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Certain blood thinners may increase risk of bleeding in CKD patients

Certain blood thinners approved to treat atrial fibrillation may put patients with chronic kidney disease at a higher risk of bleeding, according to the results of a study in an upcoming issue of the Clinical Journal of the American Society of Nephrology.

13 Jul 2018

UCLA researchers uncover gene that controls equilibrium of bone and fat in bone marrow

In an unexpected discovery, UCLA researchers have found that a gene previously known to control human metabolism also controls the equilibrium of bone and fat in bone marrow as well as how an adult stem cell expresses its final cell type.

13 Jul 2018

Sodium nitroprusside treatment prevents schizophrenia symptoms in animal model

Researchers at the Federal University of São Paulo in Brazil have tested a treatment with sodium nitroprusside in a strain of rats that spontaneously develop some of the symptoms associated with schizophrenia.

12 Jul 2018

Fighting cancer with engineered cancer cells

Researchers at Brigham and Women's Hospital have engineered cancer cells that track and kill cancer cells. The modified cancer cells have demonstrated anti-cancer efficacy in preclinical studies, destroying both primary and metastatic tumours.

12 Jul 2018

Molecular insights of NagA enzyme could help combat TB

Research by a team led by Dr Elizabeth Fullam, has revealed new findings about an enzyme found in Mycobacterium tuberculosis the bacterium that causes TB.

12 Jul 2018

Researchers uncover molecular drivers of a deadly pediatric cancer

Researchers have made important discoveries about the molecular mechanisms driving acute myeloid leukemia (AML), a deadly pediatric cancer.

11 Jul 2018

Study elucidates pathophysiology of systemic lupus erythematosus

Osaka University researchers elucidated the pathophysiology of systemic lupus erythematosus, an autoimmune disorder that causes inflammation and tissue damage.

11 Jul 2018

Researchers develop biofilm formulations that protect from necrotizing enterocolitis

Most of the time, we think biofilms are bad news. And when pathogenic microbes form biofilms, they are.

11 Jul 2018

Promoting health equity by understanding cancer risk and outcomes

Aiming to reduce cancer risk, improve the understanding of cancer outcomes, and promote cancer health equity in our most vulnerable populations at the community level, the Rutgers School of Public Health and Rutgers Cancer Institute of New Jersey have recruited Anita Y. Kinney, PhD, as Director of the Center of Cancer Health Disparities at the Rutgers School of Public Health and Associate Director of Cancer Health Equity and Engagement at Rutgers Cancer Institute.

11 Jul 2018

Newly discovered nanobody holds promise to advance targeted therapies for several diseases

Researchers from Case Western Reserve University School of Medicine have found a nanobody that holds promise to advance targeted therapies for a number of neurological diseases and cancer.

10 Jul 2018

Mice study shows promise for treating genetic conditions during fetal development

Researchers at Carnegie Mellon University and Yale University have for the first time used a gene editing technique to successfully cure a genetic condition in a mouse model.

10 Jul 2018

New trial to evaluate whether fasting can improve MS symptoms

People with multiple sclerosis (MS) can find an abundance of conflicting advice suggesting that special diets – everything from avoiding processed foods to going low-carb – will ease their symptoms. But the evidence is scanty that dietary changes can improve fatigue or other MS symptoms.

10 Jul 2018

Study uncovers how a sticky protein promotes activity of estrogen in breast cancer cells

New research uncovers how a sticky protein called fibronectin promotes the activity of estrogen in breast cancer cells.

9 Jul 2018

Study offers new hope for people with disabling Dupuytren's disease

Researchers at the Kennedy Institute and Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, working with clinicians at NHS Lothian, have found that injection of the anti-TNF drug adalimumab into Dupuytren's disease nodules results in the reduction of the cell characteristics responsible for progression of Dupuytren's disease.

9 Jul 2018

Researchers discover critical link in mapping recurrent mutations of melanoma

A critical link in mapping recurrent mutations of melanoma -- the most serious form of skin cancer in humans -- has been discovered by researchers at Washington State University School of Molecular Biosciences, in collaboration with researchers at Georgia State University.

6 Jul 2018

Single-cell RNA sequencing reveals how complex brain circuit works

The complexity of the human brain presents scientists with immense challenges as they try to find new treatments for a host of diseases and conditions. But the advent of a new technology known as single-cell RNA sequencing is opening a window into how the brain works.

6 Jul 2018

Cleara Biotech creates three public-private partnerships to discover and develop new therapeutics

Cleara Biotech B.V., a Netherlands-based biopharmaceutical company, announced today the creation of three public-private partnerships to discover and develop new therapeutics.

6 Jul 2018

Researchers develop ingestible sensor to non-invasively monitor indicators of disease

NIBIB-funded researchers at the Massachusetts Institute of Technology have created an ingestible sensor to non-invasively monitor indicators of disease in the stomach and intestines.

6 Jul 2018

Research sheds light on composition of cannabis used to treat children with epilepsy

A pioneering study has found Australian parents who turned to medicinal cannabis to treat children with epilepsy overwhelmingly (75 percent) considered the extracts as "effective". Contrary to parental expectations, extracts generally contained low doses of cannabidiol - commonly considered to be a key therapeutic element and that has been successfully used in recent clinical trials to treat epilepsy.

5 Jul 2018

Researchers discover genetic marker associated with salt sensitivity of blood pressure

For the first time researchers have identified a genetic marker (GNAI2) that is associated with the risk of salt sensitivity in blood pressure regardless of age or gender.

5 Jul 2018

Therapeutics News and Research

Certain blood thinners may increase risk of bleeding in CKD patients

UCLA researchers uncover gene that controls equilibrium of bone and fat in bone marrow

Sodium nitroprusside treatment prevents schizophrenia symptoms in animal model

Fighting cancer with engineered cancer cells

Molecular insights of NagA enzyme could help combat TB

Researchers uncover molecular drivers of a deadly pediatric cancer

Study elucidates pathophysiology of systemic lupus erythematosus

Researchers develop biofilm formulations that protect from necrotizing enterocolitis

Promoting health equity by understanding cancer risk and outcomes

Newly discovered nanobody holds promise to advance targeted therapies for several diseases

Mice study shows promise for treating genetic conditions during fetal development

New trial to evaluate whether fasting can improve MS symptoms

Study uncovers how a sticky protein promotes activity of estrogen in breast cancer cells

Study offers new hope for people with disabling Dupuytren's disease

Researchers discover critical link in mapping recurrent mutations of melanoma

Single-cell RNA sequencing reveals how complex brain circuit works

Cleara Biotech creates three public-private partnerships to discover and develop new therapeutics

Researchers develop ingestible sensor to non-invasively monitor indicators of disease

Research sheds light on composition of cannabis used to treat children with epilepsy

Researchers discover genetic marker associated with salt sensitivity of blood pressure

Advancing therapeutic biopolymer development eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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