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Nanoparticles carrying CRISPR gene editing tools for genetic modifications

Researchers from MIT have now developed nanoparticles that could carry CRISPR genetic editing systems deep within the cells and perform their functions on the DNA. The paper was published in the November issue of Nature Biotechnology.

14 Nov 2017

UCR researchers develop transgenic mosquitoes to help reduce spread of infectious diseases

Researchers at the University of California, Riverside have developed transgenic mosquitoes that stably express the Cas9 enzyme in their germline. The addition of Cas9 will enable the use of the CRISPR gene editing tool to make efficient, targeted changes to the mosquitoes' DNA.

14 Nov 2017

Dresden researchers develop molecular smoke alert for key human cancer gene

If it burns in a house smoke detectors alert us hence protecting life. A molecular smoke alert has now been developed by Dresden researchers for the TP53 gene, the most important human cancer gene. The alert goes on if the TP53 gene is mutated in cells.

14 Nov 2017

Specific way of spelling out genetic code likely allows viruses to evade our cellular defenses

For millions of years, humans and viruses have engaged in a constant tug of war: as our cells evolve new ways to defend us from our viral enemies, these pathogens in turn acquire new traits to sidestep those defenses.

13 Nov 2017

Researchers shed light on link between cholera outbreaks affecting African and American continents

Researchers at the Institut Pasteur and the Wellcome Trust Sanger Institute, in collaboration with several other international institutions, recently published two studies tracing the history of cholera outbreaks in Africa, Latin America and the Caribbean from the last 60 years.

13 Nov 2017

Researchers identify 'strategies' used by bacteria to protect themselves from antibiotics

Antibiotic resistance happens when bacteria evolve mechanisms to withstand the drugs which are used to treat infections.

13 Nov 2017

Scientists identify new genes needed by Streptococcus pyogenes to grow in human saliva

Scientific and veterinary research charity, the Animal Health Trust, in partnership with world-leading scientists at the Houston Methodist Research Institute, have identified new genes linked to how, Streptococcus pyogenes, an important cause of human disease, survives in people.

13 Nov 2017

Advances in genetic and stem cell techniques help identify therapeutic targets for neurological disorders

Research released today highlights advances in the use of CRISPR-Cas9 and human induced pluripotent stem cell technologies to identify novel therapeutic targets for neurological disorders such as schizophrenia and addiction.

13 Nov 2017

Researchers show how rhythm of DNA replication can be manipulated to kill cancer cells

Human cells divide and create new cells throughout life. In this process, a steady – even rhythmic – supply of DNA building blocks is needed to create new DNA. Now researchers from the University of Copenhagen are the first to show exactly how human cells regulate this process so it does not fail and cause illness.

10 Nov 2017

Common genetic fusion event could help identify patients with low-risk prostate cancer

Establishing the way in which a genetic alteration called a TMPRSS2-ERG gene fusion forms in a prostate cancer, rather than the presence of the gene fusion itself, could help identify patients with prostate cancer with a low risk of spreading, which might determine the best course of treatment for the patient.

10 Nov 2017

Gene technology can be potential game-changer for agriculture

Consumers will soon be eating gene-edited foods that have added nutrients, potatoes that do not turn brown, and mushrooms with a longer shelf life, scientists at The University of Queensland predict.

10 Nov 2017

Researchers develop new method that can curb spread of superbugs

Researchers from ITMO University and Center of Physical and Chemical Medicine developed an algorithm capable of tracking the spread of antibiotic resistance genes in gut microbiota DNA and revealed additional evidence of resistance genes transfer between different bacterial species.

10 Nov 2017

Antiviral drug selectively targets the most aggressive viruses, research says

An antiviral drug that inhibits a virus' replication machinery selectively targets the most aggressive viruses, according to new research that looked at the infection of individual cells by a virus and the consequence of antiviral intervention.

9 Nov 2017

Scientists uncover previously unknown mechanism to combat influenza A virus

Just as flu season swings into full gear, researchers from the University of Colorado Boulder and University of Texas at Austin have uncovered a previously unknown mechanism by which the human immune system tries to battle the influenza A virus.

8 Nov 2017

Repositive joins with experts from the U.S. to support development of NIH Data Commons Pilot Phase

Repositive, the Cambridge-based UK start-up that launched the largest global genomic data portal for research, has joined forces with leading data experts from the US to support the development of the NIH Data Commons Pilot Phase, designed to transform the way public biomedical data is stored and analyzed.

8 Nov 2017

FDA approves first targeted cancer treatment based on basket study

The US Food and Drug Administration has announced that it has approved the drug vemurafenib for the treatment of patients with BRAF V600-mutant Erdheim-Chester disease (ECD).

7 Nov 2017

Research suggests asymptomatic infection as source of norovirus outbreaks in Indonesia

Norovirus, also referred to as the "winter vomiting bug", is the most common cause of acute gastroenteritis in humans. A Japanese research team has shown that norovirus is significantly present in the stools of healthy volunteers in Indonesia who are asymptomatically infected with the virus.

6 Nov 2017

Scientists identify eight new genes involved in epileptic encephalopathy

Approximately 30 per cent of patients with epilepsy do not respond to anti-epileptic drugs. In these cases, all neurologists can do is attempt to find the right combination of medication through trial and error.

6 Nov 2017

Environmental toxin exposure may disrupt function of circadian clock, research shows

Can environmental toxins disrupt circadian rhythms - the biological "clock" whose disturbance is linked to chronic inflammation and a host of human disorders? Research showing a link between circadian disruption and plankton that have adapted to road salt pollution puts the question squarely on the table.

3 Nov 2017

New study shows link between gut bacteria and age-related chronic inflammation

A new study shows for the first time that gut bacteria from old mice induce age-related chronic inflammation when transplanted into young mice.

3 Nov 2017

Genome News and Research

Nanoparticles carrying CRISPR gene editing tools for genetic modifications

UCR researchers develop transgenic mosquitoes to help reduce spread of infectious diseases

Dresden researchers develop molecular smoke alert for key human cancer gene

Specific way of spelling out genetic code likely allows viruses to evade our cellular defenses

Researchers shed light on link between cholera outbreaks affecting African and American continents

Researchers identify 'strategies' used by bacteria to protect themselves from antibiotics

Scientists identify new genes needed by Streptococcus pyogenes to grow in human saliva

Advances in genetic and stem cell techniques help identify therapeutic targets for neurological disorders

Researchers show how rhythm of DNA replication can be manipulated to kill cancer cells

Common genetic fusion event could help identify patients with low-risk prostate cancer

Gene technology can be potential game-changer for agriculture

Researchers develop new method that can curb spread of superbugs

Antiviral drug selectively targets the most aggressive viruses, research says

Scientists uncover previously unknown mechanism to combat influenza A virus

Repositive joins with experts from the U.S. to support development of NIH Data Commons Pilot Phase

FDA approves first targeted cancer treatment based on basket study

Research suggests asymptomatic infection as source of norovirus outbreaks in Indonesia

Scientists identify eight new genes involved in epileptic encephalopathy

Environmental toxin exposure may disrupt function of circadian clock, research shows

New study shows link between gut bacteria and age-related chronic inflammation

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