Hepatology News and Research

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Hepatology is the branch of medicine that incorporates study of liver, gallbladder, biliary tree and pancreas as well as management of their disorders.

Targeted therapy may increase overall survival in patients with pancreatic cancer

Results from 46 patients given treatments that target specific molecular changes in tumor cells suggest that these therapies could help patients with pancreatic cancer whose tumors harbor those changes survive an extra year.

2 Mar 2020

New imaging method allows scientists to view key part of the colon in 3D

In a groundbreaking discovery, researchers at Children's Hospital of Philadelphia developed a new imaging method that allows scientists to view the enteric nervous system - a key part of the human colon - in three dimensions by making other colon cells that normally block it invisible.

27 Feb 2020

$Investigational drug reduces heartburn severity in patients with refractory GERD$

Investigational drug reduces heartburn severity in patients with refractory GERD

An investigational drug that binds bile acids in the stomach can reduce the severity of heartburn symptoms in patients with treatment-resistant gastroesophageal reflux disease (GERD) when combined with a proton pump inhibitor (PPI), a new study suggests.

26 Feb 2020

Ulcerative colitis and a missing microbe in the gut

Ulcerative colitis is a seriously debilitating inflammatory disease of the bowel leading to crippling symptoms that can affect the quality of life severely. Researchers from Stanford University School of Medicine have found in a new study that a missing microbe could be linked to this condition. The study was published today in the latest issue of the journal Cell Host & Microbe.

25 Feb 2020

Prolonged exposure to a pair of antioxidant proteins may fuel liver enlargement

All life is challenged by oxidants -- reactive molecules or compounds that remove electrons from other molecules -- often with adverse effect, commonly referred to as oxidative stress.

25 Feb 2020

Chemical in veggies help heal fatty liver

A new study shows that a compound naturally occurring in a variety of commonly used vegetables as well as being produced by gut microbes is very useful in melting fat away from a fatty liver.

9 Feb 2020

New guidelines recommend no-biopsy approach for childhood celiac disease diagnosis

The European Society for Paediatric Gastroenterology, Hepatology and Nutrition has today issued new guidance to physicians on the diagnosis of celiac disease in children recommending the no-biopsy approach at diagnosis for the majority of children suspected of having the disease.

7 Feb 2020

Study determines prevalence of fatty liver disease and fibrosis among young adults in the UK

One in five young people have fatty liver disease (steatosis), with one in 40 having already developed liver scarring (fibrosis), research published today [15 January] has found.

16 Jan 2020

Study shows how cancer-causing genes promote metastasis

Cancer-promoting genes MYC and TWIST1 co-opt immune system cells to enable cancer cells to spread, but blocking a key step in this process can help prevent the disease from developing.

14 Jan 2020

Classroom activities pose low risk of harmful gluten exposure in children with celiac disease

Common classroom activities – such as playing with Play-Doh or uncooked pasta – have little or no potential to cause harmful gluten exposure in children with celiac disease, reports a study in the Journal of Pediatric Gastroenterology and Nutrition.

7 Jan 2020

Scientists discover potential drug compounds that target common type of liver cancer

Scientists from the Cancer Science Institute of Singapore at the National University of Singapore, and the Agency for Science, Technology and Research (A*STAR)'s Genome Institute of Singapore have discovered four potential drug compounds that target hepatocellular carcinoma, the most common type of liver cancer.

30 Dec 2019

Novel drug from Amazon rainforest tree sap evaluated for treatment of chronic idiopathic diarrhea in non-HIV patients

A drug purified and developed from the sap of a tree in the Amazon rainforest is now being studied for the treatment of chronic idiopathic diarrhea in non-HIV patients at The University of Texas Health Science Center at Houston as part of a two-year pilot study.

16 Dec 2019

New research may help guide future treatment for non-alcoholic fatty liver disease

Edith Cowan University researchers have found that a chronic disease affecting up to 80 per cent of overweight people may be causing an iron deficiency that simply leaves them too tired to get off the couch.

11 Dec 2019

Study explores cost-effectiveness of transient elastography for detecting liver fibrosis

Non-alcoholic fatty liver diseases (NAFLD) and alcohol-related diseases (ALD) are currently the leading cause of chronic disease, cancer and mortality associated with this organ in developed countries.

10 Dec 2019

Young patients with IBD have increased risk of severe viral infections

Young patients with inflammatory bowel disease are five times more likely than the general population to develop viral infections that can lead to hospitalization or permanent organ damage, a new study published in the UEG Journal has found.

5 Dec 2019

New 'virtual biopsy' allows doctors to definitively diagnose cysts in the pancreas

Research from doctors at The Ohio State University Wexner Medical Center finds a new "virtual biopsy" allows them to definitively diagnose cysts in the pancreas with unprecedented accuracy. This means they can eliminate precancerous cysts and potentially save lives.

4 Dec 2019

New human colon-on-a-chip enables in vitro study of mucus physiology

We have a mutualistic but complicated relationship with the collection of microbes in our gut known as the intestinal microbiome.

3 Dec 2019

Key mechanism identified for how antiviral immune responses reprogram liver metabolism

Researchers at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences identified a key mechanism for how antiviral immune responses reprogram liver metabolism. Their recent study, which was published in the renowned scientific journal Immunity, investigated the communication between inflammation and liver metabolism during chronic viral infection.

26 Nov 2019

Tips for a gluten-free Thanksgiving dinner

Thanksgiving is a holiday built around a meal. And the meal is a specific one, with the menu largely set in stone.