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CSIRO study on the effects of COVID-19 on weight and well being

The CSIRO, Australia's federal government agency responsible for scientific research, has come up with a study looking at the emotional well being and weight loss or gain associated with the COVID-19 pandemic and the forced stay-at-home measures.

16 Jun 2020

Antibiotic X-206 effective against SARS-CoV-2 in vitro

The current study published on the preprint server bioRxiv aims to understand how these compounds affect SARS-CoV-2 in vitro. The researchers from Aarhus University in Denmark examined 11 natural PEIs, with a single synthetic analog, screening them for inhibitory activity against the CPE of SARS-CoV-2 infecting cultured cells with overexpression of TMPRSS2, a serine protease that is instrumental in cleaving the spike protein of the virus.

16 Jun 2020

Hepatitis C virus co-opts an immune protein to evade antiviral defenses

By discovering a trick the hepatitis C virus uses to evade the immune system, scientists have identified a new antiviral defense system that could be used to treat many virus infections, according to new research published today in eLife.

16 Jun 2020

Study: One in five adults experienced a decrease in their sexual behavior early in the pandemic

One in five adults in the United States report they have experienced change - mostly a decrease - in their sexual behavior during the early months of the COVID-19 pandemic, according to a new study by Indiana University researchers.

16 Jun 2020

Anti-TNF drug preserves beta-cell function in newly diagnosed pediatric patients with Type 1 diabetes

In research led by a University at Buffalo pediatric endocrinologist, a drug called golimumab showed that it preserved beta-cell function in children and young adults with newly diagnosed Type 1 diabetes, according to findings from a Phase 2 study.

16 Jun 2020

TERAVOLT tracks outcomes of people with thoracic cancers affected by COVID-19

New data from TERAVOLT, a global consortium that tracks outcomes of people with thoracic cancers affected by COVID-19, offers clues as to why they experienced a high death rate of 33% when the coronavirus swept across Europe.

16 Jun 2020

Researchers create superior bone grafts using primitive stem cells

Although most broken bones can be mended with a firm cast and a generous measure of tender loving care, more complicated fractures require treatments like bone grafting.

16 Jun 2020

Two potent small molecules appear to suppress tumor growth in multiple cancers

City of Hope scientists have identified and developed two potent small molecules that appear to suppress tumor growth in multiple cancers even when other treatments cease to work, possibly due to the development of drug resistance.

16 Jun 2020

Cancer results from interaction between individual’s genetics and exposure to carcinogens

A new study led by the University of Hawai?i Cancer Center looks into how and why certain individuals develop cancer and others do not.

16 Jun 2020

Scientists discover unexpected role of heat shock proteins during neuronal differentiation

A research team led by Dr Chaogu Zheng from the School of Biological Sciences at the University of Hong Kong, in collaboration with a team led by Professor Martin Chalfie (2008 Nobel Laureate in Chemistry) from the Department of Biological Sciences at Columbia University, recently discovered an unexpected role of the heat shock proteins, also known as the molecular chaperones, during neuronal differentiation, which refers to the process a neuron takes to acquire its shape and function.

16 Jun 2020

Scientists evaluate SARS-CoV-2 infection risks in livestock, poultry, pets and wildlife

A large-scale single-cell screening endeavor on a wide variety of animals showed that cells targeted by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are most abundant in cats, but are also found in other animals – unveiling a valuable resource for controlling the ongoing disruptive coronavirus disease (COVID-19) pandemic.

16 Jun 2020

Experts evaluate options for treating cognitive deficits in multiple sclerosis

Experts in cognitive research evaluated the status of available treatments as well as promising strategies for treating cognitive deficits in multiple sclerosis.

16 Jun 2020

Researchers develop a simple tool for making mouse models of COVID-19

Until there are effective treatments or vaccines, the COVID-19 pandemic will remain a significant threat to public health and economies around the world. A major hurdle to developing and testing new anti-viral therapies and vaccines for COVID-19 is the lack of good, widely available animal models of the disease.

16 Jun 2020

Research team generates comprehensive developmental map of human T-cells

Chintan Parekh, MD, of The Saban Research Institute of Children's Hospital Los Angeles, has led a team of investigators that generated a comprehensive roadmap for how T-cells develop in the human thymus.

16 Jun 2020

Key factors to "flattening the curve": Western Washington state's COVID-19 experience

Despite having the first confirmed case of coronavirus and the first major COVID-19 outbreak in the United States, the state of Washington implemented a response plan that kept its death rate the lowest among all states that have had major outbreaks.

16 Jun 2020

Severity of COVID-19 linked to heparanase activity and heparan sulfate levels

Researchers at Radboud University Medical Center in the Netherlands reported an increase of heparanase activity and heparan sulfate levels in the plasma of patients with coronavirus disease (COVID-19), which was also associated with the severity of the condition – suggesting, in turn, potential treatment utility of low molecular weight heparins. The paper is currently available on the medRxiv* preprint server.

16 Jun 2020

Persistent DNA damage in the placenta can affect embryonic growth

Scientists at the Stowers Institute for Medical Research have shown that a dysfunctional placenta can play a previously unrecognized role during the earliest stages of development in mouse models of Cornelia de Lange syndrome.

16 Jun 2020

Exposure to certain e-cig cartridges may cause fatal lung damage

Researchers at the University of Rochester Medical Center, New York, have shown that long-term exposure to certain electronic nicotine delivery systems (ENDS) may cause lung toxicity and injury among vapers.

16 Jun 2020

Including patients in hospital discharge letters could enhance outcomes of care

Sending discharge letters to patients as well as their GPs when they leave UK hospitals could make a substantial difference to patient outcomes, according to a new study by University of Warwick researchers.

16 Jun 2020

How novel coronavirus affects children

New insights into the clinical and epidemiological characteristics of pediatric patients with coronavirus disease 2019 (COVID-19) could facilitate early identification and intervention in suspected patients, according to a study publishing on June 16, 2020 in the open-access journal PLOS Medicine by Xihui Zhou of the First Affiliated Hospital of Xi'an Jiaotong University, China and colleagues.

16 Jun 2020

Research News and Research

CSIRO study on the effects of COVID-19 on weight and well being

Antibiotic X-206 effective against SARS-CoV-2 in vitro

Hepatitis C virus co-opts an immune protein to evade antiviral defenses

Study: One in five adults experienced a decrease in their sexual behavior early in the pandemic

Anti-TNF drug preserves beta-cell function in newly diagnosed pediatric patients with Type 1 diabetes

TERAVOLT tracks outcomes of people with thoracic cancers affected by COVID-19

Researchers create superior bone grafts using primitive stem cells

Two potent small molecules appear to suppress tumor growth in multiple cancers

Cancer results from interaction between individual’s genetics and exposure to carcinogens

Scientists discover unexpected role of heat shock proteins during neuronal differentiation

Scientists evaluate SARS-CoV-2 infection risks in livestock, poultry, pets and wildlife

Experts evaluate options for treating cognitive deficits in multiple sclerosis

Researchers develop a simple tool for making mouse models of COVID-19

Research team generates comprehensive developmental map of human T-cells

Key factors to "flattening the curve": Western Washington state's COVID-19 experience

Severity of COVID-19 linked to heparanase activity and heparan sulfate levels

Persistent DNA damage in the placenta can affect embryonic growth

Exposure to certain e-cig cartridges may cause fatal lung damage

Including patients in hospital discharge letters could enhance outcomes of care

How novel coronavirus affects children

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