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Neurobiologists distinguish in unprecedented detail the patterns of brain activity

Using hairlike microelectrodes and computer analysis, neurobiologists at Duke University Medical Center have demonstrated that they can see the detailed instant-to-instant electrical "brainscape" of neural activity across a living brain.

8 Dec 2004

Transplanted bone marrow cells reduce liver fibrosis in mice

Transplanted bone marrow cells can reduce carbon tetrachloride-induced liver fibrosis in mice and significantly improve their survival rates, according to a new study

8 Dec 2004

A new study has found fatty liver disease in nearly one third of American adults in a large urban population sample

The prevalence of the disease varied significantly among ethnic groups. Hispanics had a higher prevalence than whites, while blacks had a lower prevalence than whites.

8 Dec 2004

Accumulated exposure to lead may be an important but unrecognized risk for developing cataracts in men

Lead continues to pose a significant public health problem in spite of substantial reductions in lead exposure in the United States in the recent past, according to background information in the article.

8 Dec 2004

Men and women who were overweight in young adulthood and middle age have significantly higher Medicare costs in older age

According to background information, obesity is associated with increased risk of high blood pressure, diabetes, and certain cancers, and has been identified as a major risk factor for coronary heart disease (CHD).

8 Dec 2004

Zarnestra, a farnesyl transferase inhibitor, can help treat high-risk myelodysplastic syndrome patients

An oral targeted therapy gentle enough to be used by patients in their 70s or 80s is showing benefit in treating high-risk myelodysplastic syndrome (MDS), a pre-leukemic disorder that can progress to acute myelogenous leukemia (AML), according to a study presented at the annual meeting of the American Society of Hematology (ASH).

7 Dec 2004

Revlimid clinical data in newly diagnosed multiple myeloma presented

Celgene Corporation announced today that data evaluating clinical results on Revlimid (lenalidomide) as a new therapeutic approach for patients with newly diagnosed multiple myeloma (MM) was presented at the American Society of Hematology 46th Annual Meeting in San Diego.

7 Dec 2004

Combination of thalidomide and dexamethasone may be a promising treatment for multiple myeloma

The combination of two pills -- thalidomide and dexamethasone -- may be an effective alternative to the intravenous chemotherapy commonly prescribed to patients with multiple myeloma, according to a large collaborative study conducted by the Eastern Cooperative Oncology Group and led by a Mayo Clinic investigator.

7 Dec 2004

Human parathyroid gland most likely evolved from the gills of fish

The human parathyroid gland, which regulates the level of calcium in the blood, probably evolved from the gills of fish, according to researchers from King's College London.

6 Dec 2004

New clues in understanding why group A streptococci (GAS) has a range of bacterial afflictions in humans

Researchers have unlocked new clues in understanding why group A streptococci (GAS) has a range of bacterial afflictions in humans. One of the keys to this species of bacteria is its production of streptokinase (SK), an enzyme that activates plasminogen, the blood clot-dissolving protein in humans.

6 Dec 2004

New insight into anticoagulation therapies

Anticoagulation therapies, or treatments that reduce the amount of clotting factors in the blood, are quite common and used for a variety of reasons.

6 Dec 2004

Novel mutagenesis screen used to identify genetic suppressors of thrombosis

Researchers using a novel sensitized ENU (N-ethyl-N-nitrosourea, a carcinogen-induced animal tumor model established to grow malignant and benign tumors) mutagenesis (induction of mutation) screen in laboratory mice have developed a promising approach to genetic screening that can increase the likelihood of identifying dominant suppressors of thrombosis.

6 Dec 2004

New advances in sickle cell disease

Excruciating pain episodes, recurrent pneumonias, strokes, severe infections, chronic hemolytic anemia, and secondary pulmonary hypertension are common complications of sickle cell disease, a life-threatening inherited defect in blood that causes normally disc-shaped red blood cells to take on a sickle shape.

6 Dec 2004

Prevalence of overweight increased in children aged two to four years from low-income families

The prevalence of overweight increased from 1989 to 2000 in children aged two to four years from low-income families, according to an article in the December issue of The Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.

6 Dec 2004

Nanogen issued new patent for active biological sample preparation

Nanogen announced today that it was issued U.S. Patent No. 6,824,740, "Apparatus for Active Biological Sample Preparation," by the U.S. Patent and Trademark Office.

6 Dec 2004

Smoking, a major problem in plastic surgery

Smoking is known to cause heart disease and cancer, but most patients do not know that smoking can harm the chances of having successful plastic surgery operations.

6 Dec 2004

First live imaging of specialized immune system cells reveals new clues about body’s security system

To keep the body safe, the immune system enlists more than one form of protection. A circulating task force of immune system cells monitors the body’s periphery, and sends information back to field command centers — the lymph nodes — located at pivotal traffic points.

6 Dec 2004

Children with sickle cell disease who are at risk for a stroke need ongoing blood transfusions to reduce their risk

“This important study shows the value of continuing periodic blood transfusions in preventing the serious and debilitating consequences of stroke,” says NHLBI Acting Director Barbara Alving. “At the same time, there are risks of chronic transfusions and the decision to continue with this treatment must be made on a case-by-case basis.”

6 Dec 2004

Zevalin highly effective in first-line treatment of low-grade follicular lymphoma

Results from a clinical trial presented at the American Society of Hematology 46th Annual Meeting and Exposition (ASH) demonstrated that Zevalin (ibritumomab tiuxetan), administered as a first-line therapy, induced a 100 percent response rate in a small population of patients with low-grate follicular lymphoma (FL).

6 Dec 2004

Study shows long-term benefits for chronic myeloid leukemia patients receiving therapy with imatinib

CHU in Poitiers, France, yesterday announced results of a study showing that newly diagnosed patients with a certain form of leukemia who are treated early with imatinib are more likely to achieve complete cytogenetic responses (the elimination of leukemic cells, a major goal of therapy) and have improved long-term outcomes.

6 Dec 2004

Blood News and Research

Neurobiologists distinguish in unprecedented detail the patterns of brain activity

Transplanted bone marrow cells reduce liver fibrosis in mice

A new study has found fatty liver disease in nearly one third of American adults in a large urban population sample

Accumulated exposure to lead may be an important but unrecognized risk for developing cataracts in men

Men and women who were overweight in young adulthood and middle age have significantly higher Medicare costs in older age

Zarnestra, a farnesyl transferase inhibitor, can help treat high-risk myelodysplastic syndrome patients

Revlimid clinical data in newly diagnosed multiple myeloma presented

Combination of thalidomide and dexamethasone may be a promising treatment for multiple myeloma

Human parathyroid gland most likely evolved from the gills of fish

New clues in understanding why group A streptococci (GAS) has a range of bacterial afflictions in humans

New insight into anticoagulation therapies

Novel mutagenesis screen used to identify genetic suppressors of thrombosis

New advances in sickle cell disease

Prevalence of overweight increased in children aged two to four years from low-income families

Nanogen issued new patent for active biological sample preparation

Smoking, a major problem in plastic surgery

First live imaging of specialized immune system cells reveals new clues about body’s security system

Children with sickle cell disease who are at risk for a stroke need ongoing blood transfusions to reduce their risk

Zevalin highly effective in first-line treatment of low-grade follicular lymphoma

Study shows long-term benefits for chronic myeloid leukemia patients receiving therapy with imatinib

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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