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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Researchers confirm two new prognostic markers for triple negative breast cancer

Physicians who treat patients with triple negative breast cancer have two new ways to predict which patients may benefit most from the well-established post-surgery treatment known as AC chemotherapy, short for adjuvant doxorubicin and cyclophosphamide.

5 Dec 2019

New discovery on chromosomal function may shed light on human health and disease

Researchers have discovered key mechanisms and structural details of a fundamental biological process - how a cell nucleus and its chromosomal material reorganizes itself after cell division

5 Dec 2019

Using genomics to identify promising novel treatment for lymphatic filariasis

Using innovative RNA sequencing techniques, researchers at the University of Maryland School of Medicine Institute for Genome Sciences identified a promising novel treatment for lymphatic filariasis, a disabling parasitic disease that is difficult to treat.

3 Dec 2019

Key component of immune response is activated by short RNAs, shows study

Ludwig-Maximilians-Universitaet (LMU) in Munich researchers report that a central component of the innate immune response is activated by two short RNAs which are produced by site-specific cleavage of a precursor RNA molecule - and both derivatives are generated by the same enzyme.

3 Dec 2019

Unexpected versatility of an ancient DNA repair factor revealed

If a bone breaks or a tendon snaps, you know to seek treatment immediately. But your most fragile and precious cellular commodity, chromosomal DNA, breaks with astounding frequency- some estimate as many as 10,000 times a day per cell- usually without consequence.

2 Dec 2019

Scientists discover new principle for activation of cancer genes

Researchers have long known that some genes can cause cancer when overactive, but exactly what happens inside the cell nucleus when the cancer grows has so far remained enigmatic.

2 Dec 2019

Scientists uncover functions of mysterious organelles in stress response

Stress is a normal response to physical and emotional stimuli, particularly when people face changes in their lives. Though it’s a normal feeling, long-term stress may lead to a range of health conditions. Though people feel stressed from time to time, not all stress is bad.

1 Dec 2019

ICR scientists carry out first comprehensive assessment of chemical probe resources

A new report urges biomedical researchers to use online web resources very carefully, taking into account their complementary benefits and weaknesses, when selecting small-molecule chemical probes to help answer their research questions.

28 Nov 2019

Home urine testing kit for prostate cancer could come soon

A new study from the University of East Anglia and the Norfolk and Norwich University Hospital may lead to people being able to test for prostate cancer from home, using urine samples. The study, which was published in the journal BioTechniques, describes a simple home urine collection test which can detect aggressive prostate cancer, and providing information on whether it requires to be treated, up to 5 years earlier than the comparable diagnostic methods of today.

28 Nov 2019

Study finds autism-related genetic mutations in aging brains of Alzheimer's patients

Researchers believe that autism is caused by mutations that occur sporadically in the egg or sperm or during pregnancy.

26 Nov 2019

Research could help design better flu vaccines

Each year millions of Americans become sick with the flu, hundreds of thousands are hospitalized and tens of thousands die. Getting the flu shot can reduce the chances of infection. But, at best, the vaccine is only effective 40% to 60% of the time, according to the CDC.

26 Nov 2019

Study reveals novel pathway to target colorectal cancer

While the emergence of precision medicine and immunotherapy has greatly improved outcomes for patients with colorectal cancer, new approaches are still needed for patients with late-stage disease who do not respond to these therapies.

26 Nov 2019

New electrochemical CRISPR biosensor can help improve diagnosis of diseases

The CRISPR/Cas technology can do more than alter genes. A research team at the University of Freiburg is using what are known as gene scissors - which scientists can use to edit genetic material - in order to better diagnose diseases such as cancer.

25 Nov 2019

Scientists record assembly of ribosomes in real time

A team of scientists from Scripps Research and Stanford University has recorded in real time a key step in the assembly of ribosomes--the complex and evolutionarily ancient "molecular machines" that make proteins in cells and are essential for all life forms.

22 Nov 2019

Accelerating Medicines Partnership program for Parkinson’s disease launches new data portal

The Accelerating Medicines Partnership program for Parkinson's disease (PD) has launched a data portal to provide de-identified information collected from 4,298 PD patients and healthy controls to researchers working to develop effective therapies for the disease.

22 Nov 2019

Charcot-Marie-Tooth disease study unearths a new mechanism of neurodegeneration

Charcot-Marie-Tooth disease is an inherited neurodegenerative condition that affects 1 in 2500 individuals.

21 Nov 2019

Scientists discover new molecular drivers of Parkinson's disease

Scientists at the Icahn School of Medicine at Mount Sinai have uncovered new molecular drivers of Parkinson's disease using a sophisticated statistical technique called multiscale gene network analysis.

20 Nov 2019

Teenage binge drinking may lead to anxiety and alcohol abuse in later life

Exposure to high levels of alcohol in adolescence may shape adult behaviors, predisposing them to a higher risk of anxiety and alcohol abuse later in life, a new study found.

19 Nov 2019

MIT researchers develop method to isolate T cells primed for certain allergies or infections

When your immune system is exposed to a vaccine, an allergen, or an infectious microbe, subsets of T cells that can recognize a foreign intruder leap into action.

19 Nov 2019

Research findings can be used in antiviral development against enterovirus infections

Despite their prevalence, there are no antivirals on the market against enteroviruses, and vaccines have been developed only against couple of serotypes. The production of vaccines against all enterovirus serotypes is not feasible, and so antiviral drugs may be the solution for most of the enterovirus infections.

19 Nov 2019