Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Silicon dioxide coated rust nanoparticles to fight cervical cancer

The next big thing in medical diagnostics could be minutes particles of rust, iron oxide, coated with the material from which sand is formed, silicon dioxide. These magnetic nanoparticles, a mere 29 to 230 nanometers across, can be used to trap antibodies to the virus that causes cervical cancer and to the bacteria that causes potentially lethal diarrhea.

1 Feb 2011

Scientists create 'reporter mouse' to close gap between kidney injury and diagnosis

The current check for kidney disease is a simple blood test for serum creatinine, but it can take longer than two days for this metabolite to accumulate to levels that are significant enough to indicate kidney damage - and by then it may be too late to intervene.

1 Feb 2011

GATTEX Phase 3 pivotal study reaches primary efficacy endpoint of reducing PN in patients with SBS

NPS Pharmaceuticals, a specialty pharmaceutical company developing innovative therapeutics for rare gastrointestinal and endocrine disorders, today announced that its Phase 3 pivotal study of GATTEX met the primary efficacy endpoint of reducing parenteral nutrition dependence in patients with adult short bowel syndrome.

31 Jan 2011

LFA launches new nationwide education series for people with lupus

The Lupus Foundation of America has launched a new nationwide education series, Lupus: Learn from the Experts, designed to provide people with lupus essential information about living with lupus from some of the world's leading lupus experts. The program is a series of teleconferences hosted by a lupus expert, and will cover a wide variety of topics important to people with lupus, including disability, kidney involvement, and clinical trials.

29 Jan 2011

New research shows CEUS can improve diagnosis of variety of medical conditions in children

New research released here Thursday shows that "contrast-enhanced ultrasound" can safely improve the diagnosis of a variety of medical conditions in children - without exposing them to ionizing radiation.

29 Jan 2011

USPTO issues Notice of Allowances to Lakewood's three patent applications for treatment of HUS

Lakewood-Amedex, a leading developer of novel anti-infective pharmaceuticals, announced today that the United States Patent and Trademark Office has issued Notice of Allowances on three patent applications relating to the use of novel monoclonal antibodies for the treatment of hemolytic uremic syndrome caused by shiga toxin II secreting E.coli O157: H7 strain.

28 Jan 2011

Magnetic nanoparticles for ovarian cancer treatment

A paper published in the January issue of the journal Nanomedicine could provide the foundation for a new ovarian cancer treatment option - one that would use an outside-the-body filtration device to remove a large portion of the free-floating cancer cells that often create secondary tumors.

28 Jan 2011

Racial disparities exist between kidney disease patients and physicians: Study

Significant disparities exist between the race of kidney disease patients and that of the physicians who will care for them, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology.

28 Jan 2011

Researchers discover new sensory neurons that mediate BP and metabolism regulation in liver

For 60 years, scientists have puzzled over the possibility of a hepatic osmoreceptor that influences blood pressure regulation. Now, researchers of the Max Delbr-ck Center for Molecular Medicine Berlin-Buch, the Experimental and Clinical Research Center of the MDC and Charit- and the Hannover Medical School appear to have made a breakthrough discovery.

27 Jan 2011

Abbott fourth quarter worldwide sales increase 13.4% to nearly $10 billion

Abbott today announced financial results for the fourth quarter ended Dec. 31, 2010.

27 Jan 2011

ChemoCentryx commences CCX832 Phase I trial in patients with psoriasis

ChemoCentryx, today announced the initiation of a Phase I clinical trial of CCX832, an orally-administered small molecule that is a potent and selective inhibitor of the chemoattractant receptor, ChemR23.

26 Jan 2011

Taiwanese research team develops large-scale proactive cancer treatment system first-generation prototype

A Taiwanese research team, led by Prof. Ming-Shing Young of Department of Electrical Engineering at National Cheng Kung University (NCKU), has successfully developed a large-scale proactive cancer treatment system first-generation prototype which includes Frequency-Adjustable High Frequency Induction Heating Machine (HFIHM) and 3D Magnetically Guiding Endoscope System (3DMGES).

25 Jan 2011

Raptor completes enrollment in DR Cysteamine Phase 3 clinical trial in cystinosis

Raptor Pharmaceutical Corp., today announced it has completed enrollment in its Phase 3 clinical trial of its proprietary delayed-release oral formulation of cysteamine bitartrate ("DR Cysteamine") in patients with nephropathic cystinosis ("cystinosis").

24 Jan 2011

Bayer's gadobutrol injection for CNS imaging receives FDA Advisory Committee approval

Bayer HealthCare Pharmaceuticals Inc. announced today that the Peripheral and Central Nervous System Drugs Advisory Committee to the U.S. Food and Drug Administration voted unanimously that clinical trial and postmarketing data for gadobutrol injection, a macrocyclic 1.0 molar gadolinium-based contrast agent (GBCA), support approval of the product for proposed use in diagnostic magnetic resonance imaging (MRI) in adults and children.

24 Jan 2011

Functional tests are necessary to understand human disease despite genetic sequencing

Despite what you might have heard, genetic sequencing alone is not enough to understand human disease. Researchers at Duke University Medical Center have shown that functional tests are absolutely necessary to understand the biological relevance of the results of sequencing studies as they relate to disease, using a suite of diseases known as the ciliopathies which can cause patients to have many different traits.

24 Jan 2011

What protects certain diabetics from complications?

Much research has been carried out on why diabetics develop complications. Now researchers are asking the question the other way around. They want to know why some diabetic patients do not develop complications. What is it that protects them? The PROLONG study could provide the answer.

21 Jan 2011

RBM, SMA Foundation collaborate to develop plasma protein biomarkers for spinal muscular atrophy

The Spinal Muscular Atrophy Foundation and Rules-Based Medicine, announced today that they have reached the first milestone in a program to develop a panel of plasma protein biomarkers for SMA using RBM's Multi-Analyte Profiling technology platform.

21 Jan 2011

Vasopressin in the brain maintains size of vasopressin neurons even when body fluid becomes more diluted

The anti-diuretic hormone "vasopressin" is released from the brain, and known to work in the kidney, suppressing the diuresis.

21 Jan 2011

MGH Bipolar CHOICE trial to evaluate effectiveness of new medications compared to lithium

The Massachusetts General Hospital (MGH) Bipolar Clinic and Research Program with the Bipolar Trials Network is launching Bipolar CHOICE, a 10-site nationwide trial evaluating the real-world advantages and disadvantages of quetiapine, a widely prescribed second generation antipsychotic mood stabilizing medication, compared to lithium, the gold standard mood stabilizer, for the treatment of outpatients with bipolar disorder.

21 Jan 2011

INF2 gene mutation is a major cause for focal segmental glomerulosclerosis

Mutations in a gene called INF2 are by far the most common cause of a dominantly inherited condition that leads to kidney failure, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology. The results may help with screening, prevention, and therapy.

21 Jan 2011

Nephrology News and Research

Further Reading

Silicon dioxide coated rust nanoparticles to fight cervical cancer

Scientists create 'reporter mouse' to close gap between kidney injury and diagnosis

GATTEX Phase 3 pivotal study reaches primary efficacy endpoint of reducing PN in patients with SBS

LFA launches new nationwide education series for people with lupus

New research shows CEUS can improve diagnosis of variety of medical conditions in children

USPTO issues Notice of Allowances to Lakewood's three patent applications for treatment of HUS

Magnetic nanoparticles for ovarian cancer treatment

Racial disparities exist between kidney disease patients and physicians: Study

Researchers discover new sensory neurons that mediate BP and metabolism regulation in liver

Abbott fourth quarter worldwide sales increase 13.4% to nearly $10 billion

ChemoCentryx commences CCX832 Phase I trial in patients with psoriasis

Taiwanese research team develops large-scale proactive cancer treatment system first-generation prototype

Raptor completes enrollment in DR Cysteamine Phase 3 clinical trial in cystinosis

Bayer's gadobutrol injection for CNS imaging receives FDA Advisory Committee approval

Functional tests are necessary to understand human disease despite genetic sequencing

What protects certain diabetics from complications?

RBM, SMA Foundation collaborate to develop plasma protein biomarkers for spinal muscular atrophy

Vasopressin in the brain maintains size of vasopressin neurons even when body fluid becomes more diluted

MGH Bipolar CHOICE trial to evaluate effectiveness of new medications compared to lithium

INF2 gene mutation is a major cause for focal segmental glomerulosclerosis

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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