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Toothpaste ingredient could be employed as anti-malarial drug against drug-resistant parasites

An ingredient commonly found in toothpaste could be employed as an anti-malarial drug against strains of malaria parasite that have grown resistant to one of the currently-used drugs.

19 Jan 2018

Novel gene expression analysis technique can accurately and quickly measure RNA

A University of Illinois and Mayo collaboration has demonstrated a novel gene expression analysis technique that can accurately measure levels of RNA quickly and directly from a cancerous tissue sample while preserving the spatial information across the tissue --something that conventional methods cannot do.

18 Jan 2018

Genetic study identifies six new gene regions associated with type 1 diabetes in children

This article outlines a recent study which identified six novel gene regions in children who are at risk of type 1 diabetes.

17 Jan 2018

Scientists identify six new gene regions that may help treat type 1 diabetes

Six novel chromosomal regions identified by scientists leading a large, prospective study of children at risk for type 1 diabetes will enable the discovery of more genes that cause the disease and more targets for treating or even preventing it.

17 Jan 2018

EXD2 enzyme facilitates protein production in mitochondria

Researchers from the Genomic Instability and Cancer Laboratory at Institute for Research in Biomedicine (IRB Barcelona) have identified a key role for EXD2 in protein production in the mitochondria, the cellular organelles responsible for the majority of energy generation.

17 Jan 2018

Bacteria linked to periodontitis may play role in onset of cancer

The bacteria that cause periodontitis, a disease affecting the tissues surrounding the teeth, seems to play a part also in the onset of pancreatic cancer, say the researchers at the University of Helsinki and the Helsinki University Hospital, Finland, and the Karolinska Institutet, Sweden.

16 Jan 2018

FDA grants approval for first drug to treat inherited breast cancer

The U.S. Food and Drug Administration today expanded the approved use of Lynparza (olaparib tablets) to include the treatment of patients with certain types of breast cancer that have spread (metastasized) and whose tumors have a specific inherited (germline) genetic mutation, making it the first drug in its class (PARP inhibitor) approved to treat breast cancer, and it is the first time any drug has been approved to treat certain patients with metastatic breast cancer who have a "BRCA" gene mutation.

15 Jan 2018

Scientists discover new enzyme that could help in the battle against obesity

Scientists have discovered a new enzyme in adipose tissue that helps regulate inflammation. The discovery could help in the battle against obesity.

15 Jan 2018

Genetic analysis can enhance outcomes of depression treatment

The failure of drugs such as SSRIs, used to treat depression, can be a result of genetic variations in patients.

12 Jan 2018

Novel antifungal shows promise to stave off drug-resistant superbugs

Microscopic yeast have been wreaking havoc in hospitals around the world- creeping into catheters, ventilator tubes, and IV lines- and causing deadly invasive infection.

11 Jan 2018

Scientists develop genetically engineered probiotic that targets and kills cancer cells in the gut

A new study has identified a way to turn a humble cocktail of bacteria and vegetables into a targeted system that finds and kills colorectal cancer cells.

11 Jan 2018

Study identifies enzyme that regulates inflammation and metabolism in fat tissue

The human body has two primary kinds of fat--white fat, which stores excess calories and is associated with obesity, and brown fat, which burns calories in order to produce heat and has garnered interest as a potential means of combating obesity.

11 Jan 2018

New discovery could help treat breast cancer through precision medicine

University of Alberta researchers have discovered a mechanism that may make cancer cells more susceptible to treatment. The research team found that the protein RYBP prevents DNA repair in cancer cells, including breast cancer.

9 Jan 2018

Researchers discover why exercise is good and high blood pressure is bad for the heart

When the heart is put under stress during exercise, it is considered healthy. Yet stress due to high blood pressure is bad for the heart. Why? And is this always the case? Researchers of the German Centre for Cardiovascular Research and of Heidelberg University Hospital have obtained new findings which indicate that a previously undetected signal pathway causes or protects from heart failure - depending on the type of stress.

9 Jan 2018

Researchers develop drug that supports cellular traffic jam theory in ALS/FTD

Neurodegeneration in ALS/FTD may be caused by TDP-43 aggregation in the cytoplasm, causing cellular traffic jams. The trial drug can sequester TDP-43.

9 Jan 2018

New understanding of how molecules regulate enzyme could lead to potential cancer targets

New understandings of how molecules affect the activity of an enzyme could lead to potential targets for the treatment of cancers and neurodegenerative diseases.

5 Jan 2018

Bielefeld scientists discover cause of initially unclear symptoms

The sequencing of the human genome has made it possible: nowadays scientists can discover potential disorders for which there are no known patients.

5 Jan 2018

Why Should We Weigh Every Protein in the Human Body?

Our mission is to advance the measurement of human proteins with greater precision, to bring to the world the benefits of absolute molecular specificity when it comes to interrogating proteins at the molecular level.

From Pittcon 5 Jan 2018

Study reveals a loophole in treatment of chronic lymphocytic leukemia

A team of researchers in Italy and Austria has determined that a drug approved to treat chronic lymphocytic leukemia (CLL) may be less effective in a particular subset of patients.

4 Jan 2018

Study illustrates the role of alcohol in causing damage to DNA and increased cancer risk

A new study conducted by a group of researchers at MRC Laboratory of Molecular Biology, Cambridge revealed the significant role of alcohol in causing damage to DNA in stem cells and thereby increasing cancer risks. The study was funded by Cancer Research UK and the results were published in Nature.

4 Jan 2018