Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

Researchers pinpoint multiple zoonotic origins of SARS-CoV-2

In a pair of related studies, published July 26, 2022 online via First Release in Science, researchers at University of California San Diego, with colleagues on four continents, show that the origin of the COVID-19 pandemic in 2019 was at the Huanan Seafood Wholesale Market in Wuhan, China, and resulted from at least two instances of the SARS-CoV-2 virus jumping from live animal hosts to humans working or shopping there.

26 Jul 2022

Study identifies risks in the use of CRISPR therapeutics

The researchers caution: "The CRISPR genome editing method is very effective, but not always safe. Sometimes cleaved chromosomes do not recover and genomic stability is compromised - which in the long run might promote cancer."

25 Jul 2022

New way to test vaccines may be as rigorous and stringent as exposure to field strains of malaria

Malaria is the deadliest mosquito-borne parasitic infection of humans. In 2021, after a century of research, the World Health Organization (WHO) approved the world's first malaria vaccine.

20 Jul 2022

Identifying a core human microbiome

Researchers provide a critical review of the concept of the core human microbiome.

19 Jul 2022

Grant funds research that investigates relationships between certain fungi and specific cancers

Dr. Iliyan D. Iliev, an associate professor of immunology and microbiology in the Division of Gastroenterology and Hepatology and a member of the Jill Roberts Institute for Research in Inflammatory Bowel Disease at Weill Cornell Medicine, has been awarded a five-year, $1.25 million CRI Lloyd J. Old STAR (Scientists Taking Risks) Program grant from Cancer Research Institute (CRI).

19 Jul 2022

Study offers new insights into brain metastases in patients with melanoma

Brain metastasis is one of the most common causes of cancer-related deaths and occurs very frequently in patients with advanced melanoma.

18 Jul 2022

Frequent, regular rapid antigen testing plus isolation could cut COVID-19 risk among groups of people

Among oil-rig workers, shipping crews, and other groups of people who work closely together, COVID-19 can spread like wildfire. Yet trying to prevent spread with long quarantines can be just as disruptive.

15 Jul 2022

New high-throughput genomic array offers an in-depth view of the mouse epigenome

A new high-throughput genomic array offers an unprecedented look into the mouse epigenome, giving researchers an in-depth view into the basis of health and disease in a vital model organism.

13 Jul 2022

Mount Sinai receives $4.2 million to establish a Proteogenomic Data Analysis Center

The Office of Cancer Clinical Proteomics Research at the National Cancer Institute has awarded $4.2 million over five years to Mount Sinai researchers establishing a Proteogenomic Data Analysis Center to advance cancer research and treatments.

13 Jul 2022

GenomeBits representation of SARS-CoV-2 Delta and Omicron genome sequences

In a new study, researchers uncovered distinct genomic features of SARS-CoV-2 Delta and Omicron variants.

13 Jul 2022

How may the genetic differences observed in the current monkeypox virus outbreak impact immune responses induced by VACV vaccines?

Researchers assessed the impact of the vaccinia virus vaccine on the immune response against the monkeypox virus.

12 Jul 2022

Scientists explore mutations in the SARS-CoV-2 receptor-binding domain

Researchers assessed the different mutations of concern in the SARS-CoV-2 receptor-binding domain.

6 Jul 2022

Genetically engineered kidney organoids solve mystery of a rare disease

Researchers have solved a medical mystery in a poorly understood disease by uncovering which cells cause tumors in patients with tuberous sclerosis complex (TSC).

6 Jul 2022

New atomic-level models of spike protein play a key role in COVID-19 infection and immunity

When the coronavirus causing COVID-19 infects human cells, the cell's protein-processing machinery makes modifications to the spike protein that render it more flexible and mobile, which could increase its ability to infect other cells and to evade antibodies, a new study from the University of Illinois Urbana-Champaign found.

6 Jul 2022

Scientists uncover HIV’s sweet spot

HIV researchers have long been trying to identify the specific cells that the virus prefers to infect and hide in. They know that HIV favors a special type of immune cells called memory CD4 T cells.

5 Jul 2022

Researchers discover new family of sensing genes in enteric bacteria using AI

Using artificial intelligence, UT Southwestern researchers have discovered a new family of sensing genes in enteric bacteria that are linked by structure and probably function, but not genetic sequence.

30 Jun 2022

Review sheds light on the emergence and detection of antibiotic resistance in bioaerosols

Bioaerosols, or airborne biological particles containing viruses, fungal spores, bacteria, and pollen, play a key role in public health. Antibiotic resistance (AR), caused by antibiotic resistance genes (ARGs), could potentially cause global public health crises owing to horizontal gene transfer between same or similar bacterial bioaerosols.

30 Jun 2022

Bioinformatics News and Research

Further Reading

Researchers pinpoint multiple zoonotic origins of SARS-CoV-2

Study identifies risks in the use of CRISPR therapeutics

New way to test vaccines may be as rigorous and stringent as exposure to field strains of malaria

Identifying a core human microbiome

Grant funds research that investigates relationships between certain fungi and specific cancers

Study offers new insights into brain metastases in patients with melanoma

Frequent, regular rapid antigen testing plus isolation could cut COVID-19 risk among groups of people

New high-throughput genomic array offers an in-depth view of the mouse epigenome

Mount Sinai receives $4.2 million to establish a Proteogenomic Data Analysis Center

GenomeBits representation of SARS-CoV-2 Delta and Omicron genome sequences

How may the genetic differences observed in the current monkeypox virus outbreak impact immune responses induced by VACV vaccines?

Scientists explore mutations in the SARS-CoV-2 receptor-binding domain

Genetically engineered kidney organoids solve mystery of a rare disease

New atomic-level models of spike protein play a key role in COVID-19 infection and immunity

Scientists uncover HIV’s sweet spot

Researchers discover new family of sensing genes in enteric bacteria using AI

Review sheds light on the emergence and detection of antibiotic resistance in bioaerosols

Online version of algorithm shows how biases in RNA sequences affect gene expression

Study identifies critical genes and biological pathways related to COVID-19 myocarditis

Evolution of SARS-CoV-2 genomes based on continuing positive selection

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