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New AI tool tool could be used for rapid, automated anti-epileptic drug testing

By using state-of-the-art technology to analyze patterns of behavior in mice with epilepsy, researchers may be able to better study the disorder and identify potential treatments.

24 Feb 2023

Exploring biodistribution of cannabidiol nanoparticles and nanoemulsion after intrathecal administration

Researchers evaluated the biodistribution of cannabidiol (CBD) emulsion and nanoparticles in the central nervous system (CNS).

24 Feb 2023

Study finds high doses of oral CBD can exacerbate THC’s effects by inhibiting THC metabolism

Researchers compare the pharmacokinetics and pharmacodynamics of oral Δ9-tetrahydrocannabinol-dominant and cannabidiol-dominant cannabis extracts that contained the same Δ9-THC dose (20 mg).

24 Feb 2023

One Texas judge will decide fate of abortion pill used by millions of American women

Federal judges in Texas have delivered time and again for abortion opponents.

24 Feb 2023

New discovery could shift the focus of Parkinson’s disease treatment

Researchers from the University of Queensland have identified that a gene associated with an increased risk of Parkinson's Disease also contributes to a build-up of cell debris in the brain.

24 Feb 2023

A network of interacting proteins created to aid drug discovery

Scientists at Open Targets, EMBL's European Bioinformatics Institute, and GSK are revealing the shared basis of diseases using a map of interacting human proteins.

24 Feb 2023

NQO2 gene as a novel potential target in Parkinson’s disease

A new study under review at the journal Scientific Reports and currently available on the Research Square* preprint server aimed to analyze the toxic effects of 6OHDA along with a related role of NQO2 in murine and human astrocytes.

23 Feb 2023

Mystical and insightful psychedelic experience may be linked to positive mental health outcomes

A more mystical and insightful psychedelic drug experience may be linked to an enduring reduction in anxiety and depression symptoms, according to a new study.

23 Feb 2023

Novel fatty liver organoid models could aid in drug discovery and testing

Researchers from the Organoid group (former Clevers group, Hubrecht Institute) together with researchers from the Princess Máxima Center for pediatric oncology established novel human organoid models of fatty liver disease.

23 Feb 2023

Study identifies a potential new targeted drug for treating acute myeloid leukemia

Targeted drugs have been developed to supplement chemotherapy in the treatment of cancer. These drugs only affect cancer cells, leaving healthy cells alone.

23 Feb 2023

£1.7m NIHR funding to explore how routinely-collected healthcare data can be used to improve clinical guidance

Professor Laurie Tomlinson has been awarded a National Institute for Healthcare Research (NIHR) Research Professorship worth £1.7m to explore how routinely-collected healthcare data can be used to improve clinical guidance.

23 Feb 2023

Study identifies placental growth factor as a biomarker for vascular cognitive impairment

Measuring a key blood molecule may help doctors diagnose whether or how much impaired blood flow to a patient's brain is contributing to dementia or cognitive problems, according to a new study led by a UCLA Health researcher.

23 Feb 2023

Effects of nanoparticles on gouty arthritis in animal models of gout

Researchers performed a systematic review and meta-analysis to explore the effects of nanoparticles on gouty arthritis using animal models.

23 Feb 2023

First-of-its-kind wireless, battery-free bandage accelerates wound healing

Northwestern University researchers have developed a first-of-its-kind small, flexible, stretchable bandage that accelerates healing by delivering electrotherapy directly to the wound site.

22 Feb 2023

Scientists identify mechanisms underlying autoimmunity in Down syndrome

Scientists at the Icahn School of Medicine at Mount Sinai in New York have identified which parts of the immune system go awry and contribute to autoimmune diseases in individuals with Down syndrome.

22 Feb 2023

Analysis examines which non-opioid drugs are best for treating acute low back pain

Acute low back pain is a common cause of disability. An analysis in the Journal of Orthopaedic Research examined which non-opioid drugs are best for treating this condition.

22 Feb 2023

A bitter battle over the ‘orphan drug’ program leaves patients’ pocketbooks at risk

A prescription drug that helps Lore Wilkinson walk and talk despite a rare muscle disease cost her so little for more than a decade that she didn't even use her insurance to pay for it.

22 Feb 2023

New analysis shows how convalescent plasma can be used as effective, low-cost COVID-19 treatment

Three years into the COVID-19 pandemic, new variant outbreaks continue to fuel economic disruptions and hospitalizations across the globe.

22 Feb 2023

Study investigates anti-VEGF treatment for inflammatory eye disease in HTLV-1–infected ocular cells

A retrovirus known as human T-cell lymphotropic virus type 1 (HTLV-1) is known to cause a number of diseases, including inflammatory diseases of the eye. Recently, researchers in Japan have investigated an antibody treatment for inflammatory eye disease in ocular cells infected with HTLV-1.

21 Feb 2023

Alternative splicing plays a role in compensating for loss of gene function

Living organisms have a knack for persisting in the face of challenges. For instance, when genes malfunction, organisms may be able to compensate by activating redundant genes with similar functions, called paralogs.

21 Feb 2023

Drugs News and Research

New AI tool tool could be used for rapid, automated anti-epileptic drug testing

Exploring biodistribution of cannabidiol nanoparticles and nanoemulsion after intrathecal administration

Study finds high doses of oral CBD can exacerbate THC’s effects by inhibiting THC metabolism

One Texas judge will decide fate of abortion pill used by millions of American women

New discovery could shift the focus of Parkinson’s disease treatment

A network of interacting proteins created to aid drug discovery

NQO2 gene as a novel potential target in Parkinson’s disease

Mystical and insightful psychedelic experience may be linked to positive mental health outcomes

Novel fatty liver organoid models could aid in drug discovery and testing

Study identifies a potential new targeted drug for treating acute myeloid leukemia

£1.7m NIHR funding to explore how routinely-collected healthcare data can be used to improve clinical guidance

Study identifies placental growth factor as a biomarker for vascular cognitive impairment

Effects of nanoparticles on gouty arthritis in animal models of gout

First-of-its-kind wireless, battery-free bandage accelerates wound healing

Scientists identify mechanisms underlying autoimmunity in Down syndrome

Analysis examines which non-opioid drugs are best for treating acute low back pain

A bitter battle over the ‘orphan drug’ program leaves patients’ pocketbooks at risk

New analysis shows how convalescent plasma can be used as effective, low-cost COVID-19 treatment

Study investigates anti-VEGF treatment for inflammatory eye disease in HTLV-1–infected ocular cells

Alternative splicing plays a role in compensating for loss of gene function

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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