journal of Clinical Oncology.

28 Mar 2023

New molecule slows the effects of one of SARS-CoV-2's more dangerous components

Researchers have designed a molecule that slows the effects of one of SARS-CoV-2's more dangerous components – an enzyme called a protease that cuts off the immune system's communications and helps the virus replicate.

28 Mar 2023

Nuclear medicine brain imaging can help evaluate the biological changes that cause chemo-brain

A newly published literature review sheds light on how nuclear medicine brain imaging can help evaluate the biological changes that cause chemotherapy-related cognitive impairment (CRCI), commonly known as chemo-brain.

28 Mar 2023

NIH scientists discover an autoinflammatory disease caused by mutations in the LYN gene

Scientists have identified an autoinflammatory disease caused by mutations in the LYN gene, an important regulator of immune responses in health and disease.

28 Mar 2023

CBD-based compounds boost the effects of naloxone

There's been a recent push in the U.S. to make naloxone - a fast-acting opioid antidote - available without a prescription.

28 Mar 2023

Newly found strategy used by metastasized tumors may explain why some promising immunotherapies fail

Cancer that has spread to areas like the lungs can apply the brakes to a natural pathway that should recruit killer T cells directly to where it has metastasized, scientists report.

28 Mar 2023

Avacta appoints Karen Harrison as Chief Operating Officer for Therapeutics Division

Avacta Group plc today announced the appointment of Karen Harrison as Chief Operating Officer of its Therapeutics Division.

From Avacta Life Sciences Ltd. 28 Mar 2023

Surgeons can play an important role in reducing breast cancer disparities

Surgeons can play a key role in reducing breast cancer disparities by increasing their awareness of where disparities exist and having open conversations with their patients about their needs to initiate referrals early on in their care, according to a new collective review article published in the Journal of the American College of Surgeons.

28 Mar 2023

Truly random drug testing: ADHD patients face uneven urine screens and, sometimes, stigma

Some adults who take prescription medication for attention-deficit/hyperactivity disorder are required to have their urine tested for drugs several times a year. Others never are tested.

28 Mar 2023

Researchers receive NCI grant to advance new treatment approach for pancreatic cancer

Cosimo Commisso, Ph.D., and Susanne Heynen-Genel, Ph.D., have received a grant from the National Cancer Institute to advance a new treatment approach for pancreatic cancer.

27 Mar 2023

Developers of gene therapies can utilize FDA guidance to prepare ODD or RPDD applications

Providing an overview of the submissions process and examples of U.S. Food and Drug Administration (FDA) applications for Orphan Drug Designation (ODD) and Rare Pediatric Disease Designation (RPDD), a new article can help developers of gene therapies for rare genetic diseases.

27 Mar 2023

Myeloid cells can harbor HIV in people taking antiretroviral therapy

A subset of white blood cells, known as myeloid cells, can harbor HIV in people who have been virally suppressed for years on antiretroviral therapy, according to findings from a small study supported by the National Institutes of Health.

27 Mar 2023

Targeting the STING pathway with a combination strategy promotes antitumor activity

Immunotherapies have greatly improved the outcomes of many patients with melanoma. But there is still a need for new approaches for the subset of patients who do not respond well to this type of therapy.

27 Mar 2023

Drugs News and Research

Advanced pancreatic cancer model more accurately depicts PDAC tumor progression

People with allergic diseases may be at heightened risk of osteoarthritis

Newly designed molecule disrupts the infection mechanism of SARS-CoV-2

Study: Efforts to track HIV and HCV incidence among people who inject drugs need to be intensified

The rise of Candida auris: Understanding its origin and persistence

People with asthma or eczema more likely to develop osteoarthritis

3D cell culture system tests how inhibiting fibroblast activities can help treat lung cancer

New combination therapy shows promising results in some patients with advanced head and neck cancer

New molecule slows the effects of one of SARS-CoV-2's more dangerous components

Nuclear medicine brain imaging can help evaluate the biological changes that cause chemo-brain

NIH scientists discover an autoinflammatory disease caused by mutations in the LYN gene

CBD-based compounds boost the effects of naloxone

Newly found strategy used by metastasized tumors may explain why some promising immunotherapies fail

Avacta appoints Karen Harrison as Chief Operating Officer for Therapeutics Division

Surgeons can play an important role in reducing breast cancer disparities

Truly random drug testing: ADHD patients face uneven urine screens and, sometimes, stigma

Researchers receive NCI grant to advance new treatment approach for pancreatic cancer

Developers of gene therapies can utilize FDA guidance to prepare ODD or RPDD applications

Myeloid cells can harbor HIV in people taking antiretroviral therapy

Targeting the STING pathway with a combination strategy promotes antitumor activity

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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