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Mechanistic insight into how receptor location is the key for psychedelic drug effects

Location, location, location is the key for psychedelic drugs that could treat mental illness by rapidly rebuilding connections between nerve cells.

17 Feb 2023

LLNL licensee and collaborators develop novel medicines to combat autoimmune diseases

People afflicted with autoimmune diseases may someday receive help through treatments now under development by a Lawrence Livermore National Laboratory licensee and its' collaborations with two major pharmaceutical companies.

17 Feb 2023

The prevalence of spike-protein antibodies following at least 3 COVID-19 vaccine doses in immunocompromised individuals

Researchers determined the prevalence of antibodies against the SARS-CoV-2 spike glycoprotein following three or more doses of COVID-19 vaccines among immunocompromised individuals.

17 Feb 2023

Mark Cuban has been taking on the drug industry. But which one?

When billionaire Mark Cuban announced his attack on the pharmaceutical industry and its high-priced drugs in January 2021, it was met with cheers.

17 Feb 2023

After staying away during pandemic, doctors return to lobby Congress

Dr. Timothy McAvoy, an internist from Waukesha, Wisconsin, held his infant granddaughter Tuesday while standing in the Longworth House Office Building, waiting to talk to a congressional aide about increasing Medicare pay for doctors.

17 Feb 2023

Pharma companies could provide new, affordable drugs by refocusing their spending, experts say

High drug prices are not justified by industry's spending on research and development (R&D), argue experts in The BMJ today.

16 Feb 2023

CHLA researchers receive funding to support studies into diffuse intrinsic pontine glioma

Researchers at Children's Hospital Los Angeles have received a nearly $1 million K08 grant from the National Institutes of Health (NIH) - as well as funding from the U.S. Department of Defense - to support studies into diffuse intrinsic pontine glioma (DIPG), a childhood brain tumor with a 0% survival rate.

16 Feb 2023

Neuroscientists discover new way to disrupt chronic inflammation responsible for multiple sclerosis

UVA Health neuroscientists have discovered a potential way to disrupt the chronic inflammation responsible for multiple sclerosis.

16 Feb 2023

Study provides a rare view of real-world use of off-label drugs prescribed for Type 1 diabetes

Two classes of drugs prescribed off-label for some patients with Type 1 diabetes can provide significant benefits but also come with health concerns, according to a study by UT Southwestern Medical Center researchers.

16 Feb 2023

Penn engineers address the longstanding gap in reproductive health care with targeted RNA therapy

Pre-eclampsia is a leading cause of stillbirths and prematurity worldwide, occurring in 3 – 8 % of pregnancies. A disorder characterized by high maternal blood pressure, it results from insufficient vasodilation in the placenta, restricting blood flow from the mother to the fetus.

16 Feb 2023

A call to action proposed for health providers to ensure widest distribution, easy availability of naloxone

In 2021, 100,306 Americans died from drug overdoses – a 28.5 percent increase from the prior year – with 75,673 attributed to opioids.

16 Feb 2023

Repurposing or improving drugs for spinocerebellar ataxia type 5

A team of researchers has developed a new method to screen FDA-approved drugs to determine if they could be repurposed or improved to help patients with a rare, debilitating disease of the nervous system.

16 Feb 2023

Nirmatrelvir–ritonavir found to lower COVID-19 severity outcomes

Researchers evaluated the effectiveness of nirmatrelvir–ritonavir in preventing coronavirus disease 2019 (COVID-19) severity outcomes during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant predominance.

16 Feb 2023

Cohort study examines the incidence of SARS-CoV-2 rebound in patients on oral antivirals

Researchers performed a retrospective population-wide cohort study using anonymized data in Hong Kong, China, between February 26 and July 3, 2022.

16 Feb 2023

Death of a zoo hippopotamus underscores the species’ susceptibility to SARS-CoV-2

A recent study investigated the death of a hippopotamus at a zoo in Hanoi, Vietnam.

16 Feb 2023

Brain cells may age faster in people with cocaine use disorder

A new study finds evidence from the DNA methylome that the biological age – different from the chronological age – of cells in Brodmann Area 9 of the prefrontal cortex might be greater in people with cocaine use disorder.

16 Feb 2023

UIC scientists find new way to better target cellular proteins

By studying how enzymes move from one membrane compartment to another inside a cell, scientists at the University of Illinois Chicago have figured out a way to better target cellular proteins, which play a role in many diseases.

15 Feb 2023

Researchers gain deeper understanding of risk factors associated with low birthweights

Multiple births, a short interval between pregnancies and mothers with a maternal physical or mental health condition are more at risk of having a low birth rate baby according to Swansea University researchers.

15 Feb 2023

Electrochemical method helps to continuously witness and analyze details of protein folding

Scientists are not yet clear on how the tau protein changes from a benign protein essential for normal function in our brains into the toxic neurofibrillary tangles that are a signature of Alzheimer's and other neurodegenerative diseases.

15 Feb 2023

Rapid clinical test predicts which people with neck pain may benefit from epidural steroid injections

Researchers from Johns Hopkins Medicine and several other institutions say they have developed a quick clinical test that predicts which people with neck pain are more likely to benefit from epidural steroid injections, which deliver drugs directly around the spinal nerves to stop nerve inflammation and reduce pain.

15 Feb 2023

Drugs News and Research

Mechanistic insight into how receptor location is the key for psychedelic drug effects

LLNL licensee and collaborators develop novel medicines to combat autoimmune diseases

The prevalence of spike-protein antibodies following at least 3 COVID-19 vaccine doses in immunocompromised individuals

Mark Cuban has been taking on the drug industry. But which one?

After staying away during pandemic, doctors return to lobby Congress

Pharma companies could provide new, affordable drugs by refocusing their spending, experts say

CHLA researchers receive funding to support studies into diffuse intrinsic pontine glioma

Neuroscientists discover new way to disrupt chronic inflammation responsible for multiple sclerosis

Study provides a rare view of real-world use of off-label drugs prescribed for Type 1 diabetes

Penn engineers address the longstanding gap in reproductive health care with targeted RNA therapy

A call to action proposed for health providers to ensure widest distribution, easy availability of naloxone

Repurposing or improving drugs for spinocerebellar ataxia type 5

Nirmatrelvir–ritonavir found to lower COVID-19 severity outcomes

Cohort study examines the incidence of SARS-CoV-2 rebound in patients on oral antivirals

Death of a zoo hippopotamus underscores the species’ susceptibility to SARS-CoV-2

Brain cells may age faster in people with cocaine use disorder

UIC scientists find new way to better target cellular proteins

Researchers gain deeper understanding of risk factors associated with low birthweights

Electrochemical method helps to continuously witness and analyze details of protein folding

Rapid clinical test predicts which people with neck pain may benefit from epidural steroid injections

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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