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Study findings can guide personalized breast cancer therapies based on melatonin

A Brazilian study published in the Journal of Pineal Research describes a group of genes potentially regulated by the hormone melatonin in some types of cancer, especially breast cancer.

8 Dec 2020

Lipid storm in severe COVID-19 linked to high COX/LOX pathway activity

A potentially valuable new study discusses the role of lipids in the hyper-inflammatory phenomena that take place within the lungs of patients with severe or critical COVID-19. Involving a large variety of specialized lipids with biological activity, this process includes the generation and release of pro and anti-inflammatory lipids.

8 Dec 2020

Oligourea-based "fake" peptides enhance options for rational drug design, shows study

Some useful drugs consist of peptides acting on their protein targets. To make them more efficient and stable, scientists have found a way to replace crucial segments of the peptides with ureido units.

8 Dec 2020

Higher degrees of necrosis are inked to poor survival in brain cancer patients

White blood cells are part of many immune system responses in the human body. New research shows that a specific type of those cells may cause brain cancer tissues to die – but that's not good news, according to researchers at Penn State College of Medicine and Penn State Cancer Institute.

8 Dec 2020

Chemotherapy combined with blinatumomab increases survival for patients with Ph-negative B-ALL

A study led by The University of Texas MD Anderson Cancer Center showed that first-line treatment with a regimen of chemotherapy combined with the monoclonal antibody blinatumomab resulted in increased survival and achieved a high rate of measurable residual disease (MRD) negativity for patients who were newly diagnosed with a high-risk form of acute lymphoblastic leukemia (ALL) known as Philadelphia chromosome-negative B-cell ALL (Ph-negative B-ALL).

7 Dec 2020

RNA mutations within common bacterium linked to invasive meningococcal disease

Researchers at Karolinska Institutet in Sweden have come one step closer toward understanding why some people become seriously ill or die from a common bacterium that leaves most people unharmed.

7 Dec 2020

Testing for tumor DNA can help predict risk of relapse after transplant in DLBCL patients

Many patients with diffuse large B-cell lymphoma (DLBCL) can be cured by a transplant using their own blood-forming stem cells, but as many as half eventually relapse.

7 Dec 2020

Henry Ford Health System announces receipt of $16 million gift to Henry Ford Pancreatic Cancer Center

Henry Ford Health System today announced a $16 million gift to its Henry Ford Pancreatic Cancer Center, which was launched in 2018 by an initial $20 million gift from the same donor, who wishes to remain anonymous.

7 Dec 2020

RUDN team suggests new tool to control inflammation in asthma patients with accompanying diseases

A team of immunologists from RUDN University suggested a new tool to control inflammation levels in asthma patients with accompanying diseases.

7 Dec 2020

Study assesses different pipelines for timing mutations in cancer genomes

UCLA Jonsson Comprehensive Cancer Center researchers studying cancer evolution have created a framework to help determine which tool combinations are best for pinpointing the exact timing of DNA mutations in cancer genomes.

7 Dec 2020

Novel modular design approach to antibody nanocage generation

A new study shows the benefits of using computational design to create antibody nanocages that have the required orientation.

7 Dec 2020

Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

Clinical investigators from Hackensack Meridian Health John Theurer Cancer Center (JTCC), a member of the Georgetown Lombardi Comprehensive Cancer Center consortium, are to present updates on treatment advances in multiple myeloma (MM), mantle cell lymphoma (MCL), and other types of B-cell lymphoma (BCL) as well as leukemia at the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, to be held virtually from December 5-8, 2020.

7 Dec 2020

Tumor News and Research

Study findings can guide personalized breast cancer therapies based on melatonin

Lipid storm in severe COVID-19 linked to high COX/LOX pathway activity

Oligourea-based "fake" peptides enhance options for rational drug design, shows study

Higher degrees of necrosis are inked to poor survival in brain cancer patients

Chemotherapy combined with blinatumomab increases survival for patients with Ph-negative B-ALL

RNA mutations within common bacterium linked to invasive meningococcal disease

Testing for tumor DNA can help predict risk of relapse after transplant in DLBCL patients

Henry Ford Health System announces receipt of $16 million gift to Henry Ford Pancreatic Cancer Center

RUDN team suggests new tool to control inflammation in asthma patients with accompanying diseases

Study assesses different pipelines for timing mutations in cancer genomes

Novel modular design approach to antibody nanocage generation

Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

Combination of venetoclax and standard therapies shows promise in high-risk myeloid blood cancers

Researchers identify potential drug combination to treat uveal melanoma

Study identifies multiple important genomic differences in BCL malignancies using genomic ancestry

Researchers develop wound-healing gel based on a substance produced by Trichoderma fungi

β-AR agonist therapy may prevent metastasis in oral squamous cell carcinoma

New tool to predict breast cancer recurrences

Surprising discovery reveals new target for aggressive lung adenocarcinoma

Study: Tumors with high TMB tend to respond better to immune checkpoint inhibitors

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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