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Toward patient-derived models to help personalize cancer care

Cancer is a major, worldwide challenge, and its impact is projected to escalate due to aging and growth of the population.

21 Jan 2021

A single genetic test can identify the presence and cause of mismatch repair deficiency

Researchers have developed a new integrated genetic/epigenetic DNA-sequencing protocol known as MultiMMR that can identify the presence and cause of mismatch repair (MMR) deficiency in a single test from a small sample of DNA in colon, endometrial, and other cancers.

21 Jan 2021

Nicotine promotes breast cancer lung metastasis, finds study

Breast cancer is the second most common cancer among women in the United States, and cigarette smoking is associated with a higher incidence of breast cancer spread, or metastasis, lowering the survival rate by 33% at diagnosis.

21 Jan 2021

Researchers immunoengineer nanobead system for circulating tumor cell detection

A team of researchers has immunoengineered a nanobead system for the isolation and detection of circulating tumor cells.

21 Jan 2021

Cancer patients have higher risk of severe COVID -19 infection than non-cancer patients

Patients with inactive cancer and not currently undergoing treatments also face a significantly higher risk of severe illness from COVID-19, a new study from Penn Medicine published online today in JNCI Cancer Spectrum shows.

21 Jan 2021

Idiopathic intracranial hypertension is on the rise, finds study

A new study has found a brain pressure disorder called idiopathic intracranial hypertension is on the rise, and the increase corresponds with rising obesity rates.

20 Jan 2021

Potentially promising therapeutic combination for renal cell carcinoma uncovered

Renal cell carcinoma (RCC) is the most common form of cancer of the kidney. In 2018, there were an estimated 403,000 new cases of RCC and 175,000 deaths due to kidney cancer worldwide.

20 Jan 2021

Eliminating key gene could revive exhausted immune cells to battle solid tumors

Eliminating a single gene can turn exhausted cancer-fighting immune cells known as CD8+ T cells back into refreshed soldiers that can continue to battle malignant tumors, a new study led by UT Southwestern researchers suggests.

20 Jan 2021

Designer DNA agent reduces myeloma stem cell abundance, lowers disease burden in mice

Many patients with multiple myeloma, a type of blood cancer, eventually develop resistance to one treatment after another. That's in part because cancer stem cells drive the disease -- cells that continually self-renew. If a therapy can't completely destroy these malignant stem cells, the cancer is likely to keep coming back.

20 Jan 2021

Putatively immature dendritic cells may induce robust immune responses in young children

A study by Ludwig-Maximilians-Universitaet (LMU) in Munich researchers shows that putatively immature dendritic cells found in young children are able to induce robust immune responses. The results could lead to improved vaccination protocols.

20 Jan 2021

Researchers develop ultra-small nanomedicines to target intractable cancers

Ultra-small nanomedicines of approximately 18 nm were fabricated by dynamic ion-pairing between Y-shaped block copolymers and nucleic acid drugs, such as siRNA and antisense drugs.

19 Jan 2021

Researchers develop FLASH ultra-high-dose rate radiation therapy beam for cancer treatment

A joint team of researchers from Radiation Oncology at Dartmouth's and Dartmouth-Hitchcock's Norris Cotton Cancer Center, Dartmouth Engineering, and Dartmouth-Hitchcock's Department of Surgery have developed a method to convert a standard linear accelerator, used for delivery of radiation therapy cancer treatment, to a FLASH ultra-high-dose rate radiation therapy beam.

19 Jan 2021

$Researchers develop new method to regenerate bone and heal severe fractures$

Researchers develop new method to regenerate bone and heal severe fractures

Researchers at Lund University in Sweden, in collaboration with colleagues in Dresden, Germany, have developed a way of combining a bone substitute and drugs to regenerate bone and heal severe fractures in the thigh or shin bone.

19 Jan 2021

Researchers identify new drug combination that can treat acute myeloid leukemia

Scientists have identified two drugs that are potent against acute myeloid leukemia (AML) when combined, but only weakly effective when used alone.

19 Jan 2021

New method could provide additional insight into brain tumors

A look at RNA tells us what our genes are telling our cells to do, and scientists say looking directly at the RNA of brain tumor cells appears to provide objective, efficient evidence to better classify a tumor and the most effective treatments.

19 Jan 2021

Researchers define tumor invasion machinery orchestrated by a master cancer gene

Researchers investigated how cancer genes lead to the breakdown of the capsule that prevents cancerous cells from invading the surrounding healthy tissues and - find a hijacked "molecular crowbar".

18 Jan 2021

Novel organoid models illuminate path to cervical cancers

How do tumors develop in the cervix? Many new details are now known about this question. This is also thanks to Dr. Cindrilla Chumduri from the Biocentre at the University of Würzburg.

18 Jan 2021

Researchers figure out the precise mechanics involved in cell motility

Theoretical physicists from Berlin teamed up with experimental physicists from Munich to determine the precise mechanics involved in cell motility. The findings were published in the journal Proceedings of the National Academy of Sciences.

18 Jan 2021

New computational technique accurately differentiates between data from tumor cells and normal cells

In an effort to address a major challenge when analyzing large single-cell RNA-sequencing datasets, researchers from The University of Texas MD Anderson Cancer Center have developed a new computational technique to accurately differentiate between data from cancer cells and the variety of normal cells found within tumor samples.

18 Jan 2021

Study provides a mathematical description of how tumor metastasis starts

A scientific study carried out by the Universidad Carlos III de Madrid and the Universidad Complutense de Madrid (UCM) has produced a mathematical description of the way in which a tumor invades the epithelial cells and automatically quantifies the progression of the tumor and the remaining cell islands after its progression.

18 Jan 2021

Tumor News and Research

Toward patient-derived models to help personalize cancer care

A single genetic test can identify the presence and cause of mismatch repair deficiency

Nicotine promotes breast cancer lung metastasis, finds study

Researchers immunoengineer nanobead system for circulating tumor cell detection

Cancer patients have higher risk of severe COVID -19 infection than non-cancer patients

Idiopathic intracranial hypertension is on the rise, finds study

Potentially promising therapeutic combination for renal cell carcinoma uncovered

Eliminating key gene could revive exhausted immune cells to battle solid tumors

Designer DNA agent reduces myeloma stem cell abundance, lowers disease burden in mice

Putatively immature dendritic cells may induce robust immune responses in young children

Researchers develop ultra-small nanomedicines to target intractable cancers

Researchers develop FLASH ultra-high-dose rate radiation therapy beam for cancer treatment

Researchers develop new method to regenerate bone and heal severe fractures

Researchers identify new drug combination that can treat acute myeloid leukemia

New method could provide additional insight into brain tumors

Researchers define tumor invasion machinery orchestrated by a master cancer gene

Novel organoid models illuminate path to cervical cancers

Researchers figure out the precise mechanics involved in cell motility

New computational technique accurately differentiates between data from tumor cells and normal cells

Study provides a mathematical description of how tumor metastasis starts

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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