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Research explores the biophysical behavior of SARS-CoV-2 nucleocapsid protein

In a groundbreaking paper currently available on the bioRxiv* preprint server, the researchers from the Washington University School of Medicine and Stony Brook University showed how nucleocapsid protein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is dynamic, disordered and phase separates with RNA – informing, in turn, the discovery of drugs that disrupt viral packaging.

21 Jun 2020

Environmental conditions affect the stability of SARS-CoV-2, study finds

A new study led by Marshall University researcher M. Jeremiah Matson found that environmental conditions affect the stability of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human nasal mucus and sputum.

21 Jun 2020

Infants tested positive for COVID-19 mostly have mild illness with fever

A report from Ann & Robert H. Lurie Children's Hospital of Chicago shows that infants under 90 days of age who tested positive for COVID-19 tend to be well, with little or no respiratory involvement. Fever was often found to be the primary or only symptom.

21 Jun 2020

Study finds widespread support for public health measures to limit spread of COVID-19

No mass gatherings. Stay-at-home orders. Nonessential business closures. Use of cloth face coverings. In April, these and other measures were adopted by states to try to mitigate the spread of COVID-19 in the U.S. and across the globe.

21 Jun 2020

New book shows meditation can reduce conflict and divisions in society

The COVID-19 pandemic has put societies everywhere under extreme stress, and collective stress is often a precursor to outbreaks of violence. Striking features of this global health crisis have been the collective anxiety of the population, the wide variations in the way governments have responded, and the varying degree of their success.

21 Jun 2020

Young adults from disadvantaged neighborhoods show differences in the epigenome

The neighborhood a child grows up in may influence their health for years to come in previously invisible ways.

21 Jun 2020

Study takes new treatment approach for blood cancer

In an effort to improve the survival of patients with myeloproliferative neoplasms, a type of leukemia, researchers inhibited a specific protein (alpha5beta1 integrin) to decrease the number of large bone marrow cells (megakaryocytes) in an experimental model.

21 Jun 2020

Unexpected discovery helps explain fundamental mystery about how muscles work

Researchers at the Max Delbrück Center for Molecular Medicine in the Helmholtz Association developed a mouse model that enables them to look inside a working muscle and identify the proteins that allow the sarcomere to contract, relax, communicate its energy needs, and adapt to exercise.

21 Jun 2020

Systems approach needed to address challenges of globally interconnected food system

Global food production is incredibly efficient, and the world's farmers produce enough to feed the global population.

21 Jun 2020

Study shows changes in brain dynamics at rest following a relationship breakup

During a person's life, the experience of a stressful life event can lead to the development of depressive symptoms, even in a non-clinical population.

21 Jun 2020

Researchers discover new and improved way to treat poor-prognosis blood cancer

Researchers at Children's Cancer Institute have discovered what could prove a new and improved way to treat the poor-prognosis blood cancer, acute myeloid leukemia or AML.

21 Jun 2020

Brain-transportable soy derivate reduces memory degradation in mice

In a study that could help one day give a literal meaning to food for thought, researchers from Kyushu University in Japan have reported that a protein fragment that makes its way into the brain after being ingested can reduce memory degradation in mice treated to simulate Alzheimer's disease.

21 Jun 2020

The underlying cause of ethnic differences in COVID-19 remains unexplained

Higher rates of severe COVID-19 infections in Black, Asian and Minority Ethnic (BAME) populations are not explained by socioeconomic or behavioral factors, cardiovascular disease risk, or by vitamin D status, according to new research led by Queen Mary University of London.

21 Jun 2020

Killifish model helps unravel molecular events that lead to loss of protein homeostasis during brain aging

Aging is the main risk factor for dementia and Parkinson's disease. As age progresses, toxic protein aggregates pile up in the brain and impair neuronal function.

21 Jun 2020

Drama-based resources help Kingston University nursing students to cope with coronavirus pandemic

A set of drama-based resources to help Kingston University, London nursing students working during the Covid-19 pandemic have been put together through a collaboration with world-leading performing arts school Guildhall School of Music & Drama, London.

21 Jun 2020

Direct structural link between SARS-CoV-2 and essential fatty acid

Now, a new study published on the preprint server bioRxiv in June 2020 reports the discovery of a novel free fatty acid (FFA) binding pocket on the SARS-CoV-2 virus that could explain in part the viral effects of hyperinflammation, immune modulation, and membrane structure.

21 Jun 2020

Balanced B and T cell response required to control SARS-CoV-2

A new study by researchers in the Netherlands and published on the preprint server bioRxiv in June 2020 describes the differences in T and B cell responses seen in patients with severe COVID-19.

21 Jun 2020

Indonesians prefer to seek initial TB care at private clinics

A preference by Indonesians to seek initial care for tuberculosis at private clinics rather than public facilities is resulting in diagnostic delays and escalated costs, says a new study.

20 Jun 2020

Novel formulation could provide a better treatment for patients with prostate cancer

A novel formulation of the prostate cancer drug abiraterone acetate - currently marketed as Zytiga - will dramatically improve the quality of life for people suffering from prostate cancer, as pre-clinical trials by the University of South Australia show the new formulation improves the drug's effectiveness by 40 per cent.

20 Jun 2020

Near-infrared photoimmunotherapy could improve treatment for malignant lung cancer

Treating a rare type of malignant lung cancer could improve, thanks to near-infrared irradiation and a cancer-targeting compound. Nagoya University oncologist Kazuhide Sato and colleagues tested the treatment and published their findings in the journal Cells.

20 Jun 2020

Research News and Research

Research explores the biophysical behavior of SARS-CoV-2 nucleocapsid protein

Environmental conditions affect the stability of SARS-CoV-2, study finds

Infants tested positive for COVID-19 mostly have mild illness with fever

Study finds widespread support for public health measures to limit spread of COVID-19

New book shows meditation can reduce conflict and divisions in society

Young adults from disadvantaged neighborhoods show differences in the epigenome

Study takes new treatment approach for blood cancer

Unexpected discovery helps explain fundamental mystery about how muscles work

Systems approach needed to address challenges of globally interconnected food system

Study shows changes in brain dynamics at rest following a relationship breakup

Researchers discover new and improved way to treat poor-prognosis blood cancer

Brain-transportable soy derivate reduces memory degradation in mice

The underlying cause of ethnic differences in COVID-19 remains unexplained

Killifish model helps unravel molecular events that lead to loss of protein homeostasis during brain aging

Drama-based resources help Kingston University nursing students to cope with coronavirus pandemic

Direct structural link between SARS-CoV-2 and essential fatty acid

Balanced B and T cell response required to control SARS-CoV-2

Indonesians prefer to seek initial TB care at private clinics

Novel formulation could provide a better treatment for patients with prostate cancer

Near-infrared photoimmunotherapy could improve treatment for malignant lung cancer

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