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Metformin fails to improve insulin resistance in type 1 diabetes

Metformin treatment in type 1 diabetes lowers insulin dosage but does not improve insulin resistance, highlighting its complex role in diabetes management.

26 Nov 2025

Blocking immune cell signals reduces scar tissue formation in wounds

Researchers at the University of Arizona uncovered a previously unknown population of circulating immune cells that play a critical role in fibrosis, the buildup of scar tissue that can lead to organ failure and disfigurement.

25 Nov 2025

Obesity-related metabolic stress may affect brain health far earlier than expected

For decades, scientists have known that what harms the body often harms the brain. Conditions such as obesity, high blood pressure and insulin resistance strain the body's vascular and metabolic systems.

25 Nov 2025

Assessment of pre-procedure versus spray-as-you-go airway anesthesia protocols in bronchoscopy

Fiberoptic bronchoscopy involves various topical airway anesthesia protocols, which can impact patient comfort, procedural ease, and overall outcomes.

25 Nov 2025

Laparoscopic biliary atresia surgery in newborns reduces blood loss, improves jaundice recovery

Nagoya University researchers and their collaborators have found that minimally invasive laparoscopic surgery significantly reduces blood loss and improves jaundice recovery compared to traditional open surgery for treating biliary atresia-a serious liver condition in newborns.

25 Nov 2025

Polyamines restore gut regeneration in aging mice

With aging, the intestine gradually loses its ability to regenerate after damage. An international research team involving the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) in Jena and the University of Turin has now found that polyamines, small molecules produced naturally in the body, can play a decisive role in this process.

25 Nov 2025

New skin-permeable polymer delivers insulin without needles

Innovative zwitterionic polymer facilitates insulin absorption through the skin, offering a painless alternative to injections for diabetes management.

25 Nov 2025

Researchers uncover a new way to understand how children fare after liver transplantation

Researchers at the Icahn School of Medicine at Mount Sinai have uncovered a new way to understand how children fare after liver transplantation: by focusing not on medical test results, but on how differently parents and children perceive the child's well-being.

24 Nov 2025

Right-handed helical motion of malaria parasites revealed

With victims numbering in the millions, malaria is an infectious disease caused by the bite of a mosquito carrying the malaria parasite.

24 Nov 2025

Dexamethasone shows potential to fight therapy-resistant breast cancer metastases

The drug dexamethasone supplements cancer treatments to alleviate side effects of chemotherapy such as nausea or inflammation.

24 Nov 2025

Study finds GLP-1 drugs improve strength and reverse aging biology in mice

Researchers showed that GLP-1 receptor agonism counteracts aging across multiple organs in mice, improving strength and reversing molecular aging signatures without meaningful effects on body weight. These benefits depended largely on hypothalamic GLP-1R signaling and closely mirrored the anti-aging patterns produced by rapamycin.

23 Nov 2025

New signaling molecule drives development of tissue resident memory T cells

We owe a lot to tissue resident memory T cells (TRM). These specialized immune cells are among the body's first responders to disease.

22 Nov 2025

Combined healthy eating and exercise linked to greater reductions in visceral fat

Improving diet and increasing physical activity levels together may be more effective at preventing weight gain – particularly harmful fat inside the abdomen – than just changing one of these behaviours, new research from the University of Cambridge suggests.

21 Nov 2025

Reduced ketone body metabolism may be key to impaired energy production in type 2 diabetes

The liver plays a central role in storing and supplying energy to the body. In type 2 diabetes and metabolic dysfunction-associated steatotic liver disease (MASLD, commonly referred to as fatty liver disease), mitochondria-the cell's power plants-cannot switch efficiently between fuel sources.

21 Nov 2025

Marine bacterium shows powerful therapeutic effects against colorectal cancer

A research team led by Professor Eijiro Miyako at the Graduate School of Advanced Science and Technology, Japan Advanced Institute of Science and Technology (JAIST), has discovered that the marine bacterium Photobacterium angustum demonstrates remarkable therapeutic efficacy against colorectal cancer.

21 Nov 2025

Breakthrough medium transforms canine stem cells into beating cardiomyocytes

In research, induced pluripotent stem (iPS) cells are derived from skin, urine, or blood samples and developed into other cells, like heart tissue, that researchers want to study.

21 Nov 2025

US cancer registries, constrained by Trump policies, to recognize only ‘male’ or ‘female’ patients

The top authorities of U.S. cancer statistics will soon have to classify the sex of patients strictly as male, female, or unknown, a change scientists and advocates say will harm the health of transgender people, one of the nation's most marginalized populations.

21 Nov 2025

Liver News and Research

Metformin fails to improve insulin resistance in type 1 diabetes

Blocking immune cell signals reduces scar tissue formation in wounds

Obesity-related metabolic stress may affect brain health far earlier than expected

Assessment of pre-procedure versus spray-as-you-go airway anesthesia protocols in bronchoscopy

Laparoscopic biliary atresia surgery in newborns reduces blood loss, improves jaundice recovery

Polyamines restore gut regeneration in aging mice

New skin-permeable polymer delivers insulin without needles

Researchers uncover a new way to understand how children fare after liver transplantation

Right-handed helical motion of malaria parasites revealed

Dexamethasone shows potential to fight therapy-resistant breast cancer metastases

Study finds GLP-1 drugs improve strength and reverse aging biology in mice

New signaling molecule drives development of tissue resident memory T cells

Combined healthy eating and exercise linked to greater reductions in visceral fat

Reduced ketone body metabolism may be key to impaired energy production in type 2 diabetes

Marine bacterium shows powerful therapeutic effects against colorectal cancer

Breakthrough medium transforms canine stem cells into beating cardiomyocytes

US cancer registries, constrained by Trump policies, to recognize only ‘male’ or ‘female’ patients

Cancer stole her voice. She used AI, curse words, and kids’ books to get it back.

After series of denials, his insurer approved doctor-recommended cancer care. It was too late.

AGA issues updated guidance for pharmacologic treatment of moderate-to-severe Crohn's disease

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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