Pancreatic Cancer News and Research

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Pancreatic cancer is the fourth leading cause of all cancer deaths in the United States and the third leading cause of cancer deaths in individuals ages 40 to 60. Approximately 37,000 Americans are diagnosed with pancreatic cancer each year, and, each year, approximately the same number die from it. Often, pancreatic cancer is found too late for surgical intervention, and chemotherapy and radiation treatments have little effect.

Odor-based test could serve as a non-invasive approach to screen for harder-to-detect cancers

An odor-based test that sniffs out vapors emanating from blood samples was able to distinguish between benign and pancreatic and ovarian cancer cells with up to 95 percent accuracy, according to a new study from researchers at the University of Pennsylvania and Penn's Perelman School of Medicine.

1 Jun 2021

Researchers are developing first prognostic, therapeutic epigenetic biomarker for pancreatic cancer patients

By 2030, pancreatic ductal adenocarcinoma (PDAC), the most lethal form of pancreatic cancer, is projected to become the second leading cause of cancer-related deaths in the United States.

24 May 2021

UNSW researchers find novel way to attack the 'fortress' surrounding pancreatic tumors

Tackling the scar tissue that shields pancreatic tumors from effective drug access is a promising advance in a notoriously hard-to-treat cancer.

17 May 2021

Groundbreaking study optimizes patient's own immune system to fight tumors

A groundbreaking study led by engineering and medical researchers at the University of Minnesota Twin Cities shows how engineered immune cells used in new cancer therapies can overcome physical barriers to allow a patient's own immune system to fight tumors.

14 May 2021

Minorities substantially underrepresented in pancreatic cancer clinical trials

Despite the fact that certain racial and ethnic minorities get pancreatic cancer more often, are diagnosed at a younger age and die sooner, clinical trials fail to include representative proportions of non-White patients at every phase of study, according to research that was selected for presentation at Digestive Disease Week 2021.

14 May 2021

New study finds a stark decrease in the number of abdominal surgeries among older adults

Many have assumed that the rates of major abdominal surgeries in adults over 65 is increasing over time as the U.S. population ages and as new technology renders surgical procedures safer for older adults.

10 May 2021

Targeted therapies could exploit unique metabolic features of pancreatic cancer cells

Probing the unique biology of human pancreatic cancer cells in a laboratory has yielded unexpected insights of a weakness that can be used against the cells to kill them.

7 May 2021

Researchers develop new technology to reduce high error rates in gene sequencing

Next-generation gene sequencing (NGS) technologies --in which millions of DNA molecules are simultaneously but individually analyzed-- theoretically provides researchers and clinicians the ability to noninvasively identify mutations in the blood stream.

4 May 2021

Pancreatic cancer cells de-differentiate to spawn highly aggressive tumors, study shows

A Ludwig Cancer Research study has identified a previously unrecognized mechanism by which cancer cells of a relatively benign subtype of pancreatic tumors methodically revert-or "de-differentiate"-to a progenitor, or immature, state of cellular development to spawn highly aggressive tumors that are capable of metastasis to the liver and lymph nodes.

29 Apr 2021

Researchers develop first 3D organoid models of the pancreas from human stem cells

This year, more than 60,000 adults in the United States will be diagnosed with pancreatic cancer and, statistically, as few as 10 percent will survive five years after diagnosis, according to the American Cancer Society.

28 Apr 2021

Study sheds new light on the ability of pancreatic cancer cells to metastasize

With an overall survival rate of 9% for those diagnosed, pancreatic cancer remains exceedingly difficult to treat. However, the patient's primary tumor typically isn't what leads to death - it is the cancer's ability to evade detection and metastasize to other organs.

19 Apr 2021

COVID-19 deadlier than cars for over 40s, study finds

The study, which appeared on the pre-print server medRxiv, presented mortality rates and case-fatality rates for COVID-19 compared with other historic leading causes of death in the United States.

15 Apr 2021

Experts to discuss advanced cancer cell and gene therapies at Summit 2021

April 29 marks a pivotal moment in cancer research when the world's brightest minds come together to discuss how to translate the success of CAR T-cell therapies for blood cancers into successful cell and gene therapies for the most complex and deadly solid tumor cancers.

15 Apr 2021

Breast cancer survivors with excess body weight at increased risk of developing second cancer

Breast cancer survivors who are overweight have a statistically significant increased risk of developing second primary cancers, according to results from a study conducted by Kaiser Permanente researchers and published in the Journal of the National Cancer Institute.

12 Apr 2021

CD40 drug before surgery can benefit patients with early-stage pancreatic cancer

Giving early-stage pancreatic cancer patients a CD40 immune-stimulating drug helped jumpstart a T cell attack to the notoriously stubborn tumor microenvironment before surgery and other treatments, according to a new study from researchers in the Abramson Cancer Center (ACC) at the University of Pennsylvania.

12 Apr 2021

Mutant KRAS and P53 promote growth and metastasis of pancreatic cancer

Researchers at The University of Texas MD Anderson Cancer Center have discovered that mutant KRAS and p53, the most frequently mutated genes in pancreatic cancer, interact through the CREB1 protein to promote metastasis and tumor growth.

12 Apr 2021

Inhibition of NLRP3 complex can reduce inflammation in melanoma patients

Cancer doctors may soon have a new tool for treating melanoma and other types of cancer, thanks to work being done by researchers at the University of Colorado Cancer Center.

8 Apr 2021

The Dream Team opens clinical trial to find better treatment options for pancreatic cancer

A new team of pioneering pancreatic cancer researchers has been formed to predict which treatments might work best for individual pancreatic cancer patients based on the molecular traits of tumors.

30 Mar 2021

Surgery is viable in more pancreatic cancer cases than commonly thought, study shows

Patients with stage II pancreatic cancer who are treated with chemotherapy followed by resection (an operation that removes the cancerous part of the organ, structure or tissue) live nearly twice as long as patients who receive only chemotherapy, according to a new Journal of the American College of Surgeons study published online in advance of print.

26 Mar 2021

UCLA researchers receive NIH grants to identify new ways to treat pancreatic cancer

A team of researchers from the UCLA Jonsson Comprehensive Cancer Center has been awarded two research grants totaling $6 million from the National Institutes of Health to identify new ways to treat pancreatic cancer.

25 Mar 2021

Pancreatic Cancer News and Research

Further Reading

Odor-based test could serve as a non-invasive approach to screen for harder-to-detect cancers

Researchers are developing first prognostic, therapeutic epigenetic biomarker for pancreatic cancer patients

UNSW researchers find novel way to attack the 'fortress' surrounding pancreatic tumors

Groundbreaking study optimizes patient's own immune system to fight tumors

Minorities substantially underrepresented in pancreatic cancer clinical trials

New study finds a stark decrease in the number of abdominal surgeries among older adults

Targeted therapies could exploit unique metabolic features of pancreatic cancer cells

Researchers develop new technology to reduce high error rates in gene sequencing

Pancreatic cancer cells de-differentiate to spawn highly aggressive tumors, study shows

Researchers develop first 3D organoid models of the pancreas from human stem cells

Study sheds new light on the ability of pancreatic cancer cells to metastasize

COVID-19 deadlier than cars for over 40s, study finds

Experts to discuss advanced cancer cell and gene therapies at Summit 2021

Breast cancer survivors with excess body weight at increased risk of developing second cancer

CD40 drug before surgery can benefit patients with early-stage pancreatic cancer

Mutant KRAS and P53 promote growth and metastasis of pancreatic cancer

Inhibition of NLRP3 complex can reduce inflammation in melanoma patients

The Dream Team opens clinical trial to find better treatment options for pancreatic cancer

Surgery is viable in more pancreatic cancer cases than commonly thought, study shows

UCLA researchers receive NIH grants to identify new ways to treat pancreatic cancer

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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