Preclinical News and Research

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GUMC licenses worldwide rights of 'theranostic' to BioMetrx

Georgetown University Medical Center (GUMC) has licensed worldwide rights of a potential novel cancer therapy and diagnostic, or "theranostic," to BioMetrx, LLC. The agent was invented by two Georgetown researchers.

25 Jan 2012

Sofie to receive U.S. patent for novel PET probes

Sofie Biosciences, Inc., offering a comprehensive range of products from pre-clinical PET imaging systems to new PET molecular imaging probes to better understand human disease, has been told that a U.S. Patent (8,101,740) will be granted by the United States Patent Office on technology that has been exclusively licensed to Sofie. The patent covers a family of novel PET probes, known as [18F]FAC.

25 Jan 2012

Aphios receives NIH's Phase II SBIR grant to develop APH-0703 for AD

Aphios Corporation has received a Phase II SBIR grant from the National Institutes of Health (NIH) amounting to $2.4 million over two years. The National Institute on Aging (NIA), part of the NIH, awarded the grant to the Aphios Corporation to develop an "Alzheimer's Disease Therapeutic."

24 Jan 2012

Genoscience, BioLineRx to develop and commercialize BL-8020 for HCV

BioLineRx, a biopharmaceutical development company, announced today it has signed a worldwide, exclusive license agreement with Genoscience, a French company focused on viral disease therapeutics, to develop and commercialize BL-8020, an orally available treatment for Hepatitis C.

24 Jan 2012

Younger breast cancer survivors face more serious mental issues

Quality of life in younger patients treated for breast cancer is seriously compromised and these women suffer from severe psychological distress, infertility, premature menopause, a decrease in physical activity and weight gain, according to a study by researchers at UCLA's Jonsson Comprehensive Cancer Center.

24 Jan 2012

Study shows childhood experiences have long-term effects on health in midlife

Nurturing mothers have garnered accolades for rescuing skinned knees on the playground and coaxing their children to sleep with lullabies. Now they're gaining merit for their offspring's physical health in middle age.

24 Jan 2012

A*STAR, GE Global Research join forces in integrated advanced medical imaging technologies

GE Global Research, the central technology development arm for GE Healthcare and all of GE's businesses, has signed a Memorandum of Understanding (MOU) with Singapore's Agency of Science, Technology and Research (A*STAR). This agreement will focus on advancing current medical imaging technologies and diagnostics to enable more accurate, earlier and faster clinical diagnoses of cancer and other diseases. The partnership between A*STAR and GE Global Research brings together two world-class research institutions, integrating their deep domain expertise in biomedical, science, and engineering capabilities to support this effort.

22 Jan 2012

New data from Infinity saridegib and gemcitabine Phase 1b/2 combination trial on pancreatic cancer

Infinity Pharmaceuticals, Inc. today announced updated data from the Phase 1b portion of an ongoing Phase 1b/2 clinical trial of saridegib in combination with the chemotherapy gemcitabine in patients with previously untreated, metastatic pancreatic cancer.

20 Jan 2012

Novel imaging platform reveals new details on aggressive cancer development

When cancers become aggressive and spread they are the most deadly. Unfortunately, little is known about how to stop this development. A new imaging platform developed by Lawson Health Research Institute's Drs. Ann Chambers and John Lewis is providing insight into just that - the exact moment when cancer cells turn deadly.

20 Jan 2012

Rexahn receives approval to initiate RX-3117 Phase I trial in solid tumors

Rexahn Pharmaceuticals, Inc., a clinical stage pharmaceutical company developing and commercializing oncology and CNS therapeutics, today announced that it has secured Hungarian Regulatory Authority and Ethics Committee approval for Rexahn's initial Clinical Trial Application.

19 Jan 2012

Scientists use gold-filled silicon wafers to target and burn breast cancer cells

By shining infrared light on specially designed, gold-filled silicon wafers, scientists at The Methodist Hospital Research Institute have successfully targeted and burned breast cancer cells. If the technology is shown to work in human clinical trials, it could provide patients a non-invasive alternative to surgical ablation, and could be used in conjunction with traditional cancer treatments, such as chemotherapy, to make those treatments more effective.

18 Jan 2012

Almac, MGB Biopharma partner to manufacture MGB-BP3 gram positive antibacterial compound

MGB Biopharma and Almac's Sciences Business Unit have entered into a collaboration where Almac will manufacture the production of their lead gram positive antibacterial compound MGB-BP3.

17 Jan 2012

Geisinger, InVivo to conduct injectable biocompatible hydrogel preclinical study for PNI

InVivo Therapeutics Holdings Corp., a developer of groundbreaking technologies for the treatment of spinal cord injuries (SCI), and Geisinger Health System today announced a research collaboration to conduct a preclinical study using InVivo's injectable biocompatible hydrogel for the treatment of chronic pain caused by peripheral nerve compression.

17 Jan 2012

MD Anderson Orlando receives donation to fight against pancreatic cancer

MD Anderson Cancer Center Orlando has received a generous donation to help in the fight against pancreatic cancer. A $75,000 grant, funded by the Shirley E. Noland Foundation, will support the Pancreatic Cancer Translational Research Project at MD Anderson - Orlando.

17 Jan 2012

Sangart commences MP4CO Phase 1b study in sickle cell disease

Sangart, Inc., a global biopharmaceutical company dedicated to developing life-saving medicines specifically designed to enhance the perfusion and oxygenation of ischemic (oxygen deprived) tissues through targeted oxygen and other gas delivery, today announced the initiation of a Phase 1b study designed to evaluate the safety of MP4CO treatment in patients with sickle cell disease.

12 Jan 2012

USPTO issues patent to Unigene's peptide-based therapeutics for obesity

Unigene Laboratories, Inc., a leader in the design, delivery, manufacture and development of peptide-based therapeutics, today announced that it had been granted U.S. Patent No. 8,076,291 from the United States Patent and Trademark Office.

11 Jan 2012

Oramed files provisional patent application with USPTO for combination diabetes therapy

Oramed Pharmaceuticals Inc., a developer of oral drug delivery systems, announced today that it has filed a provisional patent application with the United States Patent and Trademark Office for a combination therapy of its lead compound, ORMD-0801 in combination with its oral exenatide formulation, ORMD-0901. There is no such approved combination product available on the market today.

11 Jan 2012

SANUWAVE PACE technology reverses negative effects of ischemic, reperfusion injuries

SANUWAVE Health, Inc., today reported publication of peer-reviewed, preclinical data conducted at Cleveland Clinic that demonstrate the ability of the Company's Pulsed Acoustic Cellular Expression (PACE®) technology to substantially decrease the detrimental effects of microcirculatory injury for certain ischemic (lack of blood flow) and reperfusion (restoration of blood flow) injuries.

11 Jan 2012

Telormedix raises 7.5 million CHF

Telormedix, a clinical stage biopharmaceutical company focused on TLR7 agonists in the treatment of cancer and inflammatory diseases, today announced that it has raised 7.5 Million CHF from existing investors Aravis Venture and Proquest Investments.

10 Jan 2012

CNBG, Aeras reach final agreement to develop new TB vaccines

The global fight against the tuberculosis epidemic receives a boost today as Aeras and the China National Biotec Group (CNBG) announce that they have reached final agreement to jointly develop new tuberculosis (TB) vaccines.

10 Jan 2012

Preclinical News and Research

GUMC licenses worldwide rights of 'theranostic' to BioMetrx

Sofie to receive U.S. patent for novel PET probes

Aphios receives NIH's Phase II SBIR grant to develop APH-0703 for AD

Genoscience, BioLineRx to develop and commercialize BL-8020 for HCV

Younger breast cancer survivors face more serious mental issues

Study shows childhood experiences have long-term effects on health in midlife

A*STAR, GE Global Research join forces in integrated advanced medical imaging technologies

New data from Infinity saridegib and gemcitabine Phase 1b/2 combination trial on pancreatic cancer

Novel imaging platform reveals new details on aggressive cancer development

Rexahn receives approval to initiate RX-3117 Phase I trial in solid tumors

Scientists use gold-filled silicon wafers to target and burn breast cancer cells

Almac, MGB Biopharma partner to manufacture MGB-BP3 gram positive antibacterial compound

Geisinger, InVivo to conduct injectable biocompatible hydrogel preclinical study for PNI

MD Anderson Orlando receives donation to fight against pancreatic cancer

Sangart commences MP4CO Phase 1b study in sickle cell disease

USPTO issues patent to Unigene's peptide-based therapeutics for obesity

Oramed files provisional patent application with USPTO for combination diabetes therapy

SANUWAVE PACE technology reverses negative effects of ischemic, reperfusion injuries

Telormedix raises 7.5 million CHF

CNBG, Aeras reach final agreement to develop new TB vaccines

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