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Early overnutrition rewires developing brains to crave unhealthy food in adulthood

People whose mothers are overweight during pregnancy and nursing may become obese as adults because early overnutrition rewires developing brains to crave unhealthy food, according to a Rutgers study in Molecular Metabolism.

20 Mar 2023

AI-based design method synthesizes polymers that mimic blood plasma

Most life on Earth is based on polymers of 20 amino acids that have evolved into hundreds of thousands of different, highly specialized proteins. They catalyze reactions, form backbone and muscle and even generate movement.

20 Mar 2023

Leaving lymph nodes intact until after immunotherapy could boost efficacy against solid tumors

Cancer treatment routinely involves taking out lymph nodes near the tumor in case they contain metastatic cancer cells.

20 Mar 2023

Using unsupervised machine learning algorithms to classify osteosarcoma

A new editorial paper was published in Oncotarget's Volume 14 on February 11, 2023, entitled, "Unlocking the potential of molecular-driven stratification for osteosarcoma treatment and prognosis."

20 Mar 2023

Novel RNA sense-and-respond circuit harnesses the force of enzymes to develop better drugs

More than twelve billion doses of mRNA vaccines have been administered globally since the start of the COVID pandemic, saving millions of lives. But RNA-based therapies for other diseases have so far proven more challenging to develop.

20 Mar 2023

Upgraded tumor model points the way toward more effective cancer therapies

Tumor cells won't show their true selves in a petri dish, isolated from other cells.

20 Mar 2023

Poor inflammatory immune response in obese patients increases susceptibility to severe COVID-19

Individuals who are obese may be more susceptible to severe COVID-19 because of a poorer inflammatory immune response, say Cambridge scientists.

20 Mar 2023

COVID-19 patients more likely to develop gastrointestinal disorders

COVID-19 is associated with an increased risk of developing long-term gastrointestinal disorders, including irritable bowel syndrome.

20 Mar 2023

UK Government names two leaders to spearhead new Dementia Mission

The UK Government has named two leaders in dementia research to spearhead the ambitious national Mission to tackle dementia, which was launched in memory of the late Dame Barbara Windsor.

20 Mar 2023

Judge signals he could rule to halt sales of common abortion pill

During a four-hour hearing last week that could eliminate nationwide access to a common and widely used abortion pill, federal Judge Matthew Kacsmaryk, of the Northern District of Texas, signaled his conservative Christian beliefs early and often.

20 Mar 2023

Female rheumatoid arthritis patients taking sex hormones have greater chance of achieving remission

A large study of women with rheumatoid arthritis has found that those taking oral contraceptives or hormone replacement therapy (HRT) had a greater chance of achieving remission.

20 Mar 2023

Gut microbiomes and mental health: how do they interact?

A new study published in the journal Frontiers in Medicine reviewed recent literature on the link between gut microbiota, the brain, and neurological disorders.

19 Mar 2023

California picks generic drug company Civica to produce low-cost insulin

Gov. Gavin Newsom on Saturday announced the selection of Utah-based generic drug manufacturer Civica to produce low-cost insulin for California, an unprecedented move that makes good on his promise to put state government in direct competition with the brand-name drug companies that dominate the market.

19 Mar 2023

Usefulness of dried blood spot samples for monitoring HCV infection in people who inject drugs

A study with people who inject drugs evaluated a minimally invasive test based on dried blood spots (DBS) for the monitoring of hepatitis C virus (HCV) infection.

17 Mar 2023

Novel therapeutic eradicates gastric cancer in treated mice

A novel cancer therapeutic, combining antibody fragments with molecularly engineered nanoparticles, permanently eradicated gastric cancer in treated mice, a multi-institutional team of researchers found.

17 Mar 2023

Scientists develop a marker for therapy response in acute myeloid leukemia

With the combination of the drugs Venetoclax and 5-Azacitidine, a new, effective and more tolerable alternative to chemotherapy for the treatment of AML has been available for several years. But for some patients, the drug combination does not work.

17 Mar 2023

Study demonstrates effectiveness of a procedure done under the skin to treat uncontrolled hypertension

Hypertension remains poorly controlled worldwide and is becoming more common. Lifestyle changes and blood pressure-reducing drugs are the mainstays of therapy for hypertension, but despite widespread availability of these approaches, many patients with hypertension are not adequately treated.

17 Mar 2023

Drugs News and Research

Early overnutrition rewires developing brains to crave unhealthy food in adulthood

AI-based design method synthesizes polymers that mimic blood plasma

Leaving lymph nodes intact until after immunotherapy could boost efficacy against solid tumors

Using unsupervised machine learning algorithms to classify osteosarcoma

Novel RNA sense-and-respond circuit harnesses the force of enzymes to develop better drugs

Upgraded tumor model points the way toward more effective cancer therapies

Poor inflammatory immune response in obese patients increases susceptibility to severe COVID-19

COVID-19 patients more likely to develop gastrointestinal disorders

UK Government names two leaders to spearhead new Dementia Mission

Judge signals he could rule to halt sales of common abortion pill

Female rheumatoid arthritis patients taking sex hormones have greater chance of achieving remission

Gut microbiomes and mental health: how do they interact?

California picks generic drug company Civica to produce low-cost insulin

Usefulness of dried blood spot samples for monitoring HCV infection in people who inject drugs

Novel therapeutic eradicates gastric cancer in treated mice

Scientists develop a marker for therapy response in acute myeloid leukemia

Study demonstrates effectiveness of a procedure done under the skin to treat uncontrolled hypertension

Designer DNA drug could be used to delay paralysis in ALS

Study reveals the underlying mechanism by which TKI cancer drugs cause inflammation

Drug combination may reduce the risk of prostate cancer progression, death

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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