Efficacy News and Research

RSS

Accelerating the design of minibinder therapeutics resilient to SARS-CoV-2 mutations

Multivalent protein-based minibinders hold great promise as potential prophylactic and treatment agents, as they can retain their activity against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern. This was revealed in a recent tour-de-force research study currently available on the bioRxiv* preprint server while the article undergoes the peer review process.

11 Jul 2021

Pfizer-BioNTech’s COVID-19 vaccine effective and safe for use among cancer patients

Researchers in Israel have conducted a study showing that the use of Pfizer-BioNTech’s coronavirus disease 2019 (COVID-19) vaccine appears to be safe and effective among patients with cancer.

11 Jul 2021

SARS-CoV-2 immunity due to prior infection or vaccination is similar, study says

A new study finds that the rate of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reinfection is low following one episode of the infection.

11 Jul 2021

Study examines SARS-CoV-2's inactivation across a range of UVC wavelengths

A recent study published on the preprint server medRxiv* describes the disinfection of SARS-CoV-2 using UVC irradiation at different wavelengths.

11 Jul 2021

Scientists analyze the sensitivity of SARS-CoV-2 Delta variant to monoclonal antibodies

The Delta variant was detected for the first time in India in October 2020 and has since spread throughout the world.

9 Jul 2021

Metabolites of intestinal bacteria can positively influence the efficacy of tumor therapies

Certain metabolites of bacteria from the intestine make immune cells more aggressive as a new study conducted by scientists from Würzburg and Marburg reveals. The findings could help improve cancer therapies.

9 Jul 2021

Stimulating immune cells to form special structures can potentiate pancreatic cancer chemotherapy

A new study from Queen Mary University of London has demonstrated that immune cells can be stimulated to assemble into special structures within pancreatic cancer such that, at least in a pre-clinical model, researchers can demonstrate an improvement in the efficacy of chemotherapy.

9 Jul 2021

Societies experience a sense of fatigue due to the pandemic

How a pandemic progresses in a country is largely determined by social, political and psychological processes. Predicting these socio-dynamics seems hardly possible until today; thus making it impossible to foresee the course the pandemic takes.

9 Jul 2021

Consumer checklist to support people locate effective treatment for eating disorders

In spite of many clinical options, people with mental health problems including eating disorders often do not access professional help within the crucial first 12 months - in part because of lack of information in the community about accessing targeted services.

9 Jul 2021

Can saliva metabolomics predict COVID-19 severity?

New research suggests that saliva metabolomics may be able to help prognosticate disease severity in COVID-19 positive individuals.

9 Jul 2021

New York City SARS-CoV-2 breakthrough cases predominantly Alpha and Iota variants

While Delta (B.1.617.2) has overtaken Alpha (B.1.1.7) as the dominant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant in the United States, Alpha remained a force to be reckoned with in New York City earlier this year. New research published on the preprint medRxiv* server details breakthrough infections in vaccinated and unvaccinated individuals living in New York City.

9 Jul 2021

Durable antibody response at least 8 months following vaccination with J&J COVID vaccine

A recent study by a team of scientists at Beth Israel Deaconess Medical Center and Janssen Vaccines & Prevention has demonstrated that humoral and cellular immunity elicited by the coronavirus disease 2019 (COVID-19) vaccine Ad26.COV2.S remains active for at least eight months.

9 Jul 2021

Study examines the effectiveness of fluorescent labels used to monitor liposome accumulation in tumors

Dmitri Simberg, PhD, an associate professor in the Department of Pharmaceutical Sciences in the Skaggs School of Pharmacy and a CU Cancer Center member, has released the results of a new study of the effectiveness of different types of fluorescent labels used to monitor the accumulation of liposomes in tumors.

8 Jul 2021

Early B cell signatures predict antibody responses to mRNA-based COVID-19 vaccine

Researchers in the United States have identified both antigen-specific and antigen non-specific predictive signatures of antibody responses to Moderna’s two-dose coronavirus disease 2019 (COVID-19) vaccine that protects against infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

8 Jul 2021

Intranasal COVID-19 vaccine protects animals against lethal COVID-19 infection

In a new study assessing the potential of a single-dose, intranasal COVID-19 vaccine, a team from the University of Iowa and the University of Georgia found that the vaccine fully protects mice against lethal COVID-19 infection.

8 Jul 2021

New genomics workbook helps people use their family history to assess disease risks

Researchers at the National Human Genome Research Institute, part of the National Institutes of Health, have developed the Families Sharing Health Assessment and Risk Evaluation (SHARE) workbook, which helps people use their family history to assess their risk for heart disease, diabetes, breast cancer and colorectal cancer.

8 Jul 2021

Innovative patient-centered approach to bolster dementia carer support

Support for carers of people living with dementia will be bolstered under a new and innovative patient-centered approach led by Flinders Caring Futures Institute researchers.

8 Jul 2021

New analysis finds muscle relaxant drugs to be largely ineffective for low back pain

Muscle relaxant drugs are largely ineffective for low back pain, despite being widely prescribed for this condition, suggests an analysis of the latest evidence published by The BMJ today.

8 Jul 2021

Compulsory covid-19 vaccination for care home workers is unnecessary, disproportionate and misguided, experts argue

In The BMJ today, experts argue that mandatory vaccination is “unnecessary, disproportionate, and misguided.”

8 Jul 2021

Striking increase in SARS-CoV-2 antibodies seen with prime dose AstraZeneca vaccine followed by Pfizer-BioNTech

Researchers in Germany have provided evidence that a booster shot of a messenger RNA (mRNA)-based coronavirus disease 2019 (COVID-19) vaccine following prime immunization with AstraZeneca’s adenoviral vector-based vaccine is sufficient to achieve high levels of neutralizing antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

8 Jul 2021

Efficacy News and Research

Accelerating the design of minibinder therapeutics resilient to SARS-CoV-2 mutations

Pfizer-BioNTech’s COVID-19 vaccine effective and safe for use among cancer patients

SARS-CoV-2 immunity due to prior infection or vaccination is similar, study says

Study examines SARS-CoV-2's inactivation across a range of UVC wavelengths

Scientists analyze the sensitivity of SARS-CoV-2 Delta variant to monoclonal antibodies

Metabolites of intestinal bacteria can positively influence the efficacy of tumor therapies

Stimulating immune cells to form special structures can potentiate pancreatic cancer chemotherapy

Societies experience a sense of fatigue due to the pandemic

Consumer checklist to support people locate effective treatment for eating disorders

Can saliva metabolomics predict COVID-19 severity?

New York City SARS-CoV-2 breakthrough cases predominantly Alpha and Iota variants

Durable antibody response at least 8 months following vaccination with J&J COVID vaccine

Study examines the effectiveness of fluorescent labels used to monitor liposome accumulation in tumors

Early B cell signatures predict antibody responses to mRNA-based COVID-19 vaccine

Intranasal COVID-19 vaccine protects animals against lethal COVID-19 infection

New genomics workbook helps people use their family history to assess disease risks

Innovative patient-centered approach to bolster dementia carer support

New analysis finds muscle relaxant drugs to be largely ineffective for low back pain

Compulsory covid-19 vaccination for care home workers is unnecessary, disproportionate and misguided, experts argue

Striking increase in SARS-CoV-2 antibodies seen with prime dose AstraZeneca vaccine followed by Pfizer-BioNTech

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News