Infectious Diseases News and Research

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New reference guide can help HIV care providers treat chronic pain

Recent studies suggest many individuals with HIV have chronic pain. Estimates range from 39 percent all the way to 85 percent. Chronic pain is an important comorbid condition in individuals with HIV, as it is common and causes substantial disability.

22 Mar 2016

TGen investigators help track hypervirulent strep outbreak in southwestern U.S.

The Translational Genomics Research Institute (TGen) has helped state, local and tribal health officials identify an outbreak of "hypervirulent" strep bacteria in the American Southwest.

22 Mar 2016

Sandia engineers aim to develop autonomous device to passively monitor mosquito-borne diseases

Mosquitoes are deadly efficient at spreading disease. Despite vaccines and efforts to eradicate the pesky insects, they continue to infect humans with feared diseases like Zika virus, malaria and West Nile virus.

22 Mar 2016

Subcutaneous injection of raltegravir can protect against vaginal HIV transmission

Vaginal transmission accounts for the majority of new HIV infections worldwide. Forms of pre-exposure prophylaxis (PrEP) such as vaginal gels and vaginal rings designed to prevent HIV transmission have encountered poor efficacy in human trials due to problems with adherence.

22 Mar 2016

Antibodies given within one day of SHIV exposure can clear the virus

Scientists at the Oregon National Primate Research Center today revealed that infant rhesus macaques treated with antibodies within 24 hours of being exposed to SHIV, a chimeric simian virus that bears the HIV envelope protein, were completely cleared of the virus.

22 Mar 2016

World TB Day 2016: WHO calls to Unite to End TB

In advance of World TB Day, to be observed on 24 March, the World Health Organization is calling on countries and partners to Unite to End TB.

22 Mar 2016

TGen scientists highlight advantages of using RNA-sequencing in precision medicine

Uncovering the genetic makeup of patients using DNA sequencing has in recent years provided physicians and their patients with a greater understanding of how best to diagnose and treat the diseases that plague humanity. This is the essence of precision medicine.

22 Mar 2016

Advanced genomic sequencing tracks deadly blood infection in cancer patients

The Translational Genomics Research Institute, working with international investigators, have discovered the source of a potential deadly blood infection in more than 50 South American cancer patients.

21 Mar 2016

N-KICS tool helps describe intensity of nursing care for children with CMC

Recent medical advances have resulted in increased survival of children with complex medical conditions (CMC), such as cerebral palsy, complex chromosomal anomalies, major congenital heart diseases and respiratory disease.

21 Mar 2016

Computer-assisted methods may help as decision support system to combat Zika virus

Global climate change, international travel, and ineffective vector control programs are aiding the emergence of infectious diseases globally. The currently expanding Zika virus (ZIKV) epidemic is one such problem.

21 Mar 2016

Simple TB screening and isoniazid can be effective for HIV patients at risk for TB

The number one killer of HIV patients in resource-limited areas, including parts of Africa and India, is tuberculosis (TB), underscoring the need for optimal treatments and effective strategies to address this deadly co-infection. But TB is harder to detect in HIV-infected patients and diagnostic test results take time, so many healthcare providers prescribe multi-drug TB treatments as a precaution.

20 Mar 2016

Findings could be final puzzle piece in developing effective dengue vaccine

In a small clinical trial led by the Johns Hopkins Bloomberg School of Public Health, researchers say that a promising single-dose dengue vaccine, developed by scientists at the National Institutes of Health, was 100 percent effective in preventing human volunteers from contracting the virus, the most prevalent mosquito-borne virus in the world.

18 Mar 2016

Clinical study finds no added benefit of using four TB drugs to save people with advanced HIV/AIDS

In a report on the so-called REMEMBER (Reducing Early Mortality and Early Morbidity by Empiric Tuberculosis Treatment) study -- a 10-nation, randomized clinical trial of adult outpatients -- investigators concluded that there was no added benefit of using four drugs for TB over just using one drug, isoniazid, to save lives in people with advanced HIV/AIDS.

18 Mar 2016

Study: Statin drugs can reduce time to clear tuberculosis infection in mice

In a study using mice, the Johns Hopkins University School of Medicine infectious disease experts have added to evidence that statin drugs — known primarily for their cholesterol-lowering effects — can significantly reduce the time it takes to clear tuberculosis infection.

17 Mar 2016

St. Jude scientists develop insights to guide development of powerful novel anti-influenza drugs

By analyzing the molecular details of how artificially created drug-resistant flu strains manage to survive treatment, St. Jude Children's Research Hospital scientists have developed insights to guide development of powerful new anti-influenza drugs. These compounds will target a viral enzyme critical to the virus' proliferation in the body.

15 Mar 2016

Biological change in mosquito mating could be used to fight mosquito-borne diseases

Genetic cues from male Aedes aegypti mosquitoes passed on during sex affect which genes are turned on or off in a females' reproductive tract post-mating, including genes related to blood feeding, egg development and immune defense, according to new Cornell research.

14 Mar 2016

NIH-funded investigators develop therapeutic compound effective against malaria

An international team that includes NIH-funded researchers at Stanford University has developed a therapeutic compound that is effective in inhibiting Plasmodium falciparum, one of five species of parasite that infects people with malaria, and the strain which causes the highest number of malaria deaths.

13 Mar 2016

Effective ways to ensure a long, healthy life

More people may be living to 100 and beyond than ever before, but the real challenge is how to become one of them yourself, and how to care for an aging population.

11 Mar 2016

Study shows gut microbes alter platelet function, heightens risk of heart attack and stroke

In a combination of both clinical studies of over 4,000 patients and animal model studies, Cleveland Clinic researchers have demonstrated -- for the first time -- that gut microbes alter platelet function and risk of blood clot-related illnesses like heart attack and stroke.

11 Mar 2016

Low bone mass higher in HIV-infected males than in females

Accumulating evidence suggests that rates of low bone mass are greater in HIV-infected males than in females. Researchers led by Grace Aldrovandi, MD, chief of the Division of Infectious Diseases at Children's Hospital Los Angeles, studied 11 biomarkers associated with inflammation, bone loss and/or bone formation in about 450 individuals - assessed by sex and HIV status - to try to determine causes of this differential bone loss.

11 Mar 2016

Infectious Diseases News and Research

New reference guide can help HIV care providers treat chronic pain

TGen investigators help track hypervirulent strep outbreak in southwestern U.S.

Sandia engineers aim to develop autonomous device to passively monitor mosquito-borne diseases

Subcutaneous injection of raltegravir can protect against vaginal HIV transmission

Antibodies given within one day of SHIV exposure can clear the virus

World TB Day 2016: WHO calls to Unite to End TB

TGen scientists highlight advantages of using RNA-sequencing in precision medicine

Advanced genomic sequencing tracks deadly blood infection in cancer patients

N-KICS tool helps describe intensity of nursing care for children with CMC

Computer-assisted methods may help as decision support system to combat Zika virus

Simple TB screening and isoniazid can be effective for HIV patients at risk for TB

Findings could be final puzzle piece in developing effective dengue vaccine

Clinical study finds no added benefit of using four TB drugs to save people with advanced HIV/AIDS

Study: Statin drugs can reduce time to clear tuberculosis infection in mice

St. Jude scientists develop insights to guide development of powerful novel anti-influenza drugs

Biological change in mosquito mating could be used to fight mosquito-borne diseases

NIH-funded investigators develop therapeutic compound effective against malaria

Effective ways to ensure a long, healthy life

Study shows gut microbes alter platelet function, heightens risk of heart attack and stroke

Low bone mass higher in HIV-infected males than in females

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