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Study provides new insights into potential outcomes of Zika virus infection

Using a relevant animal model (pigs), University of Saskatchewan researchers have shown that mild Zika virus infection in fetuses can cause abnormal brain development in apparently healthy young animals.

15 Nov 2019

Research breakthrough may lead to new therapeutic targets for cancers

Computational modeling is the use of computers to simulate and study the behavior of complex systems. Computational approaches are widely adopted in the bioimedical sciences and can be used to sift through large volumes of complex data to extract recurrent patterns that may point to a disease's causes and effects.

15 Nov 2019

Mining 'darkest' parts of the genome in cancer cells yields gold

Mining the rich uncharted territory of the genome or genetic material of a cancer cell has yielded gold for Princess Margaret scientists: new protein targets for drug development against prostate cancer.

15 Nov 2019

Key Alzheimer's gene variants act differently among Caribbean Hispanics based on ancestry

Researchers looking to uncover the mysteries of Alzheimer's disease have revealed new insights from old variants.

15 Nov 2019

Non-coding enhancer DNA may be key for identifying genetic risk in neurological conditions

One might think that the primary cause of most genetically linked diseases comes from mutations in coding DNA -- alterations in coding regions of the genome that can lead directly to changes in the expression of particular proteins important for a healthy body.

14 Nov 2019

Altering malarial parasite genes to prevent malaria

Malaria is a mosquito-borne disease caused by the parasitic organism called Plasmodium, of which there are several types that cause the different kinds of malarial fever. This age-old infection still kills over 400,000 people every year, all over the world. A new study published in the journal Cell on November 14, 2019, shows how a simple tweaking of the genes of this organism could quite conceivably lead to the elimination of this disease altogether.

14 Nov 2019

New insights into how immune system and inflammation play a role in PD

Relatively new research findings indicating that the earliest stages of Parkinson's disease (PD) may occur in the gut have been gaining traction in recent years. In a review published in the Journal of Parkinson's Disease, Tomasz Brudek, PhD, evaluates evidence for the association between inflammatory bowel disease (IBD) and PD and proposes directions for future research.

14 Nov 2019

Thermo Fisher Scientific becomes member of the Pistoia Alliance

Thermo Fisher Scientific, the world leader in serving science, has become a member of the Pistoia Alliance, a global, not-for-profit alliance of life science companies, vendors, publishers and academic groups working to lower barriers to innovation in life science and healthcare R&D through pre-competitive collaboration.

From Thermo Fisher Scientific Inc. 14 Nov 2019

Caution: blood infections traced to probiotics

Probiotics aren’t harmless, says a new study published on November 7, 2019 in the journal Nature Medicine. In fact, some patients may be put at serious risk by the bacteria in probiotics. Doctors should weigh the risks of probiotics in severely ill or immunocompromised patients before prescribing them, as their benefits may be significantly smaller than the danger in such situations.

13 Nov 2019

Tulane virus needs intracellular calcium to replicate

Some gastrointestinal viruses need calcium. They need calcium ions to carry out several essential aspects of viral life, such as entry into host cells, genome replication and building new viruses to invade other cells. The cells invaded by viruses also use calcium. They use it as signals to regulate many of the cells' own processes, but viruses can takeover cellular calcium signaling to satisfy their own needs.

13 Nov 2019

'Smart toilets' may work as real-time method of monitoring health

Wearable, smart technologies are transforming the ability to monitor and improve health, but a decidedly low-tech commodity - the humble toilet - may have potential to outperform them all.

13 Nov 2019

New study sounds a note of caution in using probiotics in ICU

It's become common for patients in the intensive care unit (ICU), both children and adults, to receive probiotics. Often, they are started at home to counteract diarrhea caused by antibiotics. There is also interest in using probiotics proactively in the ICU. A large multicenter clinical trial in Canada is testing whether probiotics would prevent ventilator-associated pneumonia in adult ICU patients.

12 Nov 2019

Polygenic risk score improves psychosis risk prediction, study finds

A new study led by researchers at the University of North Carolina at Chapel Hill has found that that using a polygenic risk score based on data from genome-wide association studies improves psychosis risk prediction in persons meeting clinical high-risk criteria.

12 Nov 2019

Rutgers researcher receives $600,000 grant to study chronic lymphocytic leukemia

Rutgers Cancer Institute of New Jersey researcher Hossein Khiabanian, PhD, has received a $600,000 Translational Award from the V Foundation for Cancer Research to study chronic lymphocytic leukemia with the aim of developing research models that may help investigators better understand how CLL cells are influenced by new therapies.

11 Nov 2019

Chronic sleep deprivation linked to increased biological aging and cardiovascular disease risk

Getting a good night's sleep is important and insufficient sleep has been linked to poor health in many studies.

11 Nov 2019

New point-of-care medical device rapidly and accurately detects viruses

The gene-editing tool CRISPR has been heralded as a scientific miracle destined to eradicate diseases from sickle-cell anemia to cancer, or decried as "the genetic scissors that tailor the human gene pool," an ethically risky technology driving us toward a designer babies.

11 Nov 2019

Zika virus causes altered immune responses and brain abnormalities in healthy pig offspring

Zika virus infection in the womb produces altered immune responses and sex-specific brain abnormalities in apparently healthy pig offspring, according to a study published November 14 in the open-access journal PLOS Pathogens by Uladzimir Karniychuk of the University of Saskatchewan, and colleagues.

From PLOS ONE 11 Nov 2019

Atmospheric and environmental changes linked to organ-specific lupus flares

New research findings presented at the 2019 ACR/ARP Annual Meeting found a strong association between changes in atmospheric and environmental variables 10 days before a clinic visit and organ-specific lupus flares in patients with systemic lupus erythematosus.

10 Nov 2019

Study shows how glucocorticoid hormones control sugar and fat levels over the course of 24 hours

For the first time, a study led by researchers at Helmholtz Zentrum München and the German Center for Diabetes Research shows how glucocorticoid hormones, such as cortisol, control sugar and fat levels differently during day and night, feeding and fasting, rest and activity, over the course of 24 hours.

10 Nov 2019

Hitachi and CLB in Lyon-France announce research collaboration to fight against cancer with AI

Hitachi, Ltd. and Centre Leon Berard (CLB), a leading French Comprehensive Cancer Center in Lyon-France, announced today that they have entered into an agreement to jointly promote research and development aimed at improving the efficiency of diagnosis and treatment of cancer and established a new research laboratory called Hitachi Lyon Lab on the CLB site, starting November 5th.

8 Nov 2019

Genome News and Research

Study provides new insights into potential outcomes of Zika virus infection

Research breakthrough may lead to new therapeutic targets for cancers

Mining 'darkest' parts of the genome in cancer cells yields gold

Key Alzheimer's gene variants act differently among Caribbean Hispanics based on ancestry

Non-coding enhancer DNA may be key for identifying genetic risk in neurological conditions

Altering malarial parasite genes to prevent malaria

New insights into how immune system and inflammation play a role in PD

Thermo Fisher Scientific becomes member of the Pistoia Alliance

Caution: blood infections traced to probiotics

Tulane virus needs intracellular calcium to replicate

'Smart toilets' may work as real-time method of monitoring health

New study sounds a note of caution in using probiotics in ICU

Polygenic risk score improves psychosis risk prediction, study finds

Rutgers researcher receives $600,000 grant to study chronic lymphocytic leukemia

Chronic sleep deprivation linked to increased biological aging and cardiovascular disease risk

New point-of-care medical device rapidly and accurately detects viruses

Zika virus causes altered immune responses and brain abnormalities in healthy pig offspring

Atmospheric and environmental changes linked to organ-specific lupus flares

Study shows how glucocorticoid hormones control sugar and fat levels over the course of 24 hours

Hitachi and CLB in Lyon-France announce research collaboration to fight against cancer with AI

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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