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Researchers develop potentially safer and more cost-effective therapeutics against West Nile virus

An international research group led by Arizona State University professor Qiang "Shawn" Chen has developed a new generation of potentially safer and more cost-effective therapeutics against West Nile virus and other pathogens.

29 Mar 2014

Physicians suspect that chemotherapy can accelerate aging process

Physicians have long suspected that chemotherapy can accelerate the aging process in patients treated for cancer. Using a test developed at UNC Lineberger Comprehensive Cancer Center to determine molecular aging, UNC oncologists have directly measured the impact of anti-cancer chemotherapy drugs on biological aging.

29 Mar 2014

Researchers identify plant compounds that may support delivery of chemotherapy treatments

Researchers at Plant & Food Research have identified plant compounds present in carrots and parsley that may one day support more effective delivery of chemotherapy treatments.

28 Mar 2014

Research findings help explain rare genetic disorder that causes immunodeficiency syndrome

IRCM researchers led by Javier M. Di Noia, PhD, uncovered a new function of AID, a crucial enzyme for the immune response. The discovery, recently published by the scientific journal Proceedings of the National Academy of Sciences, helps explain a rare genetic disorder that causes an immunodeficiency syndrome.

28 Mar 2014

Cells measure surface area using cdr2p protein

One of the scientists who revealed how plants "do maths" can now reveal how cells take measurements of size. Size is important to cells as it determines when they divide.

28 Mar 2014

IRB researchers identify dual role of p38 protein in colon cancer

A team headed by Angel R. Nebreda at the Institute for Research in Biomedicine identifies a dual role of the p38 protein in colon cancer. The study demonstrates that, on the one hand, p38 is important for the optimal maintenance of the epithelial barrier that protects the intestine against toxic agents, thus contributing to decreased tumour development.

28 Mar 2014

Discovery could lead to new medications for cancer, say Rice University scientists

A new understanding of proteins at the nexus of a cell's decision to survive or die has implications for researchers who study cancer and age-related diseases, according to biophysicists at the Rice University-based Center for Theoretical Biological Physics.

28 Mar 2014

Staging model, biomarker proposed for bipolar disorder

Researchers have proposed a model of early and late staging for patients with bipolar disorder according to functioning, number of episodes, age at onset and the time elapsed since first episode.

27 Mar 2014

New biomarker test accurately estimates mortality risk in patients with septicemia

Septic shock is a severe systemic infection and major cause of death for the old and young alike. Unfortunately, researchers say testing new drug regimens to stop the infection is confounded because clinical trials include patients who are either too sick to be saved by experimental therapies or not sick enough to warrant the treatments.

27 Mar 2014

RuiYi declares $15M Series B financing to advance monoclonal antibodies targeting GPCR receptors

RuiYi, Inc. announced today a $15 million Series B financing by existing investors: 5AM Ventures, Versant Ventures, Apposite Capital, SR One, the independent corporate healthcare venture capital fund of GlaxoSmithKline, Merck Serono Ventures, the strategic corporate venture fund of Merck Serono, and Aravis SA.

27 Mar 2014

New drug multiplies analgesic effect of opioids without increasing constipation

Scientists from the University of Granada have taken part, alongside the Esteve laboratory, in the development of a new drug that multiplies the analgesic effect of opioids (drugs for treating intense pain), without increasing constipation, one of the most common side-effects of these drugs, among which is morphine.

27 Mar 2014

Study to understand how protein motor works for development of targeted cancer therapies

Researchers at Warwick Medical School have shown for the first time how a protein motor, Kif15, uses acrobatic flexibility to navigate within the mitotic spindle. Understanding how it works could prove vital for the development of targeted cancer therapies.

27 Mar 2014

Research points strong reason to develop new class of antidepressant drug

Scientists have shown for the first time that a chemical in the brain called galanin is involved in the risk of developing depression.

From The University of Manchester 27 Mar 2014

Study: Genetics could explain why environmental exposures can trigger onset of rheumatoid arthritis

A new international study has revealed how genetics could explain why different environmental exposures can trigger the onset of different forms of rheumatoid arthritis.

From The University of Manchester 27 Mar 2014

Study points to potential culprit that kills motor neurons in ALS

Amyotrophic lateral sclerosis, also known as Lou Gehrig's disease, is marked by a cascade of cellular and inflammatory events that weakens and kills vital motor neurons in the brain and spinal cord. The process is complex, involving cells that ordinarily protect the neurons from harm. Now, a new study by scientists in The Research Institute at Nationwide Children's Hospital points to a potential culprit in this good-cell-gone-bad scenario, a key step toward the ultimate goal of developing a treatment.

27 Mar 2014

Study: Dab2 can exhibit neuroprotective effects in Alzheimer's by regulating TGF-β1/SMAD signaling

Transforming growth factor-beta (TGF-β) type II receptor (TβRII) levels are extremely low in the brain tissue of patients with Alzheimer's disease.

27 Mar 2014

Johns Hopkins researchers identify protein that regulates the body's immune response to CMV

Infectious disease specialists at the Johns Hopkins Children's Center have identified a protein that regulates the body's immune response to cytomegalovirus (CMV), a common pathogen that causes lifelong infections and can lead to devastating illness in newborns and those with weakened immune systems.

27 Mar 2014

New international partnership aims to increase wheat yields by 50% by 2034

A new international partnership aims to increase wheat yields by 50 percent by 2034. This will address demand for wheat - one of the world's most important crops - that is growing much faster than production.

26 Mar 2014

Low dose injections of artificial properdin provides protection against septic diseases in mice

Breakthrough MRC-funded study from University of Leicester shows low dose injections of artificial properdin provides substantial protection against septic diseases in mice

26 Mar 2014

Adaptimmune awarded £2.1 million grant to expedite development of engineered T cell therapy

Adaptimmune today announced that it has been awarded a grant of £2.1 million from the Biomedical Catalyst Fund, managed by the UK’s innovation agency the Technology Strategy Board and the Medical Research Council. The prestigious award will expedite the development of Adaptimmune’s second engineered T cell therapy programme into the clinic in triple negative breast cancer.

26 Mar 2014

G Protein News and Research

Researchers develop potentially safer and more cost-effective therapeutics against West Nile virus

Physicians suspect that chemotherapy can accelerate aging process

Researchers identify plant compounds that may support delivery of chemotherapy treatments

Research findings help explain rare genetic disorder that causes immunodeficiency syndrome

Cells measure surface area using cdr2p protein

IRB researchers identify dual role of p38 protein in colon cancer

Discovery could lead to new medications for cancer, say Rice University scientists

Staging model, biomarker proposed for bipolar disorder

New biomarker test accurately estimates mortality risk in patients with septicemia

RuiYi declares $15M Series B financing to advance monoclonal antibodies targeting GPCR receptors

New drug multiplies analgesic effect of opioids without increasing constipation

Study to understand how protein motor works for development of targeted cancer therapies

Research points strong reason to develop new class of antidepressant drug

Study: Genetics could explain why environmental exposures can trigger onset of rheumatoid arthritis

Study points to potential culprit that kills motor neurons in ALS

Study: Dab2 can exhibit neuroprotective effects in Alzheimer's by regulating TGF-β1/SMAD signaling

Johns Hopkins researchers identify protein that regulates the body's immune response to CMV

New international partnership aims to increase wheat yields by 50% by 2034

Low dose injections of artificial properdin provides protection against septic diseases in mice

Adaptimmune awarded £2.1 million grant to expedite development of engineered T cell therapy

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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