Clinical Trial News and Research

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Researchers identify genetic factor linked to development of diabetic peripheral neuropathy

Researchers from Joslin Diabetes Center, using a genome-wide association study, have identified a genetic factor linked to the development of diabetic peripheral neuropathy.

12 Jun 2019

Warfarin-treated patients benefit from increasing their vitamin K intake, finds study

When prescribed the anticoagulant drug warfarin, many patients are told to limit foods rich in vitamin K, such as green vegetables.

12 Jun 2019

Novel agent shown to have dual mechanism of action to eliminate cancer

Results from a study spearhead by researchers at the Vall d´Hebron Institute of Oncology (VHIO), show that the blockade of the multi-functional cytokine LIF induces tumor-infiltrating T Cells to hone in on and eliminate cancer.

11 Jun 2019

Researchers succeed in conquering chronic infection with hepatitis B virus

Researchers at Helmholtz Zentrum München and the Technical University of Munich, working in collaboration with researchers at the University Medical Center Hamburg-Eppendorf and the University Hospital Heidelberg, have for the first time succeeded in conquering a chronic infection with the hepatitis B virus in a mouse model.

11 Jun 2019

Using molecular biomarkers to guide the choice of therapies for metastatic pancreatic cancer

A new pilot study demonstrated the feasibility of using molecular tumor markers as the basis for selecting the chemotherapeutic agents to use in patients with metastatic pancreatic cancer.

11 Jun 2019

Tart cherry reduces joint pain and sore muscles in some breast cancer patients, study shows

Tart cherry reduces the musculoskeletal effects of aromatase inhibitors in patients with non-metastatic breast cancer, according to new findings from a clinical trial by researchers at Marshall University Joan C. Edwards School of Medicine and Edwards Comprehensive Cancer Center.

10 Jun 2019

Drug that targets the immune system can delay type 1 diabetes in high risk children, adults

A drug that targets the immune system can delay the onset of type 1 diabetes an average of two years in children and adults at high risk, according to findings from TrialNet's Teplizumab (anti-CD3) Prevention Study published in the New England Journal of Medicine.

10 Jun 2019

Myeloma UK launches new research program to support patient-centric myeloma clinical trials

Myeloma UK is launching a new research program to continue support for patient-centric myeloma clinical trials in the UK, the UK Myeloma Research Alliance-Myeloma UK-Concept and Access Research Programme.

10 Jun 2019

Diabetes drug reduces cardiovascular events and kidney problems, study finds

A clinical trial that followed more than 9,900 people in 24 countries has found that the drug dulaglutide reduced cardiovascular events and kidney problems in middle-aged and older people with Type 2 diabetes.

10 Jun 2019

Rapid fluid removal from patients with failing kidneys linked to increased risk of death

The faster fluid is removed using continuous dialysis from patients with failing kidneys, the higher the likelihood they will die in the next several months, according to a study published today in JAMA Network Open by University of Pittsburgh School of Medicine researchers.

8 Jun 2019

Robotic surgery for oropharyngeal cancer not better than radiation therapy, study finds

In 2012, scientists at Lawson Health Research Institute launched the world's first clinical trial comparing robotic surgery to radiation therapy for the treatment of oropharyngeal cancer (cancer at the back of the throat).

7 Jun 2019

Three-drug combination could be effective therapy for people with advanced melanoma

A UCLA-led research team has pinpointed a three-drug combination that could prove to be an effective new therapy for people with a specific type of advanced melanoma.

7 Jun 2019

New immunosuppressive regimens may improve outcomes for kidney transplant patients

Preliminary results from a $5.2 million clinical trial led by University of Cincinnati researchers show that the immunosuppressive drug belatacept can help safely and effectively treat kidney transplant patients without the negative long-term side effects of traditional immunosuppressive regimens, the study's leaders announced this week.

6 Jun 2019

Nanotechnology treatment reverses multiple sclerosis symptoms in mice

A nanotechnology treatment derived from bone marrow stem cells has reversed multiple sclerosis symptoms in mice and could eventually be used to help humans, according to a new study led by University of California, Irvine researchers.

6 Jun 2019

Alzheimer's therapy may be effective in treating individuals addicted to opioids

Clinical trial results reveal that a medication used to treat Alzheimer's disease may also be an effective therapy for individuals addicted to opioids. The findings are published in The American Journal on Addictions.

6 Jun 2019

Chronic inflammation removes motivation by reducing dopamine in the brain

Why do we feel listless when we are recovering from an illness? The answer is, apparently, that low-grade chronic inflammation interferes with the dopaminergic signaling system in the brain that motivates us to do things.

5 Jun 2019

Home-based exercise program reduces subsequent falls in high-risk seniors

An in-home exercise program reduced subsequent falls in high-risk seniors by 36 per cent, according the results of a 12-month clinical trial published today in the Journal of the American Medical Association.

4 Jun 2019

Researchers develop novel imaging test to predict immunotherapy response in kidney cancer

A novel imaging test shows promise for identifying kidney cancer patients most likely to benefit from immunotherapy.

4 Jun 2019

Study shows both IDH-mutant WHO-defined molecular subgroups could benefit from PCV chemoradiotherapy

A recent, updated predictive analysis of the three WHO-defined molecular subgroups based on isocitrate dehydrogenase 1/2 (IDH) mutation status and 1p/19q co-deletion status represented in the high-risk treatment arms of the NRG Oncology clinical trial NRG-RTOG 9802 indicates that both IDH-mutant sub-groups (IDHmut-noncodel and IDHmut-codel) could benefit from the addition of PCV chemotherapy to radiotherapy treatment.

3 Jun 2019

Targeted breast cancer therapy shows 'encouraging' results

Researchers have developed a targeted therapy that may significantly increase the survival of pre-menopausal women with advanced breast cancer

3 Jun 2019

Clinical Trial News and Research

Researchers identify genetic factor linked to development of diabetic peripheral neuropathy

Warfarin-treated patients benefit from increasing their vitamin K intake, finds study

Novel agent shown to have dual mechanism of action to eliminate cancer

Researchers succeed in conquering chronic infection with hepatitis B virus

Using molecular biomarkers to guide the choice of therapies for metastatic pancreatic cancer

Tart cherry reduces joint pain and sore muscles in some breast cancer patients, study shows

Drug that targets the immune system can delay type 1 diabetes in high risk children, adults

Myeloma UK launches new research program to support patient-centric myeloma clinical trials

Diabetes drug reduces cardiovascular events and kidney problems, study finds

Rapid fluid removal from patients with failing kidneys linked to increased risk of death

Robotic surgery for oropharyngeal cancer not better than radiation therapy, study finds

Three-drug combination could be effective therapy for people with advanced melanoma

New immunosuppressive regimens may improve outcomes for kidney transplant patients

Nanotechnology treatment reverses multiple sclerosis symptoms in mice

Alzheimer's therapy may be effective in treating individuals addicted to opioids

Chronic inflammation removes motivation by reducing dopamine in the brain

Home-based exercise program reduces subsequent falls in high-risk seniors

Researchers develop novel imaging test to predict immunotherapy response in kidney cancer

Study shows both IDH-mutant WHO-defined molecular subgroups could benefit from PCV chemoradiotherapy

Targeted breast cancer therapy shows 'encouraging' results

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