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Novel oncolytic virus expressing BiTE molecule elicits T cell-mediated killing of tumor cells

In a research article published in EMBO Molecular Medicine, a group of scientists at the University of Oxford have described a new twist on cancer immunotherapy, combining two independent cell killing approaches in a single therapeutic with high potency and broad applicability.

13 Mar 2018

Study identifies two new biomarkers for common form of childhood cancer

Two new biomarkers for a type of cancer in children called neuroblastoma have been identified in a study published in the journal Cancer Cell. The findings are expected to have immediate significance for disease prognosis, and eventually also for treatment.

13 Mar 2018

TSRI researchers show path to developing treatments for Charcot-Marie-Tooth disease

Scientists at The Scripps Research Institute have now shown a path to developing treatments for disease subtype CMT2D.

8 Mar 2018

Researchers determine cause of difficult-to-control mitochondrial diseases

A Japanese research group has discovered that taurine is conjugated with mitochondrial transfer RNAs (tRNAs), small RNAs that decode genetic information, and that taurine deficiency in tRNA dramatically reduces both mitochondrial protein translation and impairs mitochondrial membrane integrity.

7 Mar 2018

Researchers reveal new molecular target to help ease asthma symptoms

Researchers at UC Davis Health and Albany Medical College have shown that the protein vascular endothelial growth factor A -- or VEGFA -- plays a major role in the inflammation and airway obstruction associated with asthma.

7 Mar 2018

New class of antimicrobial polymers can kill five hard-to-treat multidrug-resistant bacteria

An international research team led by the Institute of Bioengineering and Nanotechnology of the Agency for Science, Technology and Research and IBM Research developed a synthetic molecule that can kill five deadly types of multidrug-resistant bacteria with limited, if any, side effects.

7 Mar 2018

New suggests different approach to eczema treatment

Eczema affects about 17 percent of children in developed countries and is often the gateway to food allergy and asthma, initiating an "atopic march" toward broader allergic sensitization.

6 Mar 2018

Research identifies new biomarkers for future dementia risk

Sudha Seshadri, M.D., founding director of the Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases at UT Health San Antonio, is co-leader and senior author on research announced March 6 that identifies novel biomarkers of risk for future dementia.

6 Mar 2018

Research shows how interaction between nervous and immune systems occurs in lung infections

When the body is fighting infection, the immune system kicks into high gear. But emerging evidence hints at the involvement of another, rather surprising, player in this process: the nervous system.

5 Mar 2018

Researchers find way to effectively stop internal bleeding using magnetically-driven nanoparticles

Scientists from ITMO University have found a way to effectively stop internal bleeding by magnetically-driven nanoparticles containing thrombin.

5 Mar 2018

New compounds targeting epigenetics show promise in lymphoma patients

New compounds targeting epigenetics have shown remarkable early activity in patients with lymphoma, according to data presented at the TAT (Targeted Anticancer Therapies) International Congress 2018 in Paris, France.

5 Mar 2018

Researchers develop method to identify splicing-based biomarkers for liver cancer

Because liver cancer is particularly diverse, genetically, and prone to relapse, identifying biomarkers that can predict disease progression is a critical goal in the fight against it.

2 Mar 2018

Johns Hopkins researchers invent new class of immunotherapy drugs to fight cancer

Johns Hopkins researchers have invented a new class of cancer immunotherapy drugs that are more effective at harnessing the power of the immune system to fight cancer.

2 Mar 2018

Skin bacteria may be an answer to cancer find researchers

The skin protects the body from harm and is also covered with billions of bacteria which are called commensal bacteria that form the microbiota of the skin. These are friendly bacteria that stay on the skin surface without causing harm.

2 Mar 2018

Researchers report potential new role for skin bacteria in protecting against cancer

Science continues to peel away layers of the skin microbiome to reveal its protective properties. In a study published in Science Advances on February 28, University of California San Diego School of Medicine researchers report a potential new role for some bacteria on the skin: protecting against cancer.

1 Mar 2018

Researchers discover novel mechanism that leads to pleural effusion in lung cancer patients

Lung cancer patients are particularly susceptible to malignant pleural effusion, when fluid collects in the space between the lungs and the chest wall.

1 Mar 2018

RNA-based method cures lung tumors in mice

By turning down the activity of a specific RNA molecule researchers at Sahlgrenska Academy, Sweden, have cured lung tumors in mice by 40-50 percent.

28 Feb 2018

Receptors crucial for establishing strong memories

When we create a memory, a pattern of connections forms between neurons in the brain. New work from UC Davis shows how these connections can be strengthened or weakened at a molecular level. The study is published Feb. 27 in the journal Cell Reports.

27 Feb 2018

Quiescent cells also acquire particular type of mutation, research shows

For almost a hundred years, geneticists have believed that the more a cell divides the more mutations it acquires. However, research by scientists at the Institut Pasteur shows that quiescent cells, which do not divide, also acquire a particular type of mutation - deletions (mutations through loss of nucleobases).

27 Feb 2018

Fresh insights into depression could pave way for new therapies

Fresh insights into changes in the brain linked to depression could pave the way for new therapies.

27 Feb 2018

Molecule News and Research

Novel oncolytic virus expressing BiTE molecule elicits T cell-mediated killing of tumor cells

Study identifies two new biomarkers for common form of childhood cancer

TSRI researchers show path to developing treatments for Charcot-Marie-Tooth disease

Researchers determine cause of difficult-to-control mitochondrial diseases

Researchers reveal new molecular target to help ease asthma symptoms

New class of antimicrobial polymers can kill five hard-to-treat multidrug-resistant bacteria

New suggests different approach to eczema treatment

Research identifies new biomarkers for future dementia risk

Research shows how interaction between nervous and immune systems occurs in lung infections

Researchers find way to effectively stop internal bleeding using magnetically-driven nanoparticles

New compounds targeting epigenetics show promise in lymphoma patients

Researchers develop method to identify splicing-based biomarkers for liver cancer

Johns Hopkins researchers invent new class of immunotherapy drugs to fight cancer

Skin bacteria may be an answer to cancer find researchers

Researchers report potential new role for skin bacteria in protecting against cancer

Researchers discover novel mechanism that leads to pleural effusion in lung cancer patients

RNA-based method cures lung tumors in mice

Receptors crucial for establishing strong memories

Quiescent cells also acquire particular type of mutation, research shows

Fresh insights into depression could pave way for new therapies

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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