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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Researchers partially restore lost function of isolated cystic fibrosis lung cells

In experiments with isolated cystic fibrosis lung cells, University of Alabama at Birmingham researchers and colleagues from two other institutions have partially restored the lost function of those cells.

26 May 2016

Scientists study how viral evolution occurs

Viruses evolve quickly. A small tweak to the genetic makeup of a mostly mild strain of influenza can give rise to the next pandemic. An equally small change to the same strain in a different setting can fade it into obscurity.

24 May 2016

Scientists take key step towards understanding link between obesity and physically distant diseases

Obesity is on the rise throughout the world, and in some developed countries two-third of the adult population is either overweight or obese. This brings with it an increased risk of serious conditions such as heart disease, stroke, cancer and osteoarthritis.

23 May 2016

Wresting back control of CHI3L1 protein could stave off cancer spread in mice

For cancer to spread, the cells that take off into the bloodstream must find a tissue that will permit them to thrive. They don't just go looking, though. Instead, they actively prepare the tissue, in one case by co-opting a protein that suppresses defenses the body would otherwise mount.

21 May 2016

LIGR-Seq tool opens door to developing new understanding of ncRNA function

What used to be dismissed by many as "junk DNA" is back with a vengeance as growing data points to the importance of non-coding RNAs (ncRNAs) -- genome's messages that do not code for proteins -- in development and disease.

21 May 2016

New study aims to identify biomarkers linked to cartilage degradation in OA patients

Joint injury can lead to post-traumatic osteoarthritis (PTOA). In fact, about half of all people who rupture the anterior cruciate ligament (ACL) in their knee will develop PTOA within 10-20 years of the injury.

20 May 2016

Gene editing technology helps excise segment of HIV-1 DNA from genomes of living animals

Using gene editing technology, researchers at the Lewis Katz School of Medicine at Temple University have, for the first time, successfully excised a segment of HIV-1 DNA - the virus responsible for AIDS - from the genomes of living animals.

20 May 2016

Landmark study characterizes evolution of symptoms, signs of acute HIV infection

Acute HIV infection (AHI) contributes significantly to HIV transmission and may be important for intervention strategies seeking to reduce incidence and achieve a functional cure.

19 May 2016

Maintaining balance of P1 and P2 isoforms vital for reducing colon cancer, colitis risk

Inflammatory bowel disease (IBD), of which Crohn's disease and ulcerative colitis are the main types, is on the increase in the United States, affecting more than 1.6 million people and explaining perhaps the increase in advertisements offering treatments and cures.

18 May 2016

Ipsen partners with IMCB to advance understanding and research of Botulinum Neurotoxin Biology

Ipsen S.A., a global specialty-driven pharmaceutical company, and the Institute of Molecular and Cell Biology (IMCB), a research institute under the aegis of the Agency for Science, Technology and Research (A*STAR), Singapore, today announced the signature of a research partnership to study the intracellular trafficking of botulinum neurotoxins (BoNTs) within neurons.

16 May 2016

New optimised PCR tests for reliable diagnosis of Zika virus

DZIF scientists from the University of Bonn have shown that not all conventional Zika virus molecular diagnostic tests for are sufficiently reliable. They developed optimised assays and a control for quantifying viruses in blood and urine.

13 May 2016

Researchers develop novel ss-siRNAs to turn off disease-related genes

Combining the therapeutic potential and advantages of existing oligonucleotide-based approaches to turn off disease-related genes, a type of single-stranded silencing RNAs (ss-siRNAs) has shown significantly improved potency and activity.

13 May 2016

Cryo-EM technique allows researchers to visualize large transcription PICs at near-atomic resolution

An unprecedented molecular view of the critical early events in gene expression, a process essential for all life, has been provided by researchers at Georgia State University, the University of California at Berkeley and Northwestern University.

12 May 2016

Novel NanoDrop One spectrophotometers provide accurate quantitation, sample quality information

Life scientists who work with DNA, RNA and proteins can make educated decisions about sample suitability for experiments using the new standalone microvolume spectrophotometers.

From Thermo Fisher Scientific Inc. 12 May 2016

EvOx Therapeutics raises £10m to target new therapeutic system for untreatable diseases

Oxford spinout EvOx Therapeutics will harness the body’s own precision communications system to deliver drugs to specific parts of the body, with the aim of treating conditions which are currently untreatable including those affecting the brain, as well as autoimmune diseases and cancers.

11 May 2016

Simultaneous DNA, RNA and protein analysis to enhance cancer immunology studies: an interview with Dr Joseph Beechem

Cancer immunology is all about how your immune cells are going to fight and kill your tumor cells. If you look at the pure genetic code of a T-cell that's going to kill your tumor compared to the same cell that has been “put-to-sleep” (by the tumor), the pure genetic DNA content of those two cells are identical.

From NanoString Technologies 11 May 2016

lncRNA in placenta may help protect unborn baby from invading pathogens

The human placenta is an organ unlike any other. During the course of nine months it is formed by the embryo, sustains life and then is shed.

10 May 2016

MGH researchers develop device to rapidly diagnose health-care-associated infections

A team of Massachusetts General Hospital investigators has developed a device with the potential of shortening the time required to rapidly diagnose pathogens responsible for health-care-associated infections from a couple of days to a matter of hours.

10 May 2016

TSRI scientists design potential drug candidate to treat triple negative breast cancer

In a development that could lead to a new generation of drugs to precisely treat a range of diseases, scientists from the Florida campus of The Scripps Research Institute have for the first time designed a drug candidate that decreases the growth of tumor cells in animal models in one of the hardest to treat cancers—triple negative breast cancer.

10 May 2016

Scientists develop new technology that helps visualize translation of mRNA into proteins

For the first time, scientists at Albert Einstein College of Medicine have developed a technology allowing them to "see" single molecules of messenger RNA as they are translated into proteins in living mammalian cells. Initial findings using this technology that may shed light on neurological diseases as well as cancer were published online today in Science.

9 May 2016

RNA News and Research

Further Reading

Researchers partially restore lost function of isolated cystic fibrosis lung cells

Scientists study how viral evolution occurs

Scientists take key step towards understanding link between obesity and physically distant diseases

Wresting back control of CHI3L1 protein could stave off cancer spread in mice

LIGR-Seq tool opens door to developing new understanding of ncRNA function

New study aims to identify biomarkers linked to cartilage degradation in OA patients

Gene editing technology helps excise segment of HIV-1 DNA from genomes of living animals

Landmark study characterizes evolution of symptoms, signs of acute HIV infection

Maintaining balance of P1 and P2 isoforms vital for reducing colon cancer, colitis risk

Ipsen partners with IMCB to advance understanding and research of Botulinum Neurotoxin Biology

New optimised PCR tests for reliable diagnosis of Zika virus

Researchers develop novel ss-siRNAs to turn off disease-related genes

Cryo-EM technique allows researchers to visualize large transcription PICs at near-atomic resolution

Novel NanoDrop One spectrophotometers provide accurate quantitation, sample quality information

EvOx Therapeutics raises £10m to target new therapeutic system for untreatable diseases

Simultaneous DNA, RNA and protein analysis to enhance cancer immunology studies: an interview with Dr Joseph Beechem

lncRNA in placenta may help protect unborn baby from invading pathogens

MGH researchers develop device to rapidly diagnose health-care-associated infections

TSRI scientists design potential drug candidate to treat triple negative breast cancer

Scientists develop new technology that helps visualize translation of mRNA into proteins

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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