Enzyme News and Research

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Research provides new directions in understanding and fighting glaucoma

Two distinctive handfuls of short molecules that regulate gene expression have been found in the eye fluid of patients with two distinct types of vision degenerating glaucoma.

26 Feb 2018

Scientists reveal new insights into mechanism of gene regulation by 'magic spot'

Using an innovative crystallization technique for studying three-dimensional structures of gene transcription machinery, an international team of researchers, led by scientists at Penn State, has revealed new insights into the long debated action of the "magic spot"--a molecule that controls gene expression in Eschericahia coli and many other bacteria when the bacteria are stressed.

24 Feb 2018

Impairment of interneuron migration could lead to cortical malformation

A team from the University of Liège has discovered a new crosstalk between the migrating inhibitory interneurons and the stem cells that generate the excitatory neurons.

24 Feb 2018

Researchers discover mechanism that could open doors to new treatments for celiac disease

Celiac disease is an autoimmune disorder that affects by some estimates nearly 1 in 100 people. Celiac disease symptoms are triggered by gluten, a protein found in wheat and related plants, but gluten doesn't act alone to cause the digestive symptoms that patients suffer.

23 Feb 2018

Highly sensitive ELISA method for analysis of CET in plasma samples

This article explores the development, full optimization and validation study of a highly sensitive and selective ELISA for determination of cetuximab (CET) in human plasma samples.

23 Feb 2018

Researchers describe important step toward gene therapy for patients with Sandhoff disease

Babies with the rare, deadly genetic disorder Sandhoff disease begin to miss developmental milestones just months after birth. Lacking muscle tone, they never learn to sit up, develop heads too large to lift and eventually suffer uncontrollable seizures. There is no cure.

22 Feb 2018

UNIST researchers introduce new biosensing contact lens for diabetics

A team of researchers, affiliated with UNIST has recently introduced a new biosensing contact lens capable of detecting glucose levels in patients with diabetes.

22 Feb 2018

Scientists reveal development of improved medicine to fight addiction

Drug addiction continues to plague vast numbers of people across the world, destroying and ending lives, while attempts to develop more effective pharmaceutical addiction treatments continue.

21 Feb 2018

Research findings could help develop new drugs to prevent, treat dry eye disease

With computers, smartphones and contact lenses now essential to modern life, many -- one out of every 10 Japanese people -- suffer dry eye disease.

20 Feb 2018

Scientists explore connection between bad sleep habits and stiff blood vessels

What do bad sleep habits and stiff blood vessels have in common? Nothing good, say scientists exploring what appears to be a direct connection between a circadian clock that isn't working as it should and an enzyme that promotes inflammation working overtime.

20 Feb 2018

Researchers discover that activation of specific enzyme may help suppress tumor metastasis

To stop the spread of cancer, cancer cells must die. Unfortunately, many types of cancer cells seem to use innate mechanisms that block cancer cell death, therefore allowing the cancer to metastasize.

19 Feb 2018

Stanford researchers explore how enzyme changes and becomes antibiotic-resistant

Enzymes are proteins that speed up or catalyze a reaction in living organisms. Bacteria can produce enzymes that make them resistant to antibiotics.

19 Feb 2018

Deletion of specific enzyme leads to improvement in memory and cognitive functions

A new study in mice has made a possible breakthrough in Alzheimer’s research. The team of researchers at the Cleveland Clinic has noted that deleting a single enzyme can reverse the deposition of harmful plaques in the brains of patients with Alzheimer’s disease. This could improve cognitive functions as demonstrated in lab mice. The study appeared this week in the latest issue of the Journal of Experimental Medicine.

17 Feb 2018

Resolving Interfacial Protein Dynamics by STReM

STReM stands for Super Time-Resolved Microscopy, and as STORM, PALM, and other methods are designed to improve spatial resolution of optical microscopy, we desire to improve the time resolution. STReM makes use of point spread function engineering to encode fast events into each camera frame.

From Pittcon 16 Feb 2018

Gene editing tool used to detect cancer

Researchers have developed a DNA detection system that can detect the presence of bacterial and viral DNA, which could be a valuable diagnostic tool for a range of disorders.

16 Feb 2018

Potential new principle for treatment of multiple forms of cancer

A study published in Science Translational Medicine shows that small molecules that specifically inhibit an important selenium-containing enzyme may be useful in combating cancer. When researchers at Karolinska Institutet treated cancer in mice using these molecules, they observed rapid tumoricidal effects.

15 Feb 2018

CAR-T therapy saves life of cancer researcher

About a dozen years ago, Dr. Woodring Wright, a UT Southwestern Professor of Cell Biology, sneezed. It broke one of his vertebrae, the interlocking bones that make up the spinal column.

14 Feb 2018

Researchers uncover new details about function of enigmatic protein

In a recent study, a research group at MedUni Vienna has published further details about the function of an enigmatic protein. The biological necessity of this protein, which can chemically alter certain building blocks of the genetic information, has been debated for quite a while.

14 Feb 2018

Mice study raises hope to successfully treat Alzheimer's disease

A team of researchers from the Cleveland Clinic Lerner Research Institute have found that gradually depleting an enzyme called BACE1 completely reverses the formation of amyloid plaques in the brains of mice with Alzheimer's disease, thereby improving the animals' cognitive function.

14 Feb 2018

New review explores whether oral nutraceuticals benefit skin appearance

A review of published research conducted by nutrition scientists at the British Nutrition Foundation reveals a very limited evidence base to support some of the ingredients used in popular, and often costly, orally consumed beauty supplements, that promise ‘youthful’, ‘firm’ and ‘glowing’ skin.

14 Feb 2018