Therapeutics News and Research

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MILabs completes installation of latest VECTor5CT system at University of Copenhagen

MILabs announced today that it has successfully completed the installation of its top-of-the-line multimodality PET-SPECT-UHR CT in the laboratory of Prof. Maiken Nedergaard, M.D, D.M.Sci. – Center for Translational Neuroscience, Division of Glial Disease and Therapeutics.

6 Feb 2018

Researchers pave way toward new therapeutic approach for gonorrhea

Researchers are paving the way toward a new therapeutic approach for gonorrhea by shedding light on the mechanism behind important proteins on the Neisseria gonorrhoeae bacteria's outer membrane.

6 Feb 2018

Discovery opens new doors to developing vaccines for preventing staph skin infections

After years of investigation, researchers at Johns Hopkins, the University of California, Davis, and the National Institute of Allergy and Infectious Diseases have discovered how the immune system might protect a person from recurrent bacterial skin infections caused by Staphylococcus aureus (staph).

6 Feb 2018

Novel grape-derived compounds could be developed as therapeutic agents for treatment of depression

In a study to be published online February 2 in Nature Communications, scientists from the Icahn School of Medicine at Mount Sinai describe an extensive analysis of novel grape-derived compounds, dihydrocaffeic acid (DHCA) and malvidin-3'-O-glucoside (Mal-gluc),which might be developed as therapeutic agents for the treatment of depression.

2 Feb 2018

New modular platform offers robust biological approach that targets endless number of diseases

The biological complexity of cancer and other diseases demands a more formidable arsenal of therapies than currently available. Most therapeutic approaches ignore the dynamic molecular network of genes, targeting instead only very few selected disease-related genes.

1 Feb 2018

New clinical practice guideline for using CYP2D6 genotype to guide tamoxifen therapy

An international group of clinicians and scientists representing the Clinical Pharmacogenetics Implementation Consortium published the first-ever clinical practice guideline for using CYP2D6 genotype to guide tamoxifen therapy in Clinical Pharmacology and Therapeutics.

1 Feb 2018

Two bacterial species collaborate to drive development of colon cancers

Patients with an inherited form of colon cancer harbor two bacterial species that collaborate to encourage development of the disease, and the same species have been found in people who develop a sporadic form of colon cancer, a study led by a Johns Hopkins Bloomberg~Kimmel Institute for Cancer Immunotherapy research team finds.

1 Feb 2018

Scientists identify new approach to enhance bone healing

When a patient breaks a bone, there's a possibility the fracture won't heal properly or quickly -- even with the aid of pins, plates or a cast.

1 Feb 2018

UTA receives new grant to develop manufacturing process for REHEAL glove

The University of Texas at Arlington has received a new $227,000 grant funded through the federal government's Medical Technology Enterprise Consortium to develop the manufacturing process for the REHEAL glove, a bioengineered healing glove that delivers medicine to injured hands to speed up healing.

31 Jan 2018

Stealth gene shuttles open up new avenues to treat aggressive cancers

Viruses have their own genetic material and can infect human cells in a very specific manner. They will then reproduce as directed by their own genes but using the resources of the host cell.

31 Jan 2018

Computational approach can help identify chemoresistant potential targets in cancer stem cells

In cancer, one of the most important features is the methylation of deoxycytosine to form 5-methylcytosine (5mC). DNA methylation is a process by which methyl groups (structural units of organic compounds consisting of three hydrogen atoms bonded to a carbon atom) are added to the DNA molecule.

30 Jan 2018

Altered flu virus could help combat pancreatic cancer, study finds

Researchers at Queen Mary University of London have developed a mechanism by which an altered or modified flu virus inhibit the growth of pancreatic cancer cells.

29 Jan 2018

Researchers discover new source of botulinum neurotoxin

A new source of the botulinum neurotoxin was discovered by Canadian and American scientists in a strain of animal gut bacteria known as Enterococcus faecium.

27 Jan 2018

Study shows link between epilepsy and structural differences in grey matter

Research carried out by researchers at RCSI in partnership with UCL and the Keck School of Medicine of USC has revealed an association between epilepsy and the thickness and volume differences in the grey matter of several brain regions. The research is published today in Brain.

24 Jan 2018

Chinese researchers develop multifunctional vehicle to transport gene therapeutics

Gene editing is one of the hottest topics in cancer research. A Chinese research team has now developed a gold-nanoparticle-based multifunctional vehicle to transport the "gene scissors" to the tumor cell genome.

22 Jan 2018

World’s first vaccine relieves grass pollen allergy symptoms by at least 25%, study shows

Around 400 million people world-wide suffer in some form or other from a grass pollen allergy (rhinitis) - with the usual symptoms such as a runny nose, cough and severe breathing problems.

18 Jan 2018

Penn scientists identify new therapeutic target for treatment of melanoma

Researchers in the Perelman School of Medicine at the University of Pennsylvania have identified a new therapeutic target for the treatment of melanoma.

16 Jan 2018

Researchers use immune-mimicking biomaterial scaffolds to fast track T cell therapies

Immunologists and oncologists are harnessing the body's immune system to fight cancers and other diseases with adoptive cell transfer techniques. In a normal immune response, a type of white blood cell known as T cells are instructed by another kind of immune cell called an antigen-presenting cell (APC) to expand their numbers and stay alive.

15 Jan 2018

Exposure to estrogen-mimicking compounds may reverse effects of breast cancer treatment

Scientists from The Scripps Research Institute have discovered that two estrogen-mimicking compounds found in many foods appear to potently reverse the effects of palbociclib/letrozole, a popular drug combination for treating breast cancer.

12 Jan 2018

Novel antifungal shows promise to stave off drug-resistant superbugs

Microscopic yeast have been wreaking havoc in hospitals around the world- creeping into catheters, ventilator tubes, and IV lines- and causing deadly invasive infection.

11 Jan 2018

Therapeutics News and Research

MILabs completes installation of latest VECTor5CT system at University of Copenhagen

Researchers pave way toward new therapeutic approach for gonorrhea

Discovery opens new doors to developing vaccines for preventing staph skin infections

Novel grape-derived compounds could be developed as therapeutic agents for treatment of depression

New modular platform offers robust biological approach that targets endless number of diseases

New clinical practice guideline for using CYP2D6 genotype to guide tamoxifen therapy

Two bacterial species collaborate to drive development of colon cancers

Scientists identify new approach to enhance bone healing

UTA receives new grant to develop manufacturing process for REHEAL glove

Stealth gene shuttles open up new avenues to treat aggressive cancers

Computational approach can help identify chemoresistant potential targets in cancer stem cells

Altered flu virus could help combat pancreatic cancer, study finds

Researchers discover new source of botulinum neurotoxin

Study shows link between epilepsy and structural differences in grey matter

Chinese researchers develop multifunctional vehicle to transport gene therapeutics

World’s first vaccine relieves grass pollen allergy symptoms by at least 25%, study shows

Penn scientists identify new therapeutic target for treatment of melanoma

Researchers use immune-mimicking biomaterial scaffolds to fast track T cell therapies

Exposure to estrogen-mimicking compounds may reverse effects of breast cancer treatment

Novel antifungal shows promise to stave off drug-resistant superbugs

Event guide: The Non-Opioid Pain Therapeutics Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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