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Children's Hospital Colorado announces participation in pivotal trial of synthetic restorative pulmonary valve

Children's Hospital Colorado today announced it has joined the Xplore2/Pivotal trial, and is actively enrolling patients for the first-ever pivotal trial of a synthetic restorative pulmonary valve.

9 Aug 2021

Flavonoid-based inhibitors targeting SARS-CoV 3CL protease for the treatment of SARS-CoV-2 infection

A new study has explored a series of potential flavonoid inhibitors targeting 3CL protease of SARS-CoV.

9 Aug 2021

New study receives $33 million PCORI funding to compare anesthetic medications

More than 50,000 surgical patients undergo general anesthesia every day in the United States, but clinicians and scientists lack evidence indicating which types of anesthesia drugs result in the best outcomes for patients.

9 Aug 2021

Quanterix Simoa® Technology Powers Breakthrough Alzheimer’s Disease Research Presented by Eli Lilly and Company at Alzheimer’s Association International Conference (AAIC) 2021

Ultra-sensitive Simoa® HD-X technology powers new findings that detect rapid reduction of plasma P-tau217 from donanemab, Lilly’s investigational antibody therapy for Alzheimer's disease at 12 weeks

From Quanterix 9 Aug 2021

Study of antibody responses to COVID-19 mRNA vaccine in convalescent individuals

In addition to clinical trials conducted to determine the safety and efficacy of the mRNA vaccines, additional studies began describing the serological response to the vaccines under "real-world" conditions, especially with the onset of the SARS-CoV-2 variants and case reports of vaccine escape.

9 Aug 2021

New compound inspired by tapeworm drugs shows two-pronged effectiveness against COVID-19

A group of medications long prescribed to treat tapeworm has inspired a compound that shows two-pronged effectiveness against COVID-19 in laboratory studies, according to a new publication appearing online in the journal ACS Infectious Disease.

9 Aug 2021

Scientists identify calpeptin as potential inhibitor of SARS-CoV-2

A team of US-based scientists has recently conducted a robust high-throughput screening to identify potential entry inhibitors of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The screening identifies calpeptin as a potent and highly specific inhibitor of SARS-CoV-2 and its variants. The study is currently available on the bioRxiv* preprint server.

9 Aug 2021

Cetylpyridinium chloride-containing mouthwashes shown to inhibit SARS-CoV-2 in oral cavity

A team of international scientists has recently demonstrated the usefulness of cetylpyridinium chloride-containing mouthwashes in inhibiting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and reducing the risk of viral transmission. The study is currently available on the bioRxiv* preprint server.

9 Aug 2021

Surfactant-coated nanoparticle applications in nanomedicine and food

A group of researchers critically review the use of surfactant-coated nanoparticles in the fields of nanomedicine and food nanotechnology.

8 Aug 2021

Oral drug found to be effective, safe for treating anemia in patients with chronic kidney disease

Pooled results from recent clinical trials indicate that an oral drug called roxadustat is an effective treatment for anemia in patients with chronic kidney disease.

6 Aug 2021

Online training leverages the influence of religion to prevent intimate partner violence

Domestic violence remains a serious and widespread problem in the U.S., particularly for women from racial or ethnic minorities, who experience higher rates of abuse than the national average.

6 Aug 2021

Topical cream shows signs of clinical efficacy in patients with basal cell carcinoma

Remetinostat, a topical cream and first-in-class inhibitor of histone deacetylation, showed signs of clinical efficacy in patients with basal cell carcinoma.

6 Aug 2021

Aducanumab approval for Alzheimer's may provide a proof of concept that can be rapidly improved upon

The recent US Food and Drug Administration (FDA) approval of aducanumab – which has the potential to treat Alzheimer's disease – may provide a proof of concept that can be rapidly improved upon, writes Dennis Selkoe in this Perspective.

6 Aug 2021

Study reports on COVID-19 vaccine-related adverse events in young Japanese population

A new study from Japan, released as a medRxiv* preprint, describes the adverse effects associated with the vaccine. Such data is crucial in delineating the safety and efficacy of this intervention in various age groups.

6 Aug 2021

Double vaccinated three times less likely to test positive for COVID-19 than unvaccinated, says study

In new research, scientists at Imperial College London report that double vaccinated individuals could be three times less likely than unvaccinated people to test positive for SARS-CoV-2 infection.

6 Aug 2021

Expert highlights the progress and challenges in developing blood tests for Alzheimer's disease

Given the progress in therapeutics for Alzheimer's disease (AD), including the recent approval of aducanumab – the first anti-amyloid immunotherapy approved by the FDA for the disease – there is a need for simple blood tests that could be used to ensure accurate diagnosis and assess therapeutic progress.

6 Aug 2021

Efficacy News and Research

Children's Hospital Colorado announces participation in pivotal trial of synthetic restorative pulmonary valve

Flavonoid-based inhibitors targeting SARS-CoV 3CL protease for the treatment of SARS-CoV-2 infection

New study receives $33 million PCORI funding to compare anesthetic medications

Quanterix Simoa® Technology Powers Breakthrough Alzheimer’s Disease Research Presented by Eli Lilly and Company at Alzheimer’s Association International Conference (AAIC) 2021

Study of antibody responses to COVID-19 mRNA vaccine in convalescent individuals

New compound inspired by tapeworm drugs shows two-pronged effectiveness against COVID-19

Scientists identify calpeptin as potential inhibitor of SARS-CoV-2

Cetylpyridinium chloride-containing mouthwashes shown to inhibit SARS-CoV-2 in oral cavity

Surfactant-coated nanoparticle applications in nanomedicine and food

Oral drug found to be effective, safe for treating anemia in patients with chronic kidney disease

Online training leverages the influence of religion to prevent intimate partner violence

Topical cream shows signs of clinical efficacy in patients with basal cell carcinoma

Aducanumab approval for Alzheimer's may provide a proof of concept that can be rapidly improved upon

Study reports on COVID-19 vaccine-related adverse events in young Japanese population

Double vaccinated three times less likely to test positive for COVID-19 than unvaccinated, says study

Expert highlights the progress and challenges in developing blood tests for Alzheimer's disease

Magnetic nanoparticles could enhance the efficacy of cancer immunotherapy

Nightlife industry joins national effort to drive COVID-19 vaccine uptake among young people

Combination therapy improves outcomes for relapsed chronic lymphocytic leukemia

Research suggests potential new treatment strategy for phenylketonuria

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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