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Potential new drug for the treatment of sickle cell disease

The results were published in the June 2004 issue of The British Journal of Haematology (BJH). MX-1520 is a prodrug of vanillin, a very popular food additive generally regarded as safe (GRAS) by the FDA.

13 Sep 2004

Researchers have discovered a possible way to distinguish lethal from localized prostate cancers

If future studies show their test -- measuring the level of activity of a signaling pathway called Hedgehog -- can predict which prostate cancers will spread, the results could revolutionize decision making processes for prostate cancer patients, the researchers say.

13 Sep 2004

Inhaled nitrite spray may help babies diagnosed with persistent pulmonary hypertension of the newborn

Scientists from the National Institutes of Health (NIH) Clinical Center and the Loma Linda University School of Medicine have found that use of an inhaled nitrite spray may help babies diagnosed with persistent pulmonary hypertension of the newborn (PPHN).

13 Sep 2004

CA125 blood test may be superior to standard imaging techniques like CT scans

A new study shows that the CA125 blood test, which measures the level of protein produced by ovarian cancer cells in the blood, may be superior to standard imaging techniques like CT scans in predicting survival in patients with recurrent ovarian cancer.

13 Sep 2004

Chronic illnesses among children not adequately addressed

Current methods of delivering health care to kids are woefully unable to cope with a pediatric disease pendulum that has swung from acute to chronic illnesses, says a researcher at the Stanford University School of Medicine and Lucile Packard Children's Hospital.

13 Sep 2004

Chiron announces settlement with Roche in HIV patent dispute

Chiron Corporation has announced that it has reached a settlement with F. Hoffmann-La Roche (Roche) in a dispute over licensing fees and royalties that Chiron had asserted was owed to the company under a licensing agreement related to its U.S. Patent No. 6,531,276 (the "276 Patent").

12 Sep 2004

Higher blood levels of homocysteine may be associated with changes in deep brain tissue in middle-aged men

According to the article, high HCY levels have been associated with an increased risk for vascular diseases, and some studies have suggested that HCY may also increase the risk for brain atrophy and Alzheimer disease. Other studies have shown an inverse relationship between elevated HCY levels and cognitive functioning, the article states.

12 Sep 2004

Treatment with vitamin A and an omega-3 fatty acid slows down the progression of retinitis pigmentosa

Patients with retinitis pigmentosa, a progressive eye disease that can cause vision loss, who were treated with vitamin A and docosahexaenoic acid (DHA), a kind of omega-3 fatty acid, did not experience slowing of the progression of their disease

12 Sep 2004

Patients who experience medical or neurological complications following stroke are at a greater risk of dying in the hospital

Patients who experience medical or neurological complications following stroke, such as pneumonia or brain swelling, are at a greater risk of dying in the hospital, according to an article in the September 13 issue of The Archives Internal Medicine, one of the JAMA/Archives journals.

12 Sep 2004

New genetic test can predict cleft lip or palate

Researchers have developed a new genetic test that can help predict whether parents who have one child with the "isolated" form of cleft lip or palate are likely to have a second child with the same birth defect. Isolated clefts account for 70 percent of all cleft lip and palate cases.

10 Sep 2004

Spouses' emotions can effect psychological recovery after a heart attack or angioplasty

Psychological recovery after a heart attack or angioplasty may be delayed if patients’ spouses feel even more anxious or depressed than their ill partners, researchers say.

10 Sep 2004

PSA test is now all but useless for predicting prostate cancer risk

The PSA test, commonly used as a screening tool for detecting prostate cancer, is now all but useless for predicting prostate cancer risk, according to Stanford University School of Medicine researchers.

10 Sep 2004

Spinal cord injury specialist says 60 percent of his patients are obese

As Americans face a growing epidemic of obesity, people with spinal cord injuries find themselves particularly vulnerable to the serious complications that come with carrying around extra pounds.

10 Sep 2004

Cancer drug may reduce kidney disease in lupus

A drug that is already being tested as an anticancer agent, especially in lymphoma, may also reduce the kidney disease that is a result of systemic lupus, according to a researcher at Wake Forest University Baptist Medical Center.

10 Sep 2004

Grant to study genetics and drug interaction

A University of Minnesota researcher received a nearly $1 million grant from the National Institutes of Health (NIH) to study how genetic differences affect whether people will experience dangerous drug interactions and how to adjust medications to avoid those interactions.

10 Sep 2004

Computer scientists developing nurturing computers

Imagine a day when your computer will be able to let you know if you need a break, alert you to take medication or even go to the doctor.

10 Sep 2004

Discovery of way to regulate brain blood could lead to new treatments for stroke, migraine, Alzheimer’s

There may be new treatments for stroke, migraine, Alzheimer’s and other brain disorders, thanks to the discovery of a mechanism for regulating brain blood flow made by researchers at the University of British Columbia.

10 Sep 2004

Herbals, surgery and anesthesia don't always mix

The woman who swears by gingko biloba wonders why her mouth won't stop bleeding after wisdom tooth surgery. What she doesn't know is that the herbal remedy she takes religiously to enhance mental alertness also acts as a powerful blood thinner that inhibits clotting.

10 Sep 2004

Transthyretin discovery may halt progression of Alzheimer's

In a finding that may cause a dramatic shift in the way scientists and researchers search for a therapy for Alzheimer's disease, a team of researchers led by Jeff Johnson, an associate professor at the School of Pharmacy, has discovered that increased expression of a protein called transthyretin in the brain appears to halt the progression of the disease.

10 Sep 2004

Interim report on blood dioxin study made public

Interim results of state-of-the-art tests carried out for some long term residents in the New Plymouth suburb of Paritutu, New Zealnd, have shown a higher than normal level of dioxin in their blood.

10 Sep 2004