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NIH initiates a clinical trial evaluating an investigational antiviral for treatment of COVID-19

The National Institutes of Health has initiated a multi-site clinical trial evaluating an investigational antiviral for the treatment of COVID-19.

15 Feb 2023

As opioids mixed with animal tranquilizers arrive in Kensington, so do alarming health challenges

Many people living on the streets in Philadelphia's Kensington neighborhood — the largest open-air drug market on the East Coast — are in full-blown addiction, openly snorting, smoking, or injecting illicit drugs, hunched over crates or on stoops. Syringes litter sidewalks, and the stench of urine fouls the air.

15 Feb 2023

Cocaine use disorder leads to changes in the 'methylome' of a brain region

Scientists tend to view substance addiction as primarily a disease of the brain. When we enjoy sex, food, music, or hobbies, regions of our brain within the reward pathway are flooded with pleasure-inducing dopamine.

14 Feb 2023

Enhanced prediction of prostate cancer recurrence using machine learning model

Predicting the course of prostate cancer is challenging because only a fraction of prostate cancer patients experience recurrence after radical prostatectomy or radiation therapy.

14 Feb 2023

The association between cannabis use and sleep complaints in University students

Researchers examined the associations between cannabis use and sleep disturbances.

14 Feb 2023

Your money or your life: Patient on $50,000-a-week cancer drug fears leaving behind huge medical debt

After several rounds of treatment for a rare eye cancer — weekly drug infusions that could cost nearly $50,000 each — Paul Davis learned Medicare had abruptly stopped paying the bills.

14 Feb 2023

Drug treatment in adulthood can counteract the behavioral abnormalities typical of autism

The behavioral disorders observed in autism are associated with a multitude of genetic alterations. Scientists from the Hector Institute for Translational Brain Research (HITBR) have now found another molecular cause for this condition.

14 Feb 2023

High doses of cannabidiol may increase the effects of THC in edible cannabis products

Contrary to some common claims, a study led by Johns Hopkins Medicine researchers found that relatively high doses of cannabidiol (CBD) may increase the adverse effects of delta-9-tetrahydrocannabinol (THC), the main active ingredient in cannabis that can cause a mood alteration or a "high" sensation.

13 Feb 2023

Exploring two small molecules for the disintegration of alpha-synuclein fibrils

In a recent study published in the Proceedings of the National Academy of Sciences, researchers assessed the capability of two small molecules of disintegrating alpha-synuclein fibrils.

13 Feb 2023

Two cardiovascular drugs may help improve outcomes for patients who experienced small vessel stroke

A study of two widely used cardiovascular medications — cilostazol and isosorbide mononitrate — in more than 350 patients confirmed the two medications were well-tolerated and safe for people who have experienced a stroke in a small blood vessel deep in the brain.

13 Feb 2023

Research details how the circadian and circannual cycles influence humans at the molecular level

The daily rotation of Earth and its yearly voyage around the Sun marks the natural rhythm of life on the planet.

13 Feb 2023

Scientists illuminate the mechanisms that prevent p53 activation from triggering cancer cell death

Cancer is a disease driven by gene mutations. These mutated genes in cancer fall into two major categories: tumor suppressors and oncogenes.

13 Feb 2023

Statewide analysis of deaths in Florida associated with cannabis use

In the United States, 49.6 million Americans ages 12 and older used cannabis or marijuana in 2020. More than 5.4 million Americans are medical cannabis patients.

10 Feb 2023

Five teams awarded funding from the Starr Cancer Consortium to advance cancer research

Five teams led by Weill Cornell Medicine scientists have been awarded funding from the Starr Cancer Consortium in its 16th annual grant competition.

10 Feb 2023

Mark Cuban's cost-plus drug pricing model offers significant savings to patients

A new drug company founded by entrepreneur Mark Cuban could save patients $1.29 billion a year based on 2020 Medicare Part D expenditures on just the nine most popular urological drugs, according to a study published in the Journal of Urology.

10 Feb 2023

Molecular switch regulates autophagy in plants

Autophagy, or "self-eating", is an essential cellular quality control mechanism that clears the cell of protein aggregates and damaged organelles. This mechanism is inactive under normal conditions and only triggered upon persistent cellular stress.

10 Feb 2023

New compound limits the replication of influenza viruses

Viruses use the molecular repertoire of the host cell to replicate. Researchers from the Cluster of Excellence ImmunoSensation2 at the University of Bonn, together with Japanese researchers, want to exploit this for the treatment of influenza.

9 Feb 2023

Scientists discover a protein in the lung that blocks SARS-CoV-2 infection

University of Sydney scientists have discovered a protein in the lung that blocks SARS-CoV-2 infection and forms a natural protective barrier in the human body.

9 Feb 2023

New formulation can provide up to six months of full protection against HIV

For people at high risk of contracting HIV, missing doses of their daily HIV prevention pills can have big consequences. In some cases, missing a pill can lead to lack of protection against the virus.

9 Feb 2023

A health-heavy State of the Union

Health care was a recurring theme throughout President Joe Biden's 2023 State of the Union address on Capitol Hill this week.

9 Feb 2023

Drugs News and Research

NIH initiates a clinical trial evaluating an investigational antiviral for treatment of COVID-19

As opioids mixed with animal tranquilizers arrive in Kensington, so do alarming health challenges

Cocaine use disorder leads to changes in the 'methylome' of a brain region

Enhanced prediction of prostate cancer recurrence using machine learning model

The association between cannabis use and sleep complaints in University students

Your money or your life: Patient on $50,000-a-week cancer drug fears leaving behind huge medical debt

Drug treatment in adulthood can counteract the behavioral abnormalities typical of autism

High doses of cannabidiol may increase the effects of THC in edible cannabis products

Exploring two small molecules for the disintegration of alpha-synuclein fibrils

Two cardiovascular drugs may help improve outcomes for patients who experienced small vessel stroke

Research details how the circadian and circannual cycles influence humans at the molecular level

Scientists illuminate the mechanisms that prevent p53 activation from triggering cancer cell death

Statewide analysis of deaths in Florida associated with cannabis use

Five teams awarded funding from the Starr Cancer Consortium to advance cancer research

Mark Cuban's cost-plus drug pricing model offers significant savings to patients

Molecular switch regulates autophagy in plants

New compound limits the replication of influenza viruses

Scientists discover a protein in the lung that blocks SARS-CoV-2 infection

New formulation can provide up to six months of full protection against HIV

A health-heavy State of the Union

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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