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A prediction rule for disease outcome in patients with recent-onset undifferentiated arthritis

Marked by chronic inflammation of the joints and tissue, rheumatoid arthritis (RA) is a painful and potentially disabling autoimmune disease.

30 Jan 2007

Giving birth to a child naturally increases risk of hemorrhage in newborns

The first researchers to use magnetic resonance imaging (MRI) to study the brains of a large group of babies soon after birth found a small amount of bleeding in and around the brains of one in four babies who were delivered vaginally.

30 Jan 2007

Value based insurance design

Like a one-size-fits-all shirt that doesn't fit anyone very well, American health insurance plans charge every person the same out of pocket cost for medical services - regardless of their effect on a person's health.

30 Jan 2007

Stroke treatment helps victims recover brain function

A small but significant study in the U.S. has found that a treatment which was designed to clear blocked carotid arteries and prevent stroke has also improved brain function.

29 Jan 2007

Thailand the latest drug patent buster

Thailand's military government has used World Trade Organization (WTO) rules regarding intellectual property, to allow the sale of generic versions of two important drugs used to treat HIV/AIDS and heart disease.

29 Jan 2007

Gene produces springy protein keeping nerve cells flexible

If you bend a knee or an elbow, the nerves in your limbs stretch but do not break. A University of Utah study suggests why: A gene produces a springy protein that keeps nerve cells flexible. When the gene was disabled in tiny nematode worms, their nerve cells literally broke.

29 Jan 2007

Dll4 signalling through Notchi regulates formation of tip cells during angiogenesis

All tissues, sick and healthy alike, need a blood supply to survive and grow. The key to many medical problems, like preventing tumour development, is therefore to obstruct the spread of the blood vessels. Research scientists at Karolinska Institutet have now discovered a heretofore unknown mechanism for how the body links together its blood vessels.

29 Jan 2007

Photoprinted paper supports simultaneous microscale diagnostic tests

Prototype for a new class of inexpensive, highly practical rapid tests that can be used to carry out several biological tests simultaneously on a single drop.

29 Jan 2007

New mobile application for weight control

A Finnish research group with participants from VTT Technical Research Centre of Finland, the University of Tampere and Nokia Research Center has developed a new personal health diary for the mobile phone.

29 Jan 2007

Nanocarrier stimuli-activated gene delivery

One approach to developing tumor-specific drug delivery agents is to create nanomaterials that release a therapeutic payload only after reaching their intended target.

29 Jan 2007

New drug to treat kidney failure during septic shock

Research from Melbourne's Howard Florey Institute and the Austin Hospital has resulted in a drug to treat kidney failure during septic shock, which will be trialled at the Austin Hospital from mid-2007.

29 Jan 2007

China should own up to past HIV/AIDS mistakes

Although China in recent years "has made bold strides in its response to HIV/AIDS," the number of new HIV/AIDS cases will continue to increase unless the country "owns up to past mistakes, encourages and supports civil society involvement, and proactively deals with the serious challenges of stigma and misinformation".

29 Jan 2007

Sequenom and Lenetix to develop Rhesus D prenatal diagnostic

Sequenom, Inc. and Lenetix Medical Screening Laboratory, Inc., a provider of rapid genetic screening and diagnostic testing for clinicians worldwide, today announced that they have entered into a collaboration and license agreement to develop and commercialize a proprietary non-invasive prenatal Rhesus D (RhD) incompatibility test based on Sequenom patent rights and RT PCR methodology.

29 Jan 2007

FoxOs shown to be potential new targets for cancer drugs

In an elegant, multiple-gene knockout experiment, a team of Boston scientists has discovered that a trio of molecules, called FoxOs, are fundamentally critical in preventing some cancers, maintaining blood vessel stability, and in keeping blood-forming stem cells healthy.

29 Jan 2007

North American Menopause Society releases guidelines saying HRT beneficial for younger women

The North American Menopause Society on Thursday released a revised position statement that said the benefits of short-term hormone replacement therapy for treatment of menopausal women likely outweigh the risks for younger women, the Wall Street Journal reports.

28 Jan 2007

A plasminogen-activating protease specifically controls the development of primary pneumonic plague

The deadly attack of the bacterium that causes pneumonic plague is significantly slowed when it can't make use of a key protein, scientists at Washington University School of Medicine in St. Louis report in Science.

28 Jan 2007

Alternative to artery-clogging trans fats

Alejandro's research group found a way to mix oil, water, monoglycerides and fatty acids to form a gel substance that provides the same structural and functional benefits as trans and saturated fats.

28 Jan 2007

Linemen more than twice as likely as other players to have metabolic syndrome

After retirement, National Football League (NFL) linemen - generally the heaviest players - are more than twice as likely as other players to have a syndrome that puts them at risk for heart disease, stroke and other cardiovascular diseases

28 Jan 2007

Small molecule targets weak mRNA

A new strategy for fighting cancer aims to make its genes get lost in translation, according to a report in the January 26, 2007, issue of the journal Cell.

28 Jan 2007

New prognostic instrument improves prediction of stroke risk after TIA

The existing prognostic scores for early-risk stroke prediction after transient ischaemic attack (TIA have been validated and refined to develop a unified score that is more predictive than previous methods, according to an Article published in this week's issue of The Lancet.

28 Jan 2007