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New tool can provide non-invasive decision support for NSCLC treatment

Personalized treatment options for patients with lung cancer have come a long way in the past two decades.

16 Oct 2020

Nanoparticles release bursts of calcium to reverse multidrug resistance in tumor cells

Multidrug resistance (MDR) -- a process in which tumors become resistant to multiple medicines -- is the main cause of failure of cancer chemotherapy.

16 Oct 2020

Patients with soft-tissue cancer show rapid and complete response to novel combination of immunotherapy

A patient with end-stage and rapidly progressing soft-tissue cancer whose tumor did not respond to standard treatment, had a "rapid and complete response" to a novel combination of immunotherapy, according to new research published by a team of scientists from John Theurer Cancer Center at Hackensack University Medical Center and the Georgetown Lombardi Comprehensive Cancer Center, both of whom are part of the Georgetown Lombardi Comprehensive Cancer Center Consortium.

16 Oct 2020

Moffitt study uncovers how specific molecules promote cancer progression

The development of cancer is a highly complicated process, involving multiple genes and signaling pathways that become upregulated or downregulated throughout different stages of tumor growth and spread.

15 Oct 2020

Genomic analysis of neuroblastoma sheds light on childhood solid tumors

Researchers have used insight from a comprehensive genomic analysis of neuroblastoma to learn about the process driving one of the most common childhood solid tumors. The findings revealed possible approaches for developing precision medicines to improve patient outcomes. St. Jude Children's Research Hospital scientists led the study, which appears today in the journal Nature Communications.

15 Oct 2020

Researchers develop breakthrough blood test for brain tumors

Genetic mutations that promote the growth of the most common type of adult brain tumors can be accurately detected and monitored in blood samples using an enhanced form of liquid biopsy developed by researchers at Massachusetts General Hospital.

14 Oct 2020

3D structural model of BAF complex modifies DNA architecture, provides clues on cancer

Scientists have created an unprecedented 3-dimensional structural model of a key molecular "machine" known as the BAF complex, which modifies DNA architecture and is frequently mutated in cancer and some other diseases.

14 Oct 2020

Researchers are developing a new class of compounds against various cancers

Researchers at The Wistar Institute and collaborators from the University of Notre Dame are developing anticancer compounds targeting a pathway of the endoplasmic reticulum (ER) stress response implicated in the development of multiple myeloma (MM), chronic lymphocytic leukemia (CLL) and lymphoma.

14 Oct 2020

Cancer-killing T cells release chemicals to direct swarms towards tumors

When immune system T cells find and recognise a target, they release chemicals to attract more T cells which then swarm to help subdue the threat, shows a new study published today in eLife.

13 Oct 2020

Scientists combine a chemotherapeutic and photodynamic approach to fight cancer

In their quest to destroy cancer cells, researchers are turning to combinational therapies more and more. Scientists from Germany and China have now combined a chemotherapeutic and photodynamic approach.

13 Oct 2020

Cancer patients who smoke more likely to quit with frequent, sustained telephone counseling

Recently diagnosed cancer patients who smoke are significantly more likely to quit and remain tobacco-free if they receive frequent and sustained telephone counseling, according to a new study led by researchers at Massachusetts General Hospital.

13 Oct 2020

CAR NKT cells offer a promising approach to combat hard-to-treat solid tumors

Natural killer T (NKT) cells, a type of immune cells known for their potent anti-cancer properties in murine tumor models, have been developed into a novel form of immunotherapy to treat patients with cancer.

13 Oct 2020

Neoadjuvant trial of combination immunotherapy has favorable outcomes in bladder cancer patients

Neoadjuvant, or pre-surgical, combination treatment with the immune checkpoint inhibitors tremelimumab (anti-CTLA-4) and durvalumab (anti-PD-1) was well-tolerated and showed early signs of activity in certain patients with localized bladder cancer who do not have standard treatment options available, according to a Phase I clinical trial conducted by The University of Texas MD Anderson Cancer Center.

13 Oct 2020

Researchers identify new mechanism underlying the progression of FAP-associated Desmoid tumor

Volume 11, Issue 26 of Oncotarget reported that in this study the authors studied the differences in mi RNA expression between sporadic and FAP-associated Desmoid tumors using microarray confirmed by quantitative PCR.

12 Oct 2020

Study shows how mutations in VAV1 gene may promote T-cell tumors in experimental mice

Life is an exquisite orchestration of growth and change, with checks and balances that fine-tune complex entwined interactions, both intrinsic and external.

12 Oct 2020

Researchers examine the cooperative effects of genes in suppressing neuroendocrine tumors in mice

Volume 11, Issue 28 of Oncotarget features "Genetic analysis of the cooperative tumorigenic effects of targeted deletions of tumor suppressors Rb1, Trp53, Men1, and Pten in neuroendocrine tumors in mice" by Xu et, al. which reported that the authors examined whether the TSGs Rb1, Trp53, Pten, and Men1 have cooperative effects in suppressing neuroendocrine tumors in mice.

12 Oct 2020

Tumor News and Research

New tool can provide non-invasive decision support for NSCLC treatment

Nanoparticles release bursts of calcium to reverse multidrug resistance in tumor cells

Patients with soft-tissue cancer show rapid and complete response to novel combination of immunotherapy

Moffitt study uncovers how specific molecules promote cancer progression

Genomic analysis of neuroblastoma sheds light on childhood solid tumors

Researchers develop breakthrough blood test for brain tumors

3D structural model of BAF complex modifies DNA architecture, provides clues on cancer

Researchers are developing a new class of compounds against various cancers

Cancer-killing T cells release chemicals to direct swarms towards tumors

Scientists combine a chemotherapeutic and photodynamic approach to fight cancer

Cancer patients who smoke more likely to quit with frequent, sustained telephone counseling

CAR NKT cells offer a promising approach to combat hard-to-treat solid tumors

Neoadjuvant trial of combination immunotherapy has favorable outcomes in bladder cancer patients

Researchers identify new mechanism underlying the progression of FAP-associated Desmoid tumor

Study shows how mutations in VAV1 gene may promote T-cell tumors in experimental mice

Researchers examine the cooperative effects of genes in suppressing neuroendocrine tumors in mice

A new therapeutic approach for Epstein-Barr virus-associated tumors

New study may lead to more effective, personalized cancer immunotherapies

New initiative identifies key parameters underlying effective anti-tumor immunity

Chemists suggest a new domino reaction to produce organic compounds against cancers

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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