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mRNA vaccine-induced antibodies shown to be more effective in neutralizing SARS-CoV-2 and its variants than natural immunity

Researchers designed an electrochemiluminescence-based serology test with remarkable sensitivity to precisely quantify the amounts of anti-RBD antibodies in individuals infected with SARS-CoV-2.

18 Feb 2022

Study shows mink can be infected by Omicron and efficiently transmit the virus to other mink

Researchers have been examining the pathology and spread of the Omicron variant in mink.

18 Feb 2022

Role of quantitative, multiplexed, targeted proteomics in determining variant-specific SARS-CoV-2 antibody response

Researchers developed a ‘bait and capture’ system which was further followed by a multiplexed and targeted proteomic liquid chromatography-tandem mass spectrometry analyses for the comparison of immune correlates in response to vaccination, natural infection, as well as protection against SARS-CoV-2 variants.

18 Feb 2022

Study finds antigenic profile of Omicron RBD is distinct from the prior SARS-CoV-2 variants of concern

A new study aimed to clarify whether extensive RBD mutations could affect the magnitude and immunodominance hierarchy of the host antibody response.

18 Feb 2022

Exposure to endocrine disrupting mixtures during pregnancy impacts children's brain development

By linking human population studies with experiments in cell and animal models, researchers have provided evidence that complex mixtures of endocrine disrupting chemicals impact children's brain development and language acquisition.

17 Feb 2022

COVID test-to-return may help shorten time away from school

In a recent study posted to the medRxiv* preprint server, a test-to-return approach for students in isolation is explored for its utility in sorting out students who can safely return to school without jeopardizing others, from those with a high viral load.

17 Feb 2022

New insights could help long-term care facilities enhance infection prevention and control measures

Findings from a study published today in the American Journal of Infection Control provide new insights that could help long-term care facilities assess the cleanliness of high-touch surfaces, and thereby enhance infection prevention and control measures designed to prevent serious diarrheal diseases and deaths among their residents.

17 Feb 2022

Dual access veno-arterial approach increases mortality rate for babies in respiratory failure put on ECMO

The current trend of using two cannulas to place most newborns in respiratory failure on life-sustaining ECMO, one in the right internal jugular vein and a second in the right common carotid artery, rather than a single cannula in the right internal jugular, increases mortality rates for these babies, investigators report.

17 Feb 2022

How accurate are rapid antigen COVID tests?

A new study updates the state of knowledge about antigen rapid diagnostic tests (Ag-RDT) in the diagnosis of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Feb 2022

Trial of early antiviral therapy for COVID-19 shows no significant benefit

A new preprint research paper examines the efficacy of using three antivirals in various combinations in early infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Feb 2022

Ensitrelvir, a novel SARS-CoV-2 antiviral

S-217622 reduces the viral load and help alleviate the severity of SARS-CoV-2 in infected hamsters.

17 Feb 2022

Faster transmission of SARS-CoV-2 Delta variant in households compared to Alpha

Researchers assess how fast the SARS-CoV-2 Alpha and Delta variants transmit from transmission data in a household study.

17 Feb 2022

New finding may aid in development of vaccines against future animal-to-human viral diseases

A future vaccine providing protection against a wide range of coronaviruses that jump from their original animal hosts to humans - including SARS-CoV-2, the cause of COVID-19 - may be possible, say Johns Hopkins Medicine researchers, based on findings from their recent study.

17 Feb 2022

Study reveals mechanisms associated with severe blood clotting in COVID-19 patients

After studying blood samples from 244 patients hospitalized for COVID-19, a group of researchers, including those who work at the National Institutes of Health, identified “rogue antibodies” that correlate with severe illness and may help explain mechanisms associated with severe blood clotting.

17 Feb 2022

Respiratory News and Research

mRNA vaccine-induced antibodies shown to be more effective in neutralizing SARS-CoV-2 and its variants than natural immunity

Study shows mink can be infected by Omicron and efficiently transmit the virus to other mink

Role of quantitative, multiplexed, targeted proteomics in determining variant-specific SARS-CoV-2 antibody response

Study finds antigenic profile of Omicron RBD is distinct from the prior SARS-CoV-2 variants of concern

Exposure to endocrine disrupting mixtures during pregnancy impacts children's brain development

COVID test-to-return may help shorten time away from school

New insights could help long-term care facilities enhance infection prevention and control measures

Dual access veno-arterial approach increases mortality rate for babies in respiratory failure put on ECMO

How accurate are rapid antigen COVID tests?

Trial of early antiviral therapy for COVID-19 shows no significant benefit

Ensitrelvir, a novel SARS-CoV-2 antiviral

Faster transmission of SARS-CoV-2 Delta variant in households compared to Alpha

New finding may aid in development of vaccines against future animal-to-human viral diseases

Study reveals mechanisms associated with severe blood clotting in COVID-19 patients

Study explores the high viral loads of SARS-CoV-2 Delta and Alpha variants

Study explores humoral and cellular immunity conferred by second and third COVID-19 BNT162b2 vaccination in elderly

COVID-19 vaccine-induced immunity in heart and kidney solid organ transplant recipients

Identifying direct and indirect effects of SARS-CoV-2 pandemic on mortality in the US

ChAdOx1 vaccine found to protect Syrian hamsters against SARS-CoV-2 variants

Study explores differential immune responses against SARS-CoV-2 in adults and children

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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