Antidepressant News and Research

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Antidepressants are medicines that treat depression. Your doctor can prescribe them for you. They can improve your mood, sleep, appetite and concentration. It may take several weeks for them to help. There are several types of antidepressants. You and your doctor may have to try several before finding what works best for you.

Arthritis drug increases effectiveness of antidepressants in bipolar patients

Giving severely depressed patients the arthritis drug celecoxib (Celebrex) dramatically boosted the effectiveness of their antidepressant medication, a Loyola study has found.

10 Nov 2016

MIT researchers develop imaging technique that provides unprecedented view of serotonin dynamics

Serotonin is a neurotransmitter that's partly responsible for feelings of happiness and for mood regulation in humans.

21 Oct 2016

Anti-inflammatory drugs may improve severity of depressive symptoms, study finds

Anti-inflammatory drugs similar to those used to treat conditions such as rheumatoid arthritis and psoriasis could in future be used to treat some cases of depression, concludes a review led by the University of Cambridge, which further implicates our immune system in mental health disorders.

18 Oct 2016

Study links repeated SSRIs during pregnancy to childhood language disorders

The use of selective serotonin reuptake inhibitors at least twice during pregnancy may be associated with an increased risk of offspring developing a speech and/or language disorder, according to a study from Columbia University.

13 Oct 2016

UCLA-led study to evaluate treatment strategies for older adults with depression

More than half of older adults who are treated for depression find that eventually their treatments are no longer effective. When depression persists, these people are at greater risk of accelerated aging, declining mental health and even suicide.

6 Oct 2016

Scientists identify new pathway in the brain that can be targeted to alleviate depression

Northwestern Medicine scientists have discovered a new pathway in the brain that can be manipulated to alleviate depression. The pathway offers a promising new target for developing a drug that could be effective in individuals for whom other antidepressants have failed.

5 Oct 2016

Alcohol produces same neural and molecular changes as rapid antidepressant drugs

Can having a few drinks help people with clinical depression feel better? Yes. At least in terms of biochemistry.

28 Sep 2016

Common genetic variant reduces neurobiological benefits of exercise in mice

A new study revealed that a common genetic variant in the brain-derived neurotrophic factor gene reduces the neurobiological benefits induced by physical exercise in mice.

21 Sep 2016

Mice study explains why antidepressants don't work in some patients

SSRI antidepressants (Selective Serotonin Reuptake Inhibitors, the best known being Prozactm) are amongst the most commonly taken medicines.

20 Sep 2016

Short talk with knowledgeable nurse could help smokers quit cigarettes

A short talk with a knowledgeable nurse could be the difference between a smoker stopping for cigarettes or stopping for nicotine gum on her way home from the hospital.

16 Sep 2016

UAB researchers find microRNA as potential therapeutic target for MDD

A tiny RNA appears to play a role in producing major depression, the mental disorder that affects as many as 250 million people a year worldwide.

9 Sep 2016

Component of general anesthetic shows improvement in patients with treatment-resistant depression

A new study in Biological Psychiatry reports that esketamine, a component of the general anesthetic ketamine, shows rapid and significant improvement in depressive symptoms in patients who do not respond to currently available therapies.

8 Sep 2016

Risk for depression appears to be higher in first three months after stroke, study finds

During the first three months after stroke, the risk for depression was eight times higher than in a reference population of people without stroke, according to an article published online by JAMA Psychiatry.

8 Sep 2016

Study shows adequate sleep may accelerate antidepressant treatment response

Medication is an important part of treatment for many patients with major depressive disorder, but the transition to antidepressants isn't always smooth.

7 Sep 2016

Beta-blockers can help treat bone loss caused by antidepressants in mice

The antidepressant fluoxetine causes bone loss by instructing the brain to send out signals that increase bone breakdown, but a beta-blocker can intercept the signals, a new study in mice has found.

7 Sep 2016

New study suggests most American adults with depression receive no treatment

New findings suggest that most Americans with depression receive no treatment, while raising the possibility that overtreatment of depression is also widespread.

29 Aug 2016

New synthetic methods facilitate development of bioactive and chemical compounds

A new research, affiliated with UNIST has been highlighted on the inside front cover of the June issue of the prestigious journal Chemical Communications.

26 Aug 2016

Study suggests structural changes in the brain help cope with stressful situations

People who experience job loss, divorce, death of a loved one or any number of life's upheavals often adopt coping mechanisms to make the situation less traumatic.

25 Aug 2016

Researchers discover new role of cellular signaling molecule involved in release of hunger hormone

Researchers at UT Southwestern Medical Center have identified a previously unknown role of a cellular signaling molecule involved in release of the "hunger hormone" ghrelin, a finding that could have implications for optimal treatment of children taking beta blockers.

23 Aug 2016

Treating metabolic abnormalities may improve symptoms in patients with treatment-resistant depression

Identifying and treating metabolic deficiencies in patients with treatment-resistant depression can improve symptoms and in some cases even lead to remission, according to new research from the University of Pittsburgh School of Medicine published online today in the American Journal of Psychiatry.

12 Aug 2016