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Resverlogix commences RVX-208 Phase 2 trial in pre-diabetes mellitus

Resverlogix Corp. today announced that it has initiated an exploratory Phase 2 clinical trial in patients with pre-diabetes mellitus to examine the effects of RVX-208 and ApoA-I production on glucose metabolism.

17 Oct 2012

LRRK2 inhibitors may provide neuroprotection for patients with Parkinson's

For decades, patients with Parkinson's disease (PD) have had the same experience. Their hands start to shake uncontrollably, their limbs become rigid and they lose their balance. Years before those movement problems set in, many begin struggling with fainting, incontinence, sexual dysfunction, anxiety and depression. Many patients are still treated with a 42-year-old drug called L-DOPA, which temporarily staves off symptoms but can itself cause heart arrhythmias, stomach bleeding and hallucinations.

16 Oct 2012

Companionship can reduce nerve-related pain

Companionship has the potential to reduce pain linked to nerve damage, according to a new study.

16 Oct 2012

First report of androgen-dependence of exercise on nerve regeneration

A study by researchers from Emory University and Indiana University found that the beneficial effects daily exercise can have on the regeneration of nerves also require androgens such as testosterone in both males and females. It is the first report of both androgen-dependence of exercise on nerve regeneration and of an androgenic effect of exercise in females.

16 Oct 2012

Study demonstrates how new scientific knowledge drives novel treatments for spinal cord injuries

Research released today demonstrates how new scientific knowledge is driving innovative treatments for spinal cord injuries. Spinal cord damage is debilitating and life-altering, limiting or preventing movement and feeling for millions worldwide, and leading to chronic health conditions and pain.

16 Oct 2012

Embryonic neuron transplants could effectively treat brain diseases

The unexpected survival of embryonic neurons transplanted into the brains of newborn mice in a series of experiments at the University of California, San Francisco (UCSF) raises hope for the possibility of using neuronal transplantation to treat diseases like Alzheimer's, epilepsy, Huntington's, Parkinson's and schizophrenia.

15 Oct 2012

New insights into how brain responds to extreme stress

Researchers report new insights into how the brain responds to extreme stress, whether from combat, natural disasters, or repeated violent competition. The insights offer hope for detecting and treating several widespread and debilitating neuropsychiatric disorders, and were presented at Neuroscience 2012, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news about brain science and health.

15 Oct 2012

Hip arthroscopy traction weight key to nerve outcome

Minimizing traction weight during hip arthroscopy in the lateral position may protect against sciatic nerve injury, report US surgeons.

12 Oct 2012

Researchers discover how indoor mould makes people sick

For more than a decade, it has been known that the fungus Trichoderma longibrachiatum is the most common finding wherever people are suffering from health hazards related to damp building damage. However, it has not been known how this mould - which is typical of most buildings with indoor air problems - harms people's health. Published in September, a study by a team of researchers at the Department of Food and Environmental Sciences of the University of Helsinki explains how microbial metabolites in the living environment cause health problems

12 Oct 2012

Menstrual cycle alters muscle activation patterns in female athletes

Numerous studies have shown that female athletes are more likely to get knee injuries, especially anterior cruciate ligament (ACL) tears and chronic pain, than their male counterparts.

12 Oct 2012

Brain scans can identify reading skills of children

If a 7-year-old is breezing through the "Harry Potter" books, studies indicate that he or she will be a strong reader later in life. Conversely, if a 7-year-old is struggling with "The Cat in the Hat," that child will most likely struggle with reading going forward.

12 Oct 2012

Tourniquet timing alters foot surgery pain outcomes

The timing of thigh tourniquet application may affect pain control in patients undergoing forefoot surgery, research published in Foot and Ankle Surgery suggests.

11 Oct 2012

Transplanted neural stem cells able to produce new myelin in children with PMD

A Phase I clinical trial led by investigators from the University of California, San Francisco and sponsored by Stem Cells Inc., showed that neural stem cells successfully engrafted into the brains of patients and appear to have produced myelin.

11 Oct 2012

New drug candidate improves cognitive function of rats with Alzheimer's-like mental impairment

Washington State University researchers have developed a new drug candidate that dramatically improves the cognitive function of rats with Alzheimer's-like mental impairment.

11 Oct 2012

Zero out of TEN for fecal incontinence treatment

Transcutaneous electrical nerve stimulation is no more effective than placebo for the treatment of fecal incontinence, say French researchers.

10 Oct 2012

Non-surgical orthopedic medical devices: an interview with Brian Moore, Director of Sales and Product Marketing from DJO global

Non-surgical orthopedic medical devices are products designed to help relieve pain in specific parts of the body.

10 Oct 2012

People with diabetic foot ulcers more likely to die prematurely

People with diabetes who develop foot ulcers are at more risk of dying prematurely than those without the complication, finds a new large-scale study. The researchers say the findings highlight the potential need for improved detection and management of those with diabetes and foot ulcers.

10 Oct 2012

Anesthetic-loaded liposomes can delay onset of neuropathic pain

Using tiny spheres filled with an anesthetic derived from a shellfish toxin, researchers at Boston Children's Hospital and the Massachusetts Institute of Technology have developed a way to delay the rise of neuropathic pain, a chronic form of pain that arises from flawed signals transmitted by damaged nerves.

10 Oct 2012

Mayo researchers discover new therapy for patients with neuromyelitis optica

Mayo Clinic researchers have identified a new therapy for patients with neuromyelitis optica that appears to stop inflammation of the eye nerves and spinal cord. NMO is a debilitating central nervous system disorder that is often misdiagnosed as multiple sclerosis (MS).

10 Oct 2012