Hematology News and Research

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Hematology, also spelled haematology, is the branch of biology (physiology), pathology, clinical laboratory, internal medicine, and pediatrics that is concerned with the study of blood, the blood-forming organs, and blood diseases. Hematology includes the study of etiology, diagnosis, treatment, prognosis, and prevention of blood diseases.

New protein variant underlies the ability of gastric cancers to resist chemotherapy

A new protein variant underlies the ability of gastric cancers to resist an otherwise effective family of chemotherapy drugs, according to a study by a multidisciplinary team at Weill Cornell Medicine. The results suggest a treatment strategy that could improve the prognoses of many patients with cancer.

6 Dec 2021

DNA sequencing of residual disease accurately identifies leukemia patients who would relapse

In pediatric and young adult patients with acute lymphoblastic leukemia (ALL) treated with tisagenlecleucel (Kymriah), DNA sequencing-based detection of residual disease between three and 12 months accurately identified all patients who would eventually relapse, while other methods were less predictive.

1 Dec 2021

Childhood cancer diagnosis not delayed in Canada during the pandemic, study says

During the first 9 months of the COVID-19 pandemic, researchers did not find a significant difference in the number of new cancer diagnoses in Canadian children compared with before the pandemic, according to a study published in CMAJ.

29 Nov 2021

SPORE-funded Kidney Cancer Program at UT Southwestern reports wide array of tumor models to date

Funded by a Specialized Program of Research Excellence award from the National Cancer Institute (NCI), the Kidney Cancer Program at UT Southwestern's Harold C. Simmons Comprehensive Cancer Center reports the largest and most diverse catalog of kidney cancer tumor models to date.

29 Nov 2021

CIRM awards $4.1 million to advance CAR T-cell therapy from the lab to clinic

On November 23, 2021, the California Institute for Regenerative Medicine (CIRM) governing board approved a $4.1 million grant to enable University of California San Diego School of Medicine researchers to advance a new chimeric antigen receptor (CAR) T-cell therapy from the laboratory into the clinic.

24 Nov 2021

AI identifies patterns on CT scans that offer new promise for treating small cell lung cancer

Researchers at the Center for Computational Imaging and Personalized Diagnostics at Case Western Reserve University have used artificial intelligence (AI) to identify patterns on computed tomography (CT) scans that offer new promise for treating patients with small cell lung cancer.

23 Nov 2021

Liver cancer can be recognized by RNA fragments in saliva and blood

RUDN University doctors examined markers of liver cancer and found that the disease can be recognized by RNA fragments in saliva and blood. The results are published in Oncotarget.

23 Nov 2021

New trial demonstrates stable coagulation factor VIII in hemophilia A patients after gene therapy

A novel gene therapy for hemophilia A led to sustained expression of the clotting factor those patients lack, resulting in a reduction – or in some cases complete elimination – of painful and potentially life-threatening bleeding events, according to a new study led by researchers at Children's Hospital of Philadelphia.

18 Nov 2021

Short-term severe calorie restriction safe, feasible, and well tolerated by cancer patients

A diet involving short-term, severe calorie restriction was safe, feasible, and resulted in a decrease of blood glucose and growth factor concentration, reduction in peripheral blood immunosuppressive cells, and enhanced intratumor T-cell infiltration in cancer patients receiving standard-of-care therapy, according to the results of a clinical trial.

18 Nov 2021

COVID-19 booster shot extremely beneficial for most cancer patients

Most cancer patients who had no measurable immune response after being fully vaccinated for COVID-19 were helped by a third vaccine dose, according to a new study by investigators at the Montefiore Einstein Cancer Center.

16 Nov 2021

Oncologists use immunotherapy at faster rates for trial-ineligible patients, study finds

Cancer patients who are ineligible for clinical trials receive immune checkpoint inhibitors (ICI) at greater rates than patients who are trial eligible despite no survival benefit, according to a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania.

9 Nov 2021

Arginine treatment enhances effectiveness of radiation therapy in cancer patients with brain metastases

Treatment with arginine, one of the amino-acid building blocks of proteins, enhanced the effectiveness of radiation therapy in cancer patients with brain metastases, in a proof-of-concept, randomized clinical trial from investigators at Weill Cornell Medicine and Angel H. Roffo Cancer Institute.

7 Nov 2021

$2.1 million gift will support the development of Dean-Hertzberg Breast Cancer Database System

In an important step that could help answer research questions about breast cancer and develop more personalized solutions for patients, philanthropists Richard and Carol Dean Hertzberg have committed $2.1 million to develop and maintain the Dean-Hertzberg Breast Cancer Database System (BCDS) at Moores Cancer Center at UC San Diego Health.

29 Oct 2021

New approach to control the hierarchical assembly of protein pathways with DNA

Northwestern investigators have identified a novel approach to control the hierarchical assembly of protein pathways with DNA, according to a study published the Proceedings of the National Academy of Sciences.

29 Oct 2021

Study reveals dual role of anti-cancer inhibitor

TG2, an enzyme known to help cancers spread more quickly, also plays a role in regulating T-cells, according to a Northwestern Medicine study published in the Journal for Immunotherapy of Cancer.

21 Oct 2021

Yale Cancer Center receives $6.5 million NIH grant for cellular senescence research

The National Institutes of Health has awarded a grant to fund cellular senescence research in lymphoid organs at Yale Cancer Center.

21 Oct 2021

Interferon treatment coupled with bone marrow transplant reduces risk of leukemia recurrence

Researchers at the University of Michigan Health Rogel Cancer Center have identified a drug that, when given along with a bone marrow transplant, drops the risk of leukemia recurring by 20% among the high-risk patients.

21 Oct 2021

Kidney cancer study provides new insights into tumor invasion and metastatic competence

How cancers metastasize remains poorly understood. The process begins when cancer cells break off from a tumor and invade blood and lymphatic vessels, the body's alleyways. But studying invasion - typically a microscopic process - is challenging.

20 Oct 2021

Underexpression of specific metabolic enzyme is a common feature in kidney cancer, study shows

A team of investigators has discovered that the underexpression of a specific metabolic enzyme is a common and adverse epigenetic modulating feature in clear cell renal cell carcinoma (ccRCC), according to a recent study published in Proceedings of the National Academy of Sciences.

20 Oct 2021

New findings may help widen therapeutic interventions for B-cell acute lymphoblastic leukemia

A retrospective study led by Northwestern Medicine investigators found that the chimeric antigen receptor (CAR) T-cell immunotherapy drug tisagenlecleucel demonstrated safety and efficacy in pediatric patients with relapsed and refractory B-cell acute lymphoblastic leukemia (B-cell ALL), even when the drug doesn't meet the FDA's strict manufacturing standards.

19 Oct 2021

Hematology News and Research

Further Reading

New protein variant underlies the ability of gastric cancers to resist chemotherapy

DNA sequencing of residual disease accurately identifies leukemia patients who would relapse

Childhood cancer diagnosis not delayed in Canada during the pandemic, study says

SPORE-funded Kidney Cancer Program at UT Southwestern reports wide array of tumor models to date

CIRM awards $4.1 million to advance CAR T-cell therapy from the lab to clinic

AI identifies patterns on CT scans that offer new promise for treating small cell lung cancer

Liver cancer can be recognized by RNA fragments in saliva and blood

New trial demonstrates stable coagulation factor VIII in hemophilia A patients after gene therapy

Short-term severe calorie restriction safe, feasible, and well tolerated by cancer patients

COVID-19 booster shot extremely beneficial for most cancer patients

Oncologists use immunotherapy at faster rates for trial-ineligible patients, study finds

Arginine treatment enhances effectiveness of radiation therapy in cancer patients with brain metastases

$2.1 million gift will support the development of Dean-Hertzberg Breast Cancer Database System

New approach to control the hierarchical assembly of protein pathways with DNA

Study reveals dual role of anti-cancer inhibitor

Yale Cancer Center receives $6.5 million NIH grant for cellular senescence research

Interferon treatment coupled with bone marrow transplant reduces risk of leukemia recurrence

Kidney cancer study provides new insights into tumor invasion and metastatic competence

Underexpression of specific metabolic enzyme is a common feature in kidney cancer, study shows

New findings may help widen therapeutic interventions for B-cell acute lymphoblastic leukemia

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

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