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Saturated fats accelerate neurodegeneration in multiple sclerosis

Targeting ceramide synthase enzymes may reduce multiple sclerosis severity by limiting ceramide C16 synthesis, offering potential neuroprotective strategies.

6 Nov 2024

New research explores how omega-3 and omega-6 fatty acids may impact cancer rates

This study highlights the relationship between polyunsaturated fatty acids and cancer risk, suggesting blood biomarkers may be key for accurate assessment.

6 Nov 2024

Werner syndrome gene plays key role in maintaining cellular organization and DNA stability

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 20 on October 17, 2024, entitled, "Werner syndrome RECQ helicase participates in and directs maintenance of the protein complexes of constitutive heterochromatin in proliferating human cells."

5 Nov 2024

Carbonic anhydrase inhibitors clear tau build-up in zebrafish models of tauopathies

A drug commonly used to treat glaucoma has been shown in zebrafish and mice to protect against the build-up in the brain of the protein tau, which causes various forms of dementia and is implicated in Alzheimer’s disease.

4 Nov 2024

Researchers achieve accurate EV analysis to detect brain disease

Brain disorders like Parkinson's (PD) or Alzheimer's Disease (AD) start to develop in patients much earlier than when their first clinical symptoms appear. Treating patients at these early stages could slow or even stop their disease, but there is currently no way to diagnose brain disorders at those pre-symptomatic stages.

3 Nov 2024

Glaucoma medication may help prevent Alzheimer's-related tau build-up

1 Nov 2024

Transcranial ultrasound stimulation: A new frontier in noninvasive brain therapy

Transcranial ultrasound stimulation combines accuracy and reversibility, paving the way for innovative treatments of neurological and psychiatric disorders.

1 Nov 2024

Brain actively engages with immune system to maintain health

The brain constantly engages in dialogue with the body's immune system. Such communication appears aimed at ensuring a delicate balance between defending against injury and infection and guarding healthy tissue.

1 Nov 2024

Understanding protein transport mechanisms could enhance crop yields

Botanists have come to understand the channels and transporters involved in the uptake and transport of nutrients, yet how are they positioned where they need to be?

30 Oct 2024

Innovative method promises quick cancer diagnosis using ultrathin membranes

There are billions of tiny packets of cellular material called extracellular vesicles (EVs) that are produced by cells and released into each person's blood, saliva, and other bodily fluids.

29 Oct 2024

Study provides new insights into the molecular causes of rare, fatal hereditary disease

A study entitled "IER3IP1-mutations cause microcephaly by selective inhibition of ER-Golgi transport", now published in the open access journal "Cellular and Molecular Life Sciences", provides new insights into the molecular causes of a rare and usually fatal hereditary disease called MEDS1.

28 Oct 2024

Clinical utility of carbonic anhydrase IX in diagnosing pleural mesothelioma

Mesothelioma is an aggressive tumor with a poor prognosis. Histological diagnosis of mesothelioma using limited tissue samples can be challenging.

27 Oct 2024

Bioactive peptides from Chlorella vulgaris for therapeutic applications

Chlorella vulgaris is a green, photosynthetic microalga in the phylum Chlorophyta. The goal of our study was to perform a bioinformatics analysis of Photosystem I P700 chlorophyll a apoprotein A2, one of its photosynthesis-related proteins, and to hunt for potent bioactive peptides.

27 Oct 2024

Novel findings on GRB2 and SOS1 could pave the way for cancer treatments

Researchers from Tokyo Metropolitan University have uncovered new insights into how the proteins GRB2 and SOS1 in cells pass signals from membrane receptors to nuclei.

26 Oct 2024

Study reveals resistance of Pseudomonas aeruginosa to common cleaning agents

A new study reveals widespread resistance of a major bacterial pathogen to the active ingredients in cleaning agents commonly used in hospitals and homes.

25 Oct 2024

Researchers unlock potential of light-controlled cellular activities

Researchers at the Paul Scherrer Institute PSI have succeeded in elucidating the structure of specific photoreceptors.

25 Oct 2024

Antibiotic for liver disease linked to emergence of antimicrobial resistant superbug

An international team of researchers has found that an antibiotic commonly prescribed for patients with liver disease, called rifaximin, has led to the global emergence of an almost untreatable form of the antimicrobial resistant superbug vancomycin-resistant enterococcus faecium (VRE), which frequently causes serious infections in hospitalized patients.

24 Oct 2024

Structural biology reveals secrets of DEV phage infection

The viruses that infect bacteria are the most abundant biological entities on the planet. For example, a recent simple study of 92 showerheads and 36 toothbrushes from American bathrooms found more than 600 types of bacterial viruses, commonly called bacteriophages or phages.

22 Oct 2024

Discovery of new bacterial toxins opens path to novel infection treatments

Researchers have discovered a new group of bacterial toxins that can kill harmful bacteria and fungi, opening the door to potential new treatments for infections.

22 Oct 2024

Beer consumption alters red blood cell lipid composition

Moderate intake of both alcoholic and non-alcoholic beer causes mild changes in red blood cell membrane lipid composition without impacting membrane fluidity.

21 Oct 2024