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Biotech company defends patent on gene mutation for breast cancer

A US biotechnology company is defending the granting of a controversial patent over a common genetic mutation for breast cancer, rejecting accusations it amounts to the privatization of the human body.

21 Feb 2012

FDA grants Priority Review for Repligen's SecreFlo NDA

Repligen Corporation announced today that the U.S. Food and Drug Administration (FDA) has accepted for filing and granted Priority Review to the Company's new drug application (NDA) for SecreFlo for the improved detection of pancreatic duct abnormalities in patients with pancreatitis.

21 Feb 2012

Medco fourth-quarter total net revenues increase 12.2% to record $19.0 billion

Medco Health Solutions, Inc. today reported record fourth-quarter 2011 GAAP diluted EPS of $1.08, an increase of 22.7 percent, which includes expenses associated with the pending merger with Express Scripts, Inc. of $43.6 million before provision for income taxes. When excluding these merger-related expenses, diluted EPS increased 29.5 percent over fourth-quarter 2010.

21 Feb 2012

Innovative testing technology helps hospital save $3.7M

Kettering Medical Center has realized a positive financial impact of $3.7 million in the past year as the result of a change in standard operating procedures using a new innovative testing technology that diagnoses a wide variety of infectious diseases faster and more accurately than traditional testing.

20 Feb 2012

KI's chemical interaction map shows how inhibitors bind to PARP enzymes

A team of researchers at Karolinska Institutet in Sweden has generated a map over the effects of small drug-like molecules on PARP1 and other similar proteins in the body. This map may explain the mechanism behind putative side effects of the so-called PARP inhibitors, and can play an important role in the development of novel tailor-made cancer drugs.

20 Feb 2012

DNA ‘nanorobot’ effectively targets cancer leaving healthy cells untouched: Study

Researchers have developed ‘nano-sized’ probes built from DNA that can seek and destroy cancer cells, leaving healthy cells untouched. These ‘nanorobots’ release their drug payload only when they reach and identify their target and are believed to improve many treatments for disease.

20 Feb 2012

Remote controlled microchip successfully delivers drug in early clinical trial

Researchers have developed a new microchip implant device that can deliver bone-building drugs to seven osteoporosis patients. The microchips worked inside patients as drug-delivering pacemakers, following a prescription plan sent by radio signal.

18 Feb 2012

Aptuit sells Clinical Trials Supply business to Catalent Pharma Solutions

Aptuit announces the completion of the sale of the Clinical Trials Supply business to Catalent Pharma Solutions on February 17, 2012. Timothy C. Tyson, Chairman and CEO of Aptuit, LLC stated that Aptuit will continue to deliver scientific and service excellence to provide integrated capabilities for the early to mid phase drug development markets.

18 Feb 2012

Study examines mercury exposure in pregnant women

A new study published by researchers at SUNY Downstate Medical Center's School of Public Health assesses mercury levels in pregnant women and examines dietary and environmental sources of exposure to mercury. The research, which focuses on an urban immigrant community, examined risk factors that may be associated with elevated mercury levels, measured through urine and cord blood samples.

18 Feb 2012

Nano-enabled intranasal formulation of teriparatide can treat osteoporosis

The University of Nottingham spin-out company, Critical Pharmaceuticals, has announced a -545,000 collaboration with the University to develop a nano-enabled intranasal formulation of teriparatide for the treatment of osteoporosis.

18 Feb 2012

MDC publishes latest research report on cardiovascular and metabolic diseases

The Max Delbr-ck Center for Molecular Medicine (MDC) Berlin-Buch, which celebrates its 20th anniversary this year, has published its latest research report. In the 298-page book that is primarily written in English, all of the 67 research groups of the MDC and the clinical groups in the Experimental and Clinical Research Center (ECRC) of the MDC and of the Charit- - Universit-tsmedizin Berlin give an overview of their work in 2010 - 2011.

18 Feb 2012

Digital games become an important tool for self-management of illness and chronic conditions

Millions of dollars and immeasurable hours of research and development are being invested to develop and employ increasingly sophisticated hardware and software technologies to deliver innovative new personalized health care interventions.

17 Feb 2012

Nordion celebrates first anniversary of market launch of TheraSphere

Nordion Inc., a leading provider of products and services to the global health science market, today celebrated the first anniversary of the market introduction of TheraSphere, an innovative radioembolic liver cancer therapy, in the Republic of Turkey.

17 Feb 2012

Scientists create first 3-D living tissue model of glioma

Brown University scientists have created the first three-dimensional living tissue model, complete with surrounding blood vessels, to analyze the effectiveness of therapeutics to combat brain tumors. The 3-D model gives medical researchers more and better information than Petri dish tissue cultures.

17 Feb 2012

Synthetic Oct4 protein more effective at turning genes into pluripotent stem cells

Scientists have found a way to generate and maintain stem cells much more efficiently by amplifying the effect of an essential protein.

17 Feb 2012

Biochemists determine first crystal structure of an immunoproteasome

Like a shredder, the immunoproteasome cuts down proteins into peptides that are subsequently presented on the cellular surface. The immune system can distinguish between self and nonself peptides and selectively kills cells that due to a viral infection present non-self peptides at their surface. In autoimmune diseases this mechanism is deregulated and the immune system also eliminates uninfected cells by mistake.

16 Feb 2012