Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Study reveals dual effects of new osteoporosis therapy on bone tissue

Sclerostin is a protein produced by osteocytes in the bone that inhibits bone formation. A recent analysis of results from a clinical trial reveals the beneficial effects of romosozumab, an antibody therapy that targets sclerostin, on bone tissue in postmenopausal women with osteoporosis.

26 Jun 2019

Stability Testing of Therapeutic Proteins using DLS and Machine Learning

PIPPI scientists from different fields are developing methodologies, tools, and databases to guide the rational formulation of robust protein-based therapeutics. Their overall goal is to develop a database to guide product formulation development.

From Waters | Wyatt Technology 26 Jun 2019

Study discusses beneficial effects of antibody therapy that targets sclerostin

26 Jun 2019

Expedeon AG launches Lightning-Link Metal Labeling Kits to support single cell analysis

Expedeon AG announced today it has introduced Lightning-Link Metal Labeling Kits for use in multiple immunoassay-based applications to support single cell analysis.

24 Jun 2019

New chemoimmunotherapy regimen for aggressive form of lymphoma gets FDA approval

A cancer therapy based on the work of Ben Seon, PhD, at Roswell Park Comprehensive Cancer Center has been approved by the U.S. Food and Drug Administration for patients with an aggressive form of non-Hodgkin lymphoma.

24 Jun 2019

New chief medical officer appointed for Cancer Research UK’s Centre for Drug Development

Professor Peter Johnson will be the new chief medical officer for Cancer Research UK’s Centre for Drug Development, it was announced today (Tuesday).

19 Jun 2019

ChIP-seq kit maximizes chromatin-antibody binding and capture

Optimizing protein orientation for maximum chromatin-antibody binding and capture enables Chromatrap® ChIP-seq kits to offer market leading sensitivity.

From Chromatrap® - Porvair Sciences Ltd 19 Jun 2019

Scientists develop universal FACS-based approach to heterogenous cell sorting, propelling organoid research

Researchers have developed three novel FACS protocols that can be used to isolate neural progenitors, astrocytes, and neurons from infected cerebral organoids.

19 Jun 2019

Newly discovered antibody broadly inhibits multiple strains of pandemic norovirus

Researchers at the University of North Carolina at Chapel Hill Gillings School of Global Public Health and their colleagues at the University of Texas at Austin and the National Institutes of Health Vaccine Research Center have discovered an antibody that broadly inhibits multiple strains of pandemic norovirus, a major step forward in the development of an effective vaccine for the dreaded stomach virus.

19 Jun 2019

TEST-1 Using SPR to Confront the Antibody Reproducibility Crisis

It is important to validate parameters of purchased antibodies with SPR to ensure they are high-quality and also useful for your application,

From Nicoya Lifesciences 19 Jun 2019

Breastmilk antibody necessary to prevent necrotizing enterocolitis in preterm infants

A new study from the University of Pittsburgh and UPMC Children's Hospital of Pittsburgh finds that an antibody in breastmilk is necessary to prevent necrotizing enterocolitis (NEC)- an often deadly bacterial disease of the intestine-in preterm infants.

17 Jun 2019

A 'homing beacon' for cancer drugs

Killing tumor cells while sparing their normal counterparts is a central challenge of cancer chemotherapy. If scientists could put a “homing beacon” in tumors, they could attract these medicines and reduce side effects caused by the drugs acting on healthy cells.

17 Jun 2019

Researchers examine transport mechanism of bacterial membrane protein

An international research team has investigated the transport mechanism of a bacterial membrane protein using an artificially produced antibody fragment.

17 Jun 2019

Novel insight could improve vaccines that protect pregnant women and newborns

A team led by Duke Health scientists has identified a cellular process that could lead to the development of safer and more effective vaccines that protect pregnant women as well as their newborns from dangerous infections.

16 Jun 2019

Research suggests new way to improve the efficacy of arthritis drug

Attaching a removable lock to an arthritis drug can make it safer and more effective, according to a new study publishing June 13 in the open-access journal PLOS Biology led by Wen-Wei Lin of Kaohsiung Medical University, Taiwan.

From PLOS ONE 14 Jun 2019

Developing new immunotherapeutic treatments for emerging viral diseases

Emerging viral diseases is a term used to refer to diseases caused by pathogens such as the Ebola virus. Whilst vaccines can protect people against these diseases, there is an urgent need for treatment options after infection.

14 Jun 2019

Antibodies could cause arthritic pain

Antibodies that exist in the joints before the onset of rheumatoid arthritis can cause pain even in the absence of arthritis, researchers from Karolinska Institutet in Sweden report.

13 Jun 2019

Electronic consultations in allergy and immunology may reduce need for specialist visits

A study from Massachusetts General Hospital researchers finds that electronic consultations in allergy and immunology can simplify the process of providing the most appropriate care, often reducing the need for in-person specialist visits.

12 Jun 2019

Genetic variations linked with persistence of immunity after routine childhood vaccination

A genome-wide search in thousands of children in the UK and Netherlands has revealed genetic variants associated with differing levels of protective antibodies produced after routine childhood immunizations.

12 Jun 2019

Fibrinogen a key player in health and disease, says new study

A new study from the University of Alberta demonstrated that the blood clotting protein called fibrinogen also regulates MMP-2, an enzyme involved in immunity and in clot formation inside blood vessels. Prolonged MMP-2 inhibition could potentially produce a deficiency state with severe consequences.

12 Jun 2019