immunity News and Research

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Study shows how immune cells quickly switch to attack mode

Macrophages have two faces: In healthy tissue, they perform important tasks and support their environment. However during an infection, they stop this work and hunt down the pathogens instead.

17 Dec 2019

Study finds new drivers of destructive inflammation

Scientists describe in Nature Immunology an entirely new molecular process in mice that triggers T cell-driven inflammation and causes different auto-immune diseases.

17 Dec 2019

More than a third of low- and middle-income countries face double burden of malnutrition

A new approach is needed to help reduce undernutrition and obesity at the same time, as the issues become increasingly connected due to rapid changes in countries' food systems.

16 Dec 2019

Researchers identify novel genes associated with severity of peanut allergy

Researchers at the Icahn School of Medicine at Mount Sinai have identified novel genes associated with the severity of peanut allergy, as well as ways in which these genes interact with other genes during allergic reactions.

14 Dec 2019

Measles comeback attributed to anti-vaccination campaigns

Measles, a viral infection that is highly contagious is making a comeback over the past few years in several developed as well as developing nations. This is mainly due to the decline in vaccination rates that protect the community and the unimmunized.

12 Dec 2019

Single, higher dose of Zika vaccine to pregnant female mice protects both mom and fetus

Researchers from The University of Texas Medical Branch at Galveston showed, for the first time, that a single, higher dose of vaccination to a pregnant mouse safely protects both her and her fetus from the Zika virus.

12 Dec 2019

UA physician-scientist to study how common stressors affect the aging process

The human body gets stressed every single day. Whether we contract a minor infection or even argue with a loved one, these small stressors impact our immune system.

10 Dec 2019

Some phages employ new strategy to avoid becoming the next casualty of DNA-dicing enzymes

Bacteria and the viruses that infect them are engaged in a molecular arms race as ancient as life itself. Evolution has equipped bacteria with an arsenal of immune enzymes, including CRISPR-Cas systems, that target and destroy viral DNA. But bacteria-killing viruses, also known as phages, have devised their own tools to help them outmaneuver even the most formidable of these bacterial defenses.

9 Dec 2019

Important biomarker may help in determining prognosis of brain cancer patients

A common virus that is harmless to most individuals may produce an important biomarker in determining the prognosis of brain cancer patients, according to a recent study published by a student researcher at the University of Cincinnati.

9 Dec 2019

Piglet study shows probiotics and prebiotics work differently in girls and boys

The team from the Universities of Bristol and Reading found that 28-day old piglets produced very different levels of immune cells, antibodies and other immune-associated molecules depending on their sex, contradicting previous evidence suggesting that the difference in immunity begins during puberty.

9 Dec 2019

Typhoid conjugate vaccine proves its worth in the field

A new typhoid conjugate vaccine (TCV) that has been approved by the World Health Organization (WHO) Global Advisory Committee on Vaccine Safety has proved extremely effective in both young children and adults in a high-endemicity area for the first time. With almost 82% of recipients showing protection against typhoid, the vaccine promises to help control this deadly disease that claims up to 160,000 of its 11 million victims each year.

5 Dec 2019

Transitional T cells could help improve cancer immunotherapy

In chronic viral infections and cancer, T cell dysfunction is sure to be observed. A new study to be published in the journal Immunity shows that before these cells are completely exhausted, there is a transitory stage in which some cells are present with features that are characteristic of neither the stem-like T cells nor the mature but exhausted T cells.

4 Dec 2019

Hybrid antibiotics show promising results in eradicating deadly staph infections

Eradicating deadly staph using a new breed of antibiotics has revealed promising results in research released by QUT, to help overcome one of the biggest modern medical challenges.

4 Dec 2019

Study: TBK1 protein promotes cancer development, suppresses immune response to the disease

Researchers at The University of Texas MD Anderson Cancer Center have found that a protein involved in immune response to microbes also can fuel cancer development and suppress immune response to the disease.

3 Dec 2019

Stem cells do help restore heart function – but in a different way

A new study published in the journal Nature shows that stem cells do work well to repair the damaged heart – but in an entirely different manner than was originally supposed. The study shows that stem cells, whether living or dead, when injected into the area of damage in the heart in mice, activate an intense acute inflammation. This triggers the classic wound healing response which finally results in the partial or complete recovery of mechanical function of the injured area.

28 Nov 2019

New compound may enhance dengue vaccine efficacy by simulating amino acid deficiency

A new study published in the journal Science Signaling on November 26, 2019, describes a mouse experiment, in which the immune response to the dengue vaccine was boosted when the mice were first given halofuginone, a plant compound that is well known to herbalists.

27 Nov 2019

Research shows how gut microbes affect stomach flu

A new study shows that gut microbes can modulate the severity of norovirus infection (the stomach flu, or the winter vomiting bug), based on the gut location first affected. Published in the journal Nature Microbiology on November 25, 2019, the study indicates new possibilities to treat norovirus infection.

26 Nov 2019

Sheffield research receives £800k to develop new gene therapy to treat CVD

Cardiac research in Sheffield has received a major boost from the British Heart Foundation in the form of an £800,000 award to develop a new gene therapy to treat cardiovascular disease (CVD).

26 Nov 2019

Key mechanism identified for how antiviral immune responses reprogram liver metabolism

Researchers at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences identified a key mechanism for how antiviral immune responses reprogram liver metabolism. Their recent study, which was published in the renowned scientific journal Immunity, investigated the communication between inflammation and liver metabolism during chronic viral infection.

26 Nov 2019

Newly developed personalized vaccine system could delay onset of pancreatic cancer

Researchers from Queen Mary University of London and Zhengzhou University have developed a personalized vaccine system that could ultimately delay the onset of pancreatic cancer. The study provides strong proof-of-concept for the creation of a vaccine for cancer prevention in individuals at high risk of developing this disease and to slow down tumor growth in patients who are affected by it.

26 Nov 2019

immunity News and Research

Study shows how immune cells quickly switch to attack mode

Study finds new drivers of destructive inflammation

More than a third of low- and middle-income countries face double burden of malnutrition

Researchers identify novel genes associated with severity of peanut allergy

Measles comeback attributed to anti-vaccination campaigns

Single, higher dose of Zika vaccine to pregnant female mice protects both mom and fetus

UA physician-scientist to study how common stressors affect the aging process

Some phages employ new strategy to avoid becoming the next casualty of DNA-dicing enzymes

Important biomarker may help in determining prognosis of brain cancer patients

Piglet study shows probiotics and prebiotics work differently in girls and boys

Typhoid conjugate vaccine proves its worth in the field

Transitional T cells could help improve cancer immunotherapy

Hybrid antibiotics show promising results in eradicating deadly staph infections

Study: TBK1 protein promotes cancer development, suppresses immune response to the disease

Stem cells do help restore heart function – but in a different way

New compound may enhance dengue vaccine efficacy by simulating amino acid deficiency

Research shows how gut microbes affect stomach flu

Sheffield research receives £800k to develop new gene therapy to treat CVD

Key mechanism identified for how antiviral immune responses reprogram liver metabolism

Newly developed personalized vaccine system could delay onset of pancreatic cancer

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