GenVec, Inc. (Nasdaq: GNVC) announced today that data were presented on GenVec's respiratory syncytial virus (RSV) vaccine program at the "Keystone Symposium on Viral Immunity and Host Gene Influence", which is taking place in Keystone, Colorado from March 21-26, 2012. The poster titled "Respiratory Syncytial Virus Neutralizing Antibodies Induced by Recombinant Adenovirus Vectors" #116 was presented on March 22, 2012 in Poster Session 1. The data were generated by the VRC and GenVec under a Cooperative Research and Development Agreement (CRADA). The presentation was given by Man Chen, PhD, Research Fellow, Viral Pathogenesis Laboratory, at the Vaccine Research Center (VRC) of the National Institutes of Health (NIH).
Data presented at the conference demonstrated encouraging preclinical proof-of-concept findings generated in non-human primates. Specifically, the data show GenVec's vaccine technology induced neutralizing antibody, and significant T-cell responses with a single administration. The immune responses were consistent with protective responses without disease potentiation and multiple administrations increased the neutralizing antibody responses.
"These data clearly demonstrate in a primate model that a vaccine utilizing our technology has significant potential to prevent RSV," stated Jason Gall, PhD, Senior Director of Research at GenVec and the company's lead RSV scientist. "These data support continued development of our pipeline of infectious disease vaccines based on our viral vector technology."